[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627500":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":47,"responsibleParty":64,"collaborators":43,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":43,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":43,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":43,"overallStatus":49,"whyStopped":43,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Poznan University of Medical Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sham blocks","PLACEBO_COMPARATOR","iPACK block with 20ml of 0.9% sodium chloride and ACB with 20ml of 0.9% sodium chloride",[13],"Drug: sodium Chloride",{"label":15,"type":16,"description":17,"interventionNames":18},"iPACK block with ACB","ACTIVE_COMPARATOR","iPACK block with 20ml of 0.2% ropivacaine and ACB with 20ml of 0.2% ropivacaine",[19],"Drug: Ropivacaine Hydrocloride",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","sodium Chloride","After spinal anesthesia, the ultrasound-guided iPACK block will be performed with 20ml of 0.9% sodium chloride; and Adductor Canal Block will be performed with 20ml of 0.9% sodium chloride",[9],[27],"0.9% NaCl",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Ropivacaine Hydrocloride","After spinal anesthesia, the ultrasound-guided iPACK block will be performed with 20ml of 0.2% ropivacaine, and the Adductor Canal Block will be performed with 20ml of 0.2% ropivacaine",[15],[33],"0.2% ropivacaine",[35],{"name":36,"affiliation":37,"role":38},"Malgorzata Reysner, MD PhD","Poznań University of Medical Sciences","STUDY_CHAIR",[40,45],{"name":36,"role":41,"phone":42,"phoneExt":43,"email":44},"CONTACT","+48 501 056 924",null,"mreysner@ump.edu.pl",{"name":36,"role":41,"phone":46,"phoneExt":43,"email":44},"+48 61 83 10 122",[48],{"facility":5,"status":49,"city":50,"state":43,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Poznan","62-701","Poland","PL",{"type":55,"coordinates":56},"Point",[57,58],16.92993,52.40692,{"lat":58,"lon":57},[61],{"name":62,"role":41,"phone":63,"phoneExt":43,"email":44},"Malgorzata Reysner, M.D. Ph.D.","+48 61 873 83 03",{"type":65,"investigatorFullName":43,"investigatorTitle":43,"investigatorAffiliation":43,"oldNameTitle":43,"oldOrganization":43},"SPONSOR","100627500","sii-levels-following-ipack-block-with-adductor-canal-block-in-knee-arthroplasty-100627500",false,"NCT07449442","SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty","iPACK Block With Adductor Canal Block Mitigates Surgical Stress and Enhances Analgesia in Total Hip Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients with ASA classification I-III\n* Aged 65-100 years\n* Who will be scheduled for hip arthroplasty under spinal anesthesia\n\nExclusion Criteria:\n\n* Patients who have a history of bleeding diathesis\n* Take anticoagulant therapy\n* History of chronic pain before surgery\n* Multiple trauma\n* patients unable to assess their pain (dementia)\n* patients operated under general anesthesia\n* patients having an infection in the region of the procedure\n* the patient who does not accept the procedure","ALL","65 Years","100 Years",{"count":77,"type":78},60,"ESTIMATED","INTERVENTIONAL",[81],"NA","This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal anesthesia. SII, calculated as platelet × neutrophil \u002F lymphocyte count, is used as a composite marker of perioperative inflammatory and immune response. The study investigates whether iPACK block with ACB attenuates the systemic inflammatory reaction to surgical trauma compared to sham block.",[84],"Knee Osteoarthritis","2026-05-20",{"date":87,"type":88},"2026-05-22","ACTUAL",{"date":90,"type":88},"2026-03-01",{"date":92,"type":78},"2026-06-30",{"name":5,"class":6},1]