[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582641":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":18,"locations":27,"responsibleParty":49,"collaborators":51,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":86,"sex":92,"minAge":93,"maxAge":10,"enrollmentInfo":94,"targetDuration":10,"studyType":97,"phases":10,"briefSummary":98,"conditions":99,"keywords":104,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"Universität des Saarlandes","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Dispatch centre suspected stroke patients",null,"Patients with dispatch centre suspected acute stroke diagnosis, who therefore had a code stroke dispatch",{"label":13,"type":10,"description":14,"interventionNames":10},"Patients with EMS on scene suspected acute stroke diagnosis","Patients for which the EMS at the emergency side suspects an acute stroke diagnosis and deliver the EMS stroke protocol treatment.",{"label":16,"type":10,"description":17,"interventionNames":10},"Patients with hospital confirmed acute stroke diagnosis","Patient who received a final hospital diagnosis of stroke after full diagnostic work-up.",[19,24],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Silke Walter, Consultant Neurologist","CONTACT","+49-6841-1626515","silke.walter@uks.eu",{"name":25,"role":21,"phone":10,"phoneExt":10,"email":26},"Brittany Wells, Paramedic","brittany.wells@gcu.ac.uk",[28],{"facility":29,"status":30,"city":31,"state":10,"zip":10,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Saarland University","RECRUITING","Homburg","Germany","DE",{"type":35,"coordinates":36},"Point",[37,38],7.33867,49.32637,{"lat":38,"lon":37},[41,45],{"name":42,"role":21,"phone":43,"phoneExt":10,"email":44},"Klaus Fassbender, Professor of Neurology","+49 - 68 1 - 302 - 75027","klaus.fassbender@uks.eu",{"name":46,"role":21,"phone":47,"phoneExt":10,"email":48},"Monika Bachhuber, Master","+49 - 68 1 - 302 - 75026","Monika.Bachhuber@uks.eu",{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[52,55,57,59,61,63,65,67,69,71,73,75,77,79,82],{"name":53,"class":54},"East of England Ambulance Service NHS Trust","OTHER_GOV",{"name":56,"class":6},"Norwegian Air Ambulance Foundation",{"name":58,"class":6},"Glasgow Caledonian University",{"name":60,"class":6},"Assiut University",{"name":62,"class":6},"The George Institute",{"name":64,"class":6},"Hospital de Clinicas de Porto Alegre",{"name":66,"class":6},"Hospital Israelita Albert Einstein",{"name":68,"class":6},"University Of Perugia",{"name":70,"class":6},"Ss. Cyril and Methodius University of Skopje",{"name":72,"class":54},"115 People's Hospital",{"name":74,"class":6},"Selcuk University",{"name":76,"class":6},"Copenhagen University Hospital, Denmark",{"name":78,"class":6},"National University Hospital, Singapore",{"name":80,"class":81},"Kwame Nkrumah University of Science and Technology, Ghana","UNKNOWN",{"name":83,"class":81},"Catholic University of Health and Allied Sciences, Mwanza, Tansania","100582641","sex-differences-in-prehospital-stroke-medicine-100582641",false,"NCT06865950","Sex diffErences in prehoSpitAl Stroke MEdicine","Sex Differences in Prehospital Acute Management of Suspected Stroke Patients","SESAME","Inclusion Criteria:\n\n* For all participants:\n* Adults aged 18 years of age and older\n* Emergency call to the national emergency telephone number because of acute symptoms\n* EMS treatment\n\nFor cohort 1:\n\n\\- Working diagnosis of acute stroke or TIA raised by the emergency medical dispatch centre\n\nFor cohort 2:\n\n\\- Working diagnosis of acute stroke or TIA raised by the EMS personnel at the emergency site\n\nFor cohort 3:\n\n\\- Hospital confirmed diagnosis of acute stroke or TIA\n\nExclusion Criteria:\n\n* Patients, who have acute stroke symptoms but do not involve the EMS and make their way to hospital themselves","ALL","18 Years",{"count":95,"type":96},2000,"ESTIMATED","OBSERVATIONAL","Background: Stroke is a leading cause for individual, family and societal harm with huge health-economic impact. Immediate and correct prehospital acute stroke pathway initiation is key for treatment success.\n\nEvidence points towards sex inequity in management pathways of acute stroke care. A complicating factor in acute stroke management is the diversity in clinical presentation among patients of different sex. This increases the challenges of correct prehospital identification.\n\nMost of the currently available data on male and female differences in acute stroke management come from patients with hospital-confirmed stroke. Little to no information is available about sex-related management differences of patients with prehospital suspected stroke, often missed by stroke quality databases.\n\nObjectives: To identify sex differences in EMS-delivered prehospital diagnostic accuracy and management of patients with suspected or confirmed acute stroke.\n\nMethods: International project collaboration to conduct a cross-regional cohort analysis of patients with a prehospital working diagnosis of stroke and\u002For hospital-confirmed stroke diagnosis.\n\nRelevance: More information and details about the reasons for a potential prehospital treatment inequity are a necessary next step for any improvement and subsequent development of structured training programmes for emergency medical service personnel. This project is the first large-scaled international collaboration addressing sex differences in prehospital stroke care. With this approach the project will not only lead to more urgently needed information, but will also serve as a lighthouse project for raising general awareness for this topic.",[100,101,102,103],"Stroke Acute","Emergency Medical Services","Sex Characteristics","Prehospital Setting",[105,106,107,108,109],"stroke","sex differences","ambulance service","stroke treatment","inequality","2025-05-15",{"date":112,"type":113},"2025-05-21","ACTUAL",{"date":115,"type":113},"2025-05-01",{"date":117,"type":96},"2026-12-31",{"name":5,"class":6},1]