[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599268":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":46,"responsibleParty":68,"collaborators":26,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":26,"enrollmentInfo":80,"targetDuration":26,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":49,"whyStopped":26,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Saint-Joseph University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pacing Group","PLACEBO_COMPARATOR","Patients in this group receive continuous atrial pacing at 90 bpm during the first 24 postoperative hours (outside of evaluation sequences).",[13],"Procedure: Pacing Protocol for Pacing Group",{"label":15,"type":16,"description":17,"interventionNames":18},"Non-Pacing Group","ACTIVE_COMPARATOR","Patients in this group remain in their spontaneous sinus rhythm outside of the evaluation sequences.",[19],"Procedure: Pacing Protocol for Non-pacing Group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Pacing Protocol for Pacing Group","At four standardized time points (H0: arrival in the ICU, H6, H12, H24), a transient pacing sequence at 70, 80, and 90 bpm is conducted, with each rate applied for 10 minutes to allow stabilization, followed by recording of the hemodynamic profile and blood pressure, as follows:\n\n* If the patient has a spontaneous rhythm between 50 and 69 bpm, measurements are taken at the spontaneous rate, then at 70 bpm, 80 bpm, and finally 90 bpm\n* If the patient has a spontaneous rhythm between 70 and 79 bpm, measurements are taken at the spontaneous rate, then at 80 bpm, and finally at 90 bpm\n* If the patient has a spontaneous rhythm between 80 and 89 bpm, measurements are taken at the spontaneous rate, then at 90 bpm\n* If the patient has a spontaneous rhythm ≥ 90 bpm, measurements are taken at the spontaneous rate only",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Pacing Protocol for Non-pacing Group","At H0, H6, H12, and H24, they will undergo transient pacing at 70, 80, and 90 bpm, following the same measurement protocol (10 minutes per rate), followed by recording of the hemodynamic profile and blood pressure, as follows:\n\n* If the patient has a rhythm between 50 and 69 bpm, measurements will be taken at the spontaneous rate, then at 70 bpm, 80 bpm, and finally 90 bpm\n* If the patient has a rhythm between 70 and 79 bpm, measurements will be taken at the spontaneous rate, then at 80 bpm, and finally at 90 bpm\n* If the patient has a rhythm between 80 and 89 bpm, measurements will be taken at the spontaneous rate, then at 90 bpm\n* If the patient has a rhythm ≥ 90 bpm, measurements will be taken at the spontaneous rate only\n\nOutside the pacing periods at different rates, patients in the non-pacing group will remain on their spontaneous sinus rhythm.",[15],[32],{"name":33,"affiliation":34,"role":35},"Samia Jebara","Saint Joseph University of Beirut","STUDY_CHAIR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Rhea Mattar","CONTACT","+96171464840","rhea.mattar@net.usj.edu.lb",{"name":43,"role":39,"phone":44,"phoneExt":26,"email":45},"Joanna Tohme","+96170492735","joanna.tohme1@usj.edu.lb",[47],{"facility":48,"status":49,"city":50,"state":26,"zip":26,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Department of Anesthesia and Critical Care, Hôtel-Dieu de France Hospital","RECRUITING","Beirut","Lebanon","LB",{"type":54,"coordinates":55},"Point",[56,57],35.50157,33.89332,{"lat":57,"lon":56},[60,61,62,64,65],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},{"name":43,"role":39,"phone":44,"phoneExt":26,"email":45},{"name":43,"role":63,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"name":38,"role":63,"phone":26,"phoneExt":26,"email":26},{"name":66,"role":67,"phone":26,"phoneExt":26,"email":26},"Amine Fikani","SUB_INVESTIGATOR",{"type":63,"investigatorFullName":43,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"MD, MSc","100599268","short-term-atrial-pacing-and-hemodynamics-after-cardiac-surgery-100599268",false,"NCT07082283","Short-Term Atrial Pacing and Hemodynamics After Cardiac Surgery","STAPH-CS Study: Short-Term Atrial Pacing and Hemodynamics After Cardiac Surgery - A Prospective Randomized Evaluation of Variable-Rate Atrial Stimulation After Cardiac Surgery With Cardiopulmonary Bypass","STAPH-CS","Inclusion Criteria:\n\n* Patients aged 18 years or older\n* Cardiac surgery under CPB (coronary artery bypass grafting, valve replacement or repair, or combined procedures)\n* Placement of epicardial atrioventricular pacing wires during surgery\n* Placement of a Swan-Ganz catheter intraoperatively\n* Signed informed consent\n\nExclusion Criteria:\n\n* Emergency surgery\n* Patients with an internal pacemaker\n* History of permanent atrial fibrillation\n* Complete atrioventricular block upon weaning from CPB\n* Junctional rhythm upon weaning from CPB\n* Sinus rhythm \\\u003C 50 bpm upon weaning from CPB\n* Failure of atrial or dual-chamber pacing (patients paced in ventricular mode VVI)\n* Contraindication to Swan-Ganz catheter placement\n* Hemodynamic instability defined by significant bleeding or tamponade requiring surgical re-intervention, or the need for escalating doses of vasopressors (Norepinephrine \\> 1 μg\u002Fkg\u002Fmin, Dobutamine \\> 10 μg\u002Fkg\u002Fmin)","ALL","18 Years",{"count":81,"type":82},200,"ESTIMATED","INTERVENTIONAL",[85],"NA","The goal of this clinical trial is to learn whether temporary atrial pacing improves heart function after cardiac surgery under cardiopulmonary bypass (CPB). It will also help determine the best pacing rate during the first 24 hours after surgery. The main questions it aims to answer are:\n\n* Does atrial pacing improve cardiac output after surgery?\n* Is 70, 80, or 90 bpm the most effective pacing rate?\n* Does pacing reduce the risk of atrial fibrillation after surgery?",[88],"Cardiac Output",[90,91,92,93,94],"Cardiopulmonary bypass","Temporary atrial pacing","Pacing frequency","Hemodynamic profile","Cardiac output","2025-08-15",{"date":97,"type":98},"2025-08-17","ACTUAL",{"date":100,"type":98},"2025-08-04",{"date":102,"type":82},"2026-09-30",{"name":5,"class":6},1]