[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628376":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":10,"responsibleParty":21,"collaborators":10,"id":24,"slug":25,"hasResults":26,"nctId":27,"briefTitle":28,"officialTitle":29,"acronym":10,"eligibilityCriteria":30,"healthyVolunteers":26,"sex":31,"minAge":32,"maxAge":33,"enrollmentInfo":34,"targetDuration":37,"studyType":38,"phases":10,"briefSummary":39,"conditions":40,"keywords":10,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":10},{"fullName":5,"class":6},"Konya Necmettin Erbakan Üniversitesi","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Cohort 1 - Primary Headache (Cases)",null,"Adolescents 12-18 years, ICHD-3 primary headache, verified by pediatric neurologist.",{"label":13,"type":10,"description":14,"interventionNames":10},"Cohort 2 - Controls","Age-\u002Fsex-matched adolescents from general pediatrics without recurrent headaches or chronic medical\u002Fpsychiatric disorders.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Fatma SARGIN, M.D","CONTACT","0905337263229","fatmasargin@yahoo.com.tr",{"type":22,"investigatorFullName":17,"investigatorTitle":23,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","M.D","100628376","serum-uric-acid-in-adolescents-with-primary-headache-a-case-control-study-100628376",false,"NCT07460830","Serum Uric Acid in Adolescents With Primary Headache: A Case-Control Study","Association Between Serum Uric Acid Levels and Primary Headaches in Adolescents: A Case-Control Study","Inclusion Criteria:\n\n* Inclusion Criteria (Cases):\n\nAdolescents aged 12-18 years presenting to pediatric neurology outpatient clinics\n\nDiagnosis of primary headache according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) (e.g., 1.1, 1.2, etc.)\n\nDiagnosis confirmed by a pediatric neurologist following a comprehensive clinical evaluation\n\nSufficient cognitive ability to understand and complete study instruments\n\n* Inclusion Criteria (Controls):\n\nAdolescents aged 12-18 years presenting to general pediatric outpatient clinics\n\nNo history of recurrent headaches\n\nNo chronic medical or psychiatric disorders\n\nMatched with the case group for age and sex\n\nExclusion Criteria:\n\n* History of neurological disorders other than primary headache\n* Previously diagnosed psychiatric conditions\n* Autoimmune diseases, chronic infections, severe cardiac failure, metabolic or inflammatory disorders, obesity, or significant hepatic or renal impairment\n* Regular use of psychotropic medications or a history of polycythemia\n* Use of drugs known to affect uric acid metabolism within 2-4 weeks prior to enrollment\n* Cognitive or developmental disabilities limiting the ability to understand or complete study instruments","ALL","12 Years","18 Years",{"count":35,"type":36},80,"ESTIMATED","1 Day","OBSERVATIONAL","This observational, case-control study will evaluate differences in serum uric acid and related hematologic and biochemical parameters between adolescents (12-18 years) with primary headache and age-\u002Fsex-matched controls without recurrent headaches or chronic medical\u002Fpsychiatric disorders. Cases will meet International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria verified by a pediatric neurologist after comprehensive clinical assessment. The study will also collect sociodemographic data and anthropometrics to calculate BMI. Primary outcome is the between-group difference in serum uric acid levels at enrollment. Secondary outcomes include group differences in ferritin, creatinine, BUN, complete blood count indices (Hb, WBC, neutrophils, lymphocytes, platelets, MPV), and BMI.",[41],"Primary Headache Disorders","NOT_YET_RECRUITING","2026-03-04",{"date":45,"type":46},"2026-03-10","ACTUAL",{"date":48,"type":36},"2026-03-15",{"date":50,"type":36},"2026-05-15",{"name":5,"class":6}]