[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563278":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":28,"locations":38,"responsibleParty":56,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":10,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":10,"enrollmentInfo":69,"targetDuration":72,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":79,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Azienda Ospedaliero, Universitaria Pisana","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A",null,"Eligible patients with CPIRO 0-2",[13],"Diagnostic Test: serum calprotectin",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B","Eligible patients with CPIRO \\>3",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Group C","Control group (elective surgical patients without any source of intra-abdominal infection)",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"DIAGNOSTIC_TEST","serum calprotectin","A blood sample is collected at time of admission to detect serum level of calprotectin",[9,15,19],[29,34],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"SIlvia Strambi, MD","CONTACT","+393334905867","silvia.strambi@phd.unipi.it",{"name":35,"role":31,"phone":36,"phoneExt":10,"email":37},"Laura Caponi, MD","+393287852635","laura.caponi@unipi.it",[39],{"facility":40,"status":41,"city":42,"state":10,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Azienda Ospedaliero Universitaria Pisana (AOUP)","RECRUITING","Pisa","56126","Italy","IT",{"type":47,"coordinates":48},"Point",[49,50],10.4036,43.70853,{"lat":50,"lon":49},[53],{"name":54,"role":31,"phone":55,"phoneExt":10,"email":33},"Silvia Strambi, MD","+39050996085",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dario Tartaglia","dr","100563278","serum-calprotectin-in-surgical-septic-patients-100563278",false,"NCT06614088","Serum Calprotectin in Surgical Septic Patients","Serum Calprotectin in Surgical Septic Patients as an Early Predictor of Clinical Severity and Mortality: a Prospective Comparative Study.","Inclusion Criteria:\n\n* diagnosis of upper\u002Flower gastro-intestinal perforation\n* diagnosis of intestinal occlusion\n* diagnosis of acute cholecystitis\n* diagnosis of complicated acute appendicitis\n* radiological diagnosis of intra-abdominal sepsis\n\nExclusion Criteria:\n\n* recent (\\\u003C3 months) surgery\n* recent (\\\u003C3 months) trauma\n* diagnosis of acute pancreatitis\n* diagnosis of burn","ALL","18 Years",{"count":70,"type":71},150,"ESTIMATED","6 Months","OBSERVATIONAL","To early evaluate the serum levels of calprotectin in patients suffering from intra-abdominal sepsis requiring a surgical treatment. The research project aims to investigate the role of serum calprotectin in the diagnosis of sepsis and to establish whether its level significantly correlates with different degree of disease severity and with short and long-term outcomes. If these associations were confirmed, serum calprotectin would represent an easily and rapidly detectable biomarker able to predict the severity of sepsis.",[76,77,78],"Infection, Intraabdominal","Sepsis Abdominal","Biomarker",[80,81],"Serum calprotectin","Surgical infections","2024-09-24",{"date":84,"type":85},"2024-09-26","ACTUAL",{"date":87,"type":85},"2021-11-01",{"date":89,"type":71},"2025-01-01",{"name":5,"class":6},1]