[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100366210":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":40,"responsibleParty":62,"collaborators":35,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":35,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":35,"enrollmentInfo":73,"targetDuration":35,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":35,"overallStatus":42,"whyStopped":35,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Balgrist University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"short antibiotic therapy","EXPERIMENTAL","3 weeks of antibiotic therapy with no implant left in place 6 weeks of antibiotic therapy with implant left in place",[13],"Drug: duration of standard antibiotic therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"long antibiotic therapy","ACTIVE_COMPARATOR","6 weeks of antibiotic therapy with no implant in place 12 weeks of antibiotic therapy with implant left in place",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","duration of standard antibiotic therapy","antibiotic therapy for spine infections. 3 vs 6 weeks if no implant left in place. 6 vs 12 weeks if implant left in place. The antibiotic agents used are officially indicated for orthopedic infections, including spine infections and available in Switzerland since decades. Standard dosing will be applied and only modified according to the patient's co-morbidities, intolerances and weight.",[15,9],[26],"Co-amoxiclav, vancomycin",[28],{"name":29,"affiliation":5,"role":30},"Ilker Uckay, PD Dr med","STUDY_DIRECTOR",[32,37],{"name":29,"role":33,"phone":34,"phoneExt":35,"email":36},"CONTACT","+41 44 386 1111",null,"ilker.uckay@balgrist.ch",{"name":38,"role":33,"phone":34,"phoneExt":35,"email":39},"Michael Betz, PD Dr med","michael.betz@balgrist.ch",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Zurich","Canton of Zurich","8008","Switzerland","CH",{"type":49,"coordinates":50},"Point",[51,52],8.55,47.36667,{"lat":52,"lon":51},[55,58],{"name":56,"role":33,"phone":57,"phoneExt":35,"email":36},"Ilker Uckay, MD","+41 44 386 37 05",{"name":59,"role":33,"phone":60,"phoneExt":35,"email":61},"Regula Schupbach","+41 44 510 73 75","regula.schuepbach@balgrist.ch",{"type":63,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR","100366210","short-post-surgical-antibiotic-therapy-in-spine-infections---a-prospective-randomized-unblinded-non-inferiority-trial-100366210",false,"NCT04048304","Short Post-surgical Antibiotic Therapy in Spine Infections - a Prospective, Randomized, Unblinded, Non-inferiority Trial","Short Post-surgical Antibiotic Therapy in Spine Infections - a Pro-spective, Randomized, Unblinded, Non-inferiority Trial","Inclusion Criteria:\n\n* Spine surgery and intraoperative debridement with any technique\n* At least 12 months of scheduled follow-up from hospitalization\n* Bacterial spine infection of any nature, independently of implants or co-morbidities\n\nExclusion Criteria:\n\n* Mycobacterial, fungal, nocardial, and Actinomyces infections in the spine\n* Non-resected cancer in the infection site\n* Bone marrow or recent solid organ transplant patient (Recent: \\\u003C5 years)\n* Any other infection in the patient requiring more than 6 weeks of antibiotic therapy\n* More than three intraoperative debridements performed for spine infection\n* Absence of at least one surgical intraoperative debridement of infection","ALL","18 Years",{"count":74,"type":75},236,"ESTIMATED","INTERVENTIONAL",[78],"NA","We implement a prospective, randomized, unblinded, non-inferiority trial regarding the duration of systemic, targeted antibiotic therapy after the first surgical debridement for spine infection; randomizing 1:1 between\n\n1. Six and twelve weeks of antibiotic therapy if there is an implant left in place\n2. Three and six weeks of antibiotic therapy if there is no implant left",[81],"Infection","2025-02-20",{"date":84,"type":85},"2025-02-21","ACTUAL",{"date":87,"type":85},"2019-07-31",{"date":89,"type":75},"2025-12-31",{"name":5,"class":6},1]