[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100480625":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":33,"locations":43,"responsibleParty":62,"collaborators":10,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":10,"eligibilityCriteria":71,"healthyVolunteers":68,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":10,"studyType":78,"phases":10,"briefSummary":79,"conditions":80,"keywords":10,"overallStatus":46,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University Medical Center Groningen","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Open PLIF",null,"Patients undergoing conventional open posterior lumbar interbody fusion (PLIF) surgery. A long midline skin incision (10-15 cm) is made, after which the paravertebral muscles are detached from the midline and retracted laterally in order to expose the facet joints and pedicle entry point. After the pedicle screws are positioned, the disc will be removed bilaterally and packed with autogenous bone chips, followed by bilateral placement of polyetheretherketone (PEEK) PLIF cages.",[13],"Procedure: Posterior Lumbar Interbody Fusion (PLIF)",{"label":15,"type":10,"description":16,"interventionNames":17},"CBT-PLIF","Patient undergoing minimal access PLIF surgery with cortical bone trajectory (CBT-PLIF). The CBT-PLIF uses more medialized entry points, closer to the spinal process. Due to the medial approach of this technique, a smaller incision is needed and the need to retract muscles laterally is minimalized.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"MI-PLIF","Patients undergoing minimal invasive PLIF surgery. A small midline incision (3-5 cm) will be made to perform mini-open decompression and placement of bilateral PEEK PLIF cages. In addition, two small paramedian incisions will be made on both sides for percutaneous pedicle screw fixation.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"PROCEDURE","Posterior Lumbar Interbody Fusion (PLIF)","Spinal fusion in the lumbar spine by inserting a cage directly into the disc space. This is an observational study in which the standard procedure\u002Fcare is followed.",[15,19,9],[29],{"name":30,"affiliation":31,"role":32},"Jos M.A. Kuijlen, MD, PhD","University Medical Centre Groningen (UMCG), Hanzeplein 1, 9713GZ Groningen","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Diane H. Steenks","CONTACT","050 3617976","d.h.steenks@umcg.nl",{"name":40,"role":36,"phone":41,"phoneExt":10,"email":42},"Hui Ling Li, BsC","0629249620","h.l.li@umcg.nl",[44],{"facility":45,"status":46,"city":47,"state":10,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"UMCG","RECRUITING","Groningen","9713 GZ","Netherlands","NL",{"type":52,"coordinates":53},"Point",[54,55],6.56667,53.21917,{"lat":55,"lon":54},[58],{"name":59,"role":36,"phone":60,"phoneExt":10,"email":61},"Jos MA Kuijlen, MD\u002FPHD","050 361 2837","jmakuijlen@umcg.nl",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Jos M. A. Kuijlen","Dr. MD, PhD","100480625","short-term-clinical-outcome-of-cortical-bone-trajectory-compared-with-the-traditional-open-and-minimal-invasive-posterior-lumbar-interbody-fusion-100480625",false,"NCT05538416","Short-term Clinical Outcome of Cortical Bone Trajectory Compared With the Traditional \"Open\" and Minimal Invasive Posterior Lumbar Interbody Fusion","Inclusion Criteria:\n\n* 18-75 years\n* Degenerative or spondylolytic spondylolisthesis\n* Neurogenic claudication and\u002For radicular leg pain\n* Low grade (Meyerding grade l and ll)\n* Persistent complaints for over 3 months\n\nExclusion Criteria:\n\n* Previous spine fusion surgery at the same level\n* Osteoporosis\n* Active infection or prior infection at the surgical site\n* Active cancer\n* Spondylolisthesis grade lll or greater\n* More than one symptomatic level that needs fusion\n* Pregnancy\n* Contraindication for surgery\n* Severe mental or psychiatric disorder\n* Substance abuse\n* Inadequate knowledge of Dutch language\n* Morbid obesity (body mass index \\>40)","ALL","18 Years","75 Years",{"count":76,"type":77},180,"ESTIMATED","OBSERVATIONAL","A combined prospective cohort study and retrospective analysis of previously collected data. Three different techniques for posterior lumbar interbody fusion (PLIF) are compared: CBT-PLIF, MI-PLIF and open PLIF. A total of 180 patients are included, who will be followed up to 6 weeks postoperatively.",[81,82],"Degenerative Spondylolisthesis","Spondylolytic Spondylolisthesis","2025-05-01",{"date":85,"type":86},"2025-05-04","ACTUAL",{"date":88,"type":86},"2022-09-19",{"date":90,"type":77},"2025-12",{"name":64,"class":6},1]