[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605394":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":30,"collaborators":34,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":43,"sex":49,"minAge":50,"maxAge":7,"enrollmentInfo":51,"targetDuration":54,"studyType":55,"phases":7,"briefSummary":56,"conditions":57,"keywords":7,"overallStatus":16,"whyStopped":7,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"Shanghai General Hospital, China","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Yufan Wang, PhD","CONTACT","(+86) 021-63240090","yyffwang@sina.com",[15],{"facility":5,"status":16,"city":17,"state":18,"zip":19,"country":20,"countryCode":21,"cosmosGeoPoint":22,"geoPoint":27,"contacts":28},"RECRUITING","Shanghai","Shanghai Municipality","200080","China","CN",{"type":23,"coordinates":24},"Point",[25,26],121.45806,31.22222,{"lat":26,"lon":25},[29],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Yufan Wang","Chief Physician, Professor",[35,37,39],{"name":36,"class":6},"Shanghai Jiao Tong University Affiliated Sixth People's Hospital",{"name":38,"class":6},"Shanghai First Maternity and Infant Hospital",{"name":40,"class":6},"RenJi Hospital","100605394","shanghai-clinical-cohort-of-hyperglycemia-in-pregnancy-100605394",false,"NCT07161947","Shanghai Clinical Cohort of Hyperglycemia in Pregnancy","Shanghai Clinical Cohort-Hyperglycemia in Pregnancy (Reserved)","SHINE","Inclusion Criteria:\n\n* Pregnant individuals who provide written informed consent\n* At enrollment, meet one of the following:\n\n  1\\. Gestational diabetes mellitus (GDM) diagnosed by a 75-g oral glucose tolerance test (OGTT) using Chinese Diabetes Society (CDS) 2024 thresholds (any one of: fasting plasma glucose ≥5.1 mmol\u002FL, 1-h ≥10.0 mmol\u002FL, or 2-h ≥8.5 mmol\u002FL); or 2. Pre-gestational diabetes (type 1 or type 2) documented prior to pregnancy or meeting diabetes criteria at the first prenatal visit (e.g., fasting ≥7.0 mmol\u002FL, 2-h OGTT ≥11.1 mmol\u002FL, or HbA1c ≥6.5%); or 3. At high risk for GDM, defined a priori as ≥1 of the following: prior GDM; prior macrosomic infant (≥4,000 g); pre-pregnancy BMI ≥24 kg\u002Fm²; age ≥45 years; high-density lipoprotein cholesterol \\\u003C1 mmol\u002FL, and\u002For triglyceride levels \\>2.8 mmol\u002FL; first-degree family history of diabetes; polycystic ovary syndrome (PCOS); history of coronary heart disease; chronic hypertension and repeated positive fasting urinary glucose in early pregnancy\n* Age ≥18 years at the time of consent\n* Willing and able to attend postpartum assessments (OGTT at 6 weeks, 12 months, and annually thereafter), with planned follow-up ≥3 years\n\nExclusion Criteria:\n\n* Current or history of illicit drug use or substance abuse\n* Presence of an active infectious disease, including but not limited to: viral hepatitis, sexually transmitted infections or tuberculosis\n* Any other condition which, in the judgment of the investigator, would make the subject unsuitable for enrollment in the study","FEMALE","18 Years",{"count":52,"type":53},4000,"ESTIMATED","10 Years","OBSERVATIONAL","Establish a high-quality clinical cohort of hyperglycemia in pregnancy. Develop subtype-specific, end-to-end standards for diagnosis, treatment, and follow-up across the preconception, pregnancy, and postpartum phases. These standards will lay a solid foundation for efficient, high-quality clinical research.",[58,59],"Hyperglycemia in Pregnant Diabetic Patients","Gestatiaonl Diabetes Mellitus","2025-09-08",{"date":62,"type":63},"2025-09-09","ACTUAL",{"date":65,"type":63},"2025-04-01",{"date":67,"type":53},"2027-12-31",{"name":5,"class":6},1]