[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632889":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":23,"locations":10,"responsibleParty":28,"collaborators":31,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":39,"eligibilityCriteria":40,"healthyVolunteers":41,"sex":42,"minAge":43,"maxAge":44,"enrollmentInfo":45,"targetDuration":10,"studyType":48,"phases":10,"briefSummary":49,"conditions":50,"keywords":10,"overallStatus":52,"whyStopped":10,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":10},{"fullName":5,"class":6},"Kanuni Sultan Suleyman Training and Research Hospital","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Normal BMD",null,"Postmenopausal women with normal bone mineral density based on dual-energy X-ray absorptiometry (DEXA) T-scores.",{"label":13,"type":10,"description":14,"interventionNames":10},"Osteopenia","Postmenopausal women with osteopenia defined by dual-energy X-ray absorptiometry (DEXA) T-scores.",{"label":16,"type":10,"description":17,"interventionNames":10},"Osteoporosis","Postmenopausal women with osteoporosis defined by dual-energy X-ray absorptiometry (DEXA) T-scores.",[19],{"name":20,"affiliation":21,"role":22},"Zeynep Karakuzu Güngör, M.D","Saglik Bilimleri Universitesi","PRINCIPAL_INVESTIGATOR",[24],{"name":20,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","+905077750375","zeynepkarakuzu@hotmail.com.tr",{"type":22,"investigatorFullName":29,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Zeynep Karakuzu Güngör","Specialist in Physical Medicine and Rehabilitation",[32],{"name":21,"class":6},"100632889","serum-myostatin-and-irisin-levels-in-postmenopausal-women-association-with-bone-mineral-density-and-muscle-strength-100632889",false,"NCT07519551","Serum Myostatin and Irisin Levels in Postmenopausal Women: Association With Bone Mineral Density and Muscle Strength","Evaluation of the Relationship Between Serum Myostatin and Irisin Levels and Bone Mineral Density and Muscle Strength in Postmenopausal Women","MYOIRISIN","Inclusion Criteria:\n\n* Postmenopausal women aged between 50 and 65 years Availability of bone mineral density measurement by dual-energy X-ray absorptiometry (DEXA) Willingness to participate in the study\n\nExclusion Criteria:\n\n* Presence of malignancy Chronic kidney disease Chronic liver disease Neuromuscular disorders Recent major surgery or trauma Use of medications affecting bone or muscle metabolism",true,"FEMALE","50 Years","65 Years",{"count":46,"type":47},60,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the relationship between serum myostatin and irisin levels and bone mineral density and muscle strength in postmenopausal women. Participants will be grouped according to bone mineral density as normal, osteopenic, or osteoporotic. Serum myostatin and irisin levels will be measured, and muscle strength will be assessed using handgrip strength and the five times sit-to-stand test. The associations between biochemical and functional parameters will be analyzed.",[51],"Osteoporosis, Osteopenia","NOT_YET_RECRUITING","2026-04-02",{"date":55,"type":56},"2026-04-09","ACTUAL",{"date":58,"type":47},"2026-04-03",{"date":60,"type":47},"2026-05-30",{"name":5,"class":6}]