[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638438":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":48,"responsibleParty":60,"collaborators":43,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":43,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":43,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":43,"overallStatus":81,"whyStopped":43,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Poznan University of Medical Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Spinal Anesthesia Alone (Control)","SHAM_COMPARATOR","Participants will receive standardized spinal anesthesia according to institutional protocol. A sham procedure will be performed to maintain blinding. Postoperative analgesia will be standardized in all participants.",[13],"Drug: 0.9%NaCl",{"label":15,"type":16,"description":17,"interventionNames":18},"Spinal Anesthesia + PENG Block","ACTIVE_COMPARATOR","Participants will receive standardized spinal anesthesia combined with ultrasound-guided pericapsular nerve group (PENG) block using a local anesthetic (e.g., ropivacaine 0.2%). Postoperative analgesia will be standardized in all participants.",[19],"Drug: Ropivacaine 0.2% Injectable Solution",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Ropivacaine 0.2% Injectable Solution","Ultrasound-guided regional anesthesia technique targeting the articular branches of the hip joint to provide postoperative analgesia.",[15],[27],"PENG block",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"0.9%NaCl","Simulated procedure performed to maintain blinding without administration of local anesthetic.",[9],[33],"Sham Procedure",[35],{"name":36,"affiliation":37,"role":38},"Małgorzata Reysner, MD PhD","Poznań University of Medical Sciences","STUDY_CHAIR",[40,45],{"name":36,"role":41,"phone":42,"phoneExt":43,"email":44},"CONTACT","+48 (61) 831-01-22",null,"mreysner@ump.edu.pl",{"name":46,"role":41,"phone":43,"phoneExt":43,"email":47},"Tomasz Reysner, MD PhD","treysner@ump.edu.pl",[49],{"facility":5,"status":43,"city":50,"state":43,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":43},"Poznan","62-701","Poland","PL",{"type":55,"coordinates":56},"Point",[57,58],16.92993,52.40692,{"lat":58,"lon":57},{"type":61,"investigatorFullName":43,"investigatorTitle":43,"investigatorAffiliation":43,"oldNameTitle":43,"oldOrganization":43},"SPONSOR","100638438","sii-levels-following-peng-block-in-pediatric-hip-surgery-100638438",false,"NCT07607535","SII Levels Following PENG Block in Pediatric Hip Surgery","Pericapsular Nerve Group Block Mitigates Surgical Stress and Enhances Analgesia in Pediatric Hip Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 3-8 years\n* Scheduled for elective unilateral hip surgery\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Written informed consent from the parent or legal guardian\n\nExclusion Criteria:\n\n* Contraindications to spinal anesthesia or PENG block\n* Infection at the planned needle insertion site\n* Coagulation disorders\n* Chronic immunosuppressive therapy or chronic steroid use\n* Active infection or inflammatory disease\n* Ongoing oncological treatment\n* Known allergy to local anesthetics or study-related medications\n* Conversion to general anesthesia\n* Refusal to participate","ALL","3 Years","8 Years",{"count":73,"type":74},100,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study is a prospective, randomized, double-blind clinical trial. Its aim is to evaluate whether adding a pericapsular nerve group (PENG) block to spinal anesthesia can reduce the inflammatory response after hip surgery in children.\n\nHip surgery in children can cause a strong stress and inflammatory reaction, which may affect pain after surgery, the need for opioid medications, and recovery.\n\nChildren aged 3 to 8 years will be randomly assigned to one of two groups: spinal anesthesia alone or spinal anesthesia combined with a PENG block. The main goal is to compare changes in the Systemic Immune-Inflammation Index (SII), a blood-based marker of inflammation, measured before surgery and 24 hours after surgery.\n\nAdditional outcomes include other inflammatory markers, postoperative pain, opioid use, time to first rescue pain medication, and side effects.",[80],"Hip Dysplasia","NOT_YET_RECRUITING","2026-05-20",{"date":84,"type":85},"2026-05-26","ACTUAL",{"date":87,"type":74},"2026-06-01",{"date":89,"type":74},"2027-08-31",{"name":5,"class":6},1]