[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100053994":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":10,"locations":25,"responsibleParty":50,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":10,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Washington University School of Medicine","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Postoperative patients",null,"Pediatric female patients undergoing a surgical procedure",[13,14],"Behavioral: Pain","Behavioral: Opioid use",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"BEHAVIORAL","Pain","Postoperative pain levels",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Opioid use","Postoperative opioid use",[9],[26],{"facility":5,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"RECRUITING","St Louis","Missouri","63110","United States","US",{"type":34,"coordinates":35},"Point",[36,37],-90.19789,38.62727,{"lat":37,"lon":36},[40,45,47],{"name":41,"role":42,"phone":43,"phoneExt":10,"email":44},"Alana McMichael, MA","CONTACT","314-273-6194","painlab@wustl.edu",{"name":46,"role":42,"phone":43,"phoneExt":10,"email":44},"Joel Brown",{"name":48,"role":49,"phone":10,"phoneExt":10,"email":10},"Hadas Nahman-Averbuch, PhD","PRINCIPAL_INVESTIGATOR",{"type":49,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Hadas Nahman-Averbuch","Asst Prof of Anesthesiology","100053994","sex-hormones-postoperative-pain-and-opioid-use-100053994",false,"NCT06023225","Sex Hormones, Postoperative Pain and Opioid Use","Relationship Between Sex Hormones, Postoperative Pain and Opioid Use: the Role of Immune Factors","SPO","Inclusion Criteria:\n\nPediatric female patients between the ages 11-16 undergoing an orthopedic (trauma and non-trauma) surgical procedure involving a long bone or joint, or the spine, English speaking\n\nExclusion Criteria:\n\nPregnancy; Diagnosis of chronic pain, Psychiatric, developmental or neurological disorders, Disorders that are associated with pubertal maturation (e.g., precocious puberty).","FEMALE","11 Years","16 Years",{"count":65,"type":66},210,"ESTIMATED","OBSERVATIONAL","Aim 1- To identify relationships between sex hormone levels and postoperative pain and opioid use.\n\nAim 2: To determine whether the effects of testosterone on postoperative pain and opioid use are mediated by immune factors",[70,71],"Postoperative Pain","Opioid Use","2026-07-10",{"date":74,"type":75},"2026-07-13","ACTUAL",{"date":77,"type":75},"2023-09-01",{"date":79,"type":66},"2029-07-01",{"name":5,"class":6},1]