[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627176":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":18,"responsibleParty":31,"collaborators":7,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":7,"eligibilityCriteria":41,"healthyVolunteers":37,"sex":42,"minAge":43,"maxAge":7,"enrollmentInfo":44,"targetDuration":7,"studyType":47,"phases":7,"briefSummary":48,"conditions":49,"keywords":7,"overallStatus":51,"whyStopped":7,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":61},{"fullName":5,"class":6},"Istinye University","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Laparoscopic Bariatric Surgery","Standard-of-care laparoscopic bariatric surgery (laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass) performed according to institutional protocols. No experimental intervention is introduced. The study prospectively observes perioperative serum bicarbonate changes and their association with pneumoperitoneum duration and early discharge readiness.",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"ilke dolgun","CONTACT","+905555485632","ilkeser2004@gmail.com",[19],{"facility":20,"status":7,"city":21,"state":22,"zip":23,"country":24,"countryCode":7,"cosmosGeoPoint":25,"geoPoint":30,"contacts":7},"Istinye Üniversity","Istanbul","Merkez Mahallesi","34250","Turkey (Türkiye)",{"type":26,"coordinates":27},"Point",[28,29],28.94966,41.01384,{"lat":29,"lon":28},{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","İlke Dolgun","Assoc. prof","100627176","serum-bicarbonate-changes-during-laparoscopic-bariatric-surgery-100627176",false,"NCT07445230","Serum Bicarbonate Changes During Laparoscopic Bariatric Surgery","Metabolic Effects of Pneumoperitoneum During Laparoscopic Bariatric Surgery: Association Between Perioperative Serum Bicarbonate Change and Early Discharge Readiness","Inclusion Criteria:\n\n* Adults aged ≥18 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic bariatric surgery (laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass)\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* ASA physical status IV or higher\n* Chronic obstructive pulmonary disease (COPD), asthma, or other severe chronic respiratory disease\n* Known chronic metabolic acidosis or renal failure\n* Major intraoperative complications (e.g., severe bleeding, conversion to open surgery)\n* Postoperative reoperation, intensive care requirement, or complications preventing standard recovery evaluation","ALL","18 Years",{"count":45,"type":46},85,"ESTIMATED","OBSERVATIONAL","Pneumoperitoneum during laparoscopic bariatric surgery induces carbon dioxide absorption and may lead to perioperative alterations in acid-base balance. Serum bicarbonate (HCO₃-) plays a central role in metabolic compensation; however, the clinical relevance of perioperative bicarbonate changes remains insufficiently defined.\n\nThis prospective observational study aims to evaluate the association between pneumoperitoneum duration and perioperative serum bicarbonate change (ΔHCO₃-), and to investigate whether ΔHCO₃- is associated with early discharge readiness at 48 hours (DR-48) following laparoscopic bariatric surgery. Patients undergoing laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass will be enrolled consecutively. No alteration of routine clinical care will occur.",[50],"Acid Base Disorder","NOT_YET_RECRUITING","2026-02-25",{"date":54,"type":55},"2026-03-03","ACTUAL",{"date":57,"type":46},"2026-03-01",{"date":59,"type":46},"2026-05-15",{"name":5,"class":6},1]