[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621759":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":27,"locations":37,"responsibleParty":63,"collaborators":67,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":10,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":10,"enrollmentInfo":80,"targetDuration":10,"studyType":83,"phases":10,"briefSummary":84,"conditions":85,"keywords":90,"overallStatus":93,"whyStopped":10,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"University of Maryland, Baltimore","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Study Population 1",null,"This study population will consist of individuals who have a diagnosis of breast cancer and have not received chemotherapy treatment for their breast cancer. Individuals who have received surgical resection and\u002For radiation therapy and\u002For endocrine therapy for their breast cancer will be included.",[13],"Other: Epigenetic Assay",{"label":15,"type":10,"description":16,"interventionNames":17},"Study Population 2","This study population will consist of individuals who have a diagnosis of breast cancer and have received chemotherapy treatment for their breast cancer. All stages of breast cancer will be included including individuals in remission.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Study Population 3","This study population will consist of individuals who are at high risk of developing breast cancer.",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Epigenetic Assay","Up to 15 ml of blood will be collected from each patient at various time points throughout their 5 years of participation. DNA extraction, bisulfite conversion and analysis of epigenetic markers through PCR or next-generation sequencing will be performed. An epigenetic signature assay will then be identified.",[9,15,19],[28,33],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Jennifer Emel, MA","CONTACT","410-553-8048","Jennifer.Emel@umm.edu",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Sade Bademosi","410-553-8188","Sade.Bademosi@umm.edu",[38],{"facility":39,"status":10,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"University of Maryland Baltimore Washington Medical Center","Glen Burnie","Maryland","21061","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-76.62469,39.16261,{"lat":49,"lon":48},[52,56,59,61],{"name":53,"role":30,"phone":54,"phoneExt":10,"email":55},"Peter Olivieri, MD","410-553-8241","polivieri@umm.edu",{"name":57,"role":58,"phone":10,"phoneExt":10,"email":10},"Cynthia Drogula, MD","SUB_INVESTIGATOR",{"name":60,"role":58,"phone":10,"phoneExt":10,"email":10},"Jeffrey Marshall, MD",{"name":62,"role":58,"phone":10,"phoneExt":10,"email":10},"Harvinder Singh, MD",{"type":64,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Peter Olivieri","Chair, Division of Pulmonary & Critical Care; Director, Interventional Pulmonary Program",[68],{"name":69,"class":70},"EPOCH Epigenetics, Inc","UNKNOWN","100621759","signature-development-and-validation-protocol-for-an-epigenetic-assay-in-diagnosing-breast-cancer-100621759",false,"NCT07374796","Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Breast Cancer","Inclusion Criteria:\n\n* 18 years old or older\n* Patient of UMMS\n* Willing and able to consent to study procedures listed in the protocol\n* Ability to speak and understand English\n\nExclusion Criteria:\n\n* Younger than 18 years old\n* Patient not cared for at UMMS\n* Unable to consent to study procedures listed in the protocol\n* Unable to speak or understand English",true,"ALL","18 Years",{"count":81,"type":82},450,"ESTIMATED","OBSERVATIONAL","The purpose of this research study is to test a new process for diagnosing breast cancer by examining changes to your DNA that can be detected from a blood test. The information we learn by doing this study could potentially help people in the future.\n\nParticipants in this study will have blood samples collected, have their medical records reviewed by study personnel and fill out questionnaires at different time points during the study. Blood sample collection will occur during normal routine clinic visits. Participation in this study will last approximately 5 years.",[86,87,88,89],"Breast Cancer (Locally Advanced or Metastatic)","Healthy Volunteers (HV)","Unhealthy Volunteers","Breast Cancer Screening",[91,89,92,88],"Breast Cancer","Healthy Volunteers","NOT_YET_RECRUITING","2026-04-21",{"date":96,"type":97},"2026-04-22","ACTUAL",{"date":99,"type":82},"2026-06-01",{"date":101,"type":82},"2032-07",{"name":5,"class":6},1]