[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606001":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":20,"locations":26,"responsibleParty":42,"collaborators":11,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":11,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":11,"enrollmentInfo":54,"targetDuration":11,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":69,"whyStopped":11,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"RenJi Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Group with surgical glove compression applied to the dominant hand","EXPERIMENTAL",null,[13],"Procedure: Simple Surgical Glove Compression Technique",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"PROCEDURE","Simple Surgical Glove Compression Technique","Patients will wear surgical gloves of smaller size than the patient's hand, on the dominant hand from 15 minutes before the start of each neoadjuvant chemotherapy infusion until 15 minutes after the end of infusion (total of 90 minutes). The non-dominant hand will serve as the untreated control.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":11,"email":25},"Jinsong Lu, M.D.","CONTACT","86(21)68385569","lujingsong@renji.com",[27],{"facility":28,"status":11,"city":29,"state":11,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Renji Hospital, School of Medicine, Shanghai Jiaotong University","Shanghai","200127","China","CN",{"type":34,"coordinates":35},"Point",[36,37],121.45806,31.22222,{"lat":37,"lon":36},[40],{"name":41,"role":23,"phone":24,"phoneExt":11,"email":25},"Jinsong Lu",{"type":43,"investigatorFullName":41,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Chief of Department of Breast Surgery","100606001","simple-surgical-glove-compression-to-prevent-chemotherapy-induced-peripheral-neuropathy-100606001",false,"NCT07169864","Simple Surgical Glove Compression to Prevent Chemotherapy-Induced Peripheral Neuropathy","An Exploratory Self-Controlled Study on the Preventive Effect of the Simple Surgical Glove Compression Technique Against Chemotherapy-Induced Peripheral Neuropathy","Inclusion Criteria:\n\n* Age ≥ 18 years;\n* Histologically confirmed primary invasive breast cancer;\n* Planned to receive ≥ 8 weeks of weekly neoadjuvant chemotherapy (utidelone plus cisplatin);\n* ECOG performance status: 0-1;\n\nExclusion Criteria:\n\n* Distant metastasis;\n* Presence of sensory or motor neurological disorders, or symptoms related to peripheral neuropathy with CTCAE grade ≥ 2, or currently receiving medication for peripheral neuropathy;\n* Conditions affecting limb function;\n* Known allergy to glove materials (e.g., latex)","ALL","18 Years",{"count":55,"type":56},44,"ESTIMATED","INTERVENTIONAL",[59],"NA","To evaluate the preventive efficacy of a simple surgical glove compression technique in reducing the incidence and severity of Chemotherapy Induced Peripheral Neuropathy among patients receiving chemotherapy.",[62,63,64],"Breast Cancer","Chemotherapy Induced Peripheral Neuropathy (CIPN)","Neoadjuvant Therapy",[66,67,68],"Utidelone","CIPN","Neoadjuvant chemotherapy","NOT_YET_RECRUITING","2025-09-11",{"date":72,"type":73},"2025-09-12","ACTUAL",{"date":75,"type":56},"2025-09-15",{"date":77,"type":56},"2027-12-31",{"name":41,"class":6},1]