[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631915":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":26,"locations":34,"responsibleParty":103,"collaborators":105,"id":118,"slug":119,"hasResults":120,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":124,"eligibilityCriteria":125,"healthyVolunteers":120,"sex":126,"minAge":127,"maxAge":10,"enrollmentInfo":128,"targetDuration":131,"studyType":132,"phases":10,"briefSummary":133,"conditions":134,"keywords":10,"overallStatus":141,"whyStopped":10,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":151},{"fullName":5,"class":6},"Linkoeping University","OTHER_GOV",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"Primary objective cohort - Lung cancer lobectomy",null,"For primary objective, patients undergoing lobectomy for lung cancer will be studied.",{"label":13,"type":10,"description":14,"interventionNames":10},"Neoadjuvant treatment cohort","As one secondary objective, patients with lung cancer undergoing neoadjuvant treatment before surgery or other non-surgical treatment will be studied separately",{"label":16,"type":10,"description":17,"interventionNames":10},"Sub-lobular resection cohort","As one secondary objective, patients undergoing sublobular resection for lung cancer will be studied separately.",{"label":19,"type":10,"description":20,"interventionNames":10},"Non-surgical treatment cohort","As one secondary objective, patients undergoing other treatment than surgery for lung cancer will be studied.",[22],{"name":23,"affiliation":24,"role":25},"Kristofer Hedman, MD, PhD","Department of Medical, Health and Caring Sciences, Linkoping University, Linkoping, Sweden","PRINCIPAL_INVESTIGATOR",[27,31],{"name":23,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","+46 10 1033356","kristofer.hedman@liu.se",{"name":32,"role":28,"phone":10,"phoneExt":10,"email":33},"Karolina Kristenson","karolina.kristenson@regionostergotland.se",[35,51,64,77,90],{"facility":36,"status":10,"city":37,"state":10,"zip":10,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Department of Pulmonology, Ryhov","Jönköping","Sweden","SE",{"type":41,"coordinates":42},"Point",[43,44],14.15618,57.78145,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":10,"email":50},"Magnus Kentson, MD, PhD","+ 46 10-241 00 00.","magnus.kentson@rjl.se",{"facility":52,"status":10,"city":53,"state":10,"zip":10,"country":38,"countryCode":39,"cosmosGeoPoint":54,"geoPoint":58,"contacts":59},"Department of Pulmonology, Kalmar County Hospital","Kalmar",{"type":41,"coordinates":55},[56,57],16.36163,56.66157,{"lat":57,"lon":56},[60],{"name":61,"role":28,"phone":62,"phoneExt":10,"email":63},"Niels Hornstra, MD","+46 10-358 00 00","Niels.Hornstra@regionkalmar.se",{"facility":65,"status":10,"city":66,"state":10,"zip":10,"country":38,"countryCode":39,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"Department of Pulmonology, Blekinge Hospital","Karlskrona",{"type":41,"coordinates":68},[69,70],15.58661,56.16156,{"lat":70,"lon":69},[73],{"name":74,"role":28,"phone":75,"phoneExt":10,"email":76},"Magnus Ekström, MD, PhD","+46 455-73 10 00","pmekstrom@gmail.com",{"facility":78,"status":10,"city":79,"state":10,"zip":10,"country":38,"countryCode":39,"cosmosGeoPoint":80,"geoPoint":84,"contacts":85},"Department of Pulmonology, University Hospital","Linköping",{"type":41,"coordinates":81},[82,83],15.62157,58.41086,{"lat":83,"lon":82},[86],{"name":87,"role":28,"phone":88,"phoneExt":10,"email":89},"Gabriel Högström, MD, PhD","+46 10 103 00 00","gabriel.hogstrom@regionostergotland.se",{"facility":91,"status":10,"city":92,"state":10,"zip":10,"country":38,"countryCode":39,"cosmosGeoPoint":93,"geoPoint":97,"contacts":98},"Department of Clinical Physiology","Lund",{"type":41,"coordinates":94},[95,96],13.19321,55.70584,{"lat":96,"lon":95},[99],{"name":100,"role":28,"phone":101,"phoneExt":10,"email":102},"Henrik Mosén, MD, PhD","+46 40-33 10 00","henrik.mosen@med.lu.se",{"type":25,"investigatorFullName":23,"investigatorTitle":104,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Senior Associate Professor",[106,109,111,114,116],{"name":107,"class":108},"Region Östergötland","OTHER",{"name":110,"class":108},"Region Skane",{"name":112,"class":113},"Region Kalmar län","UNKNOWN",{"name":115,"class":113},"Region Blekinge",{"name":117,"class":6},"Region Jönköping County","100631915","simplified-exercise-based-risk-assessment-in-lung-cancer-100631915",false,"NCT07506889","Simplified Exercise-based Risk Assessment in Lung Cancer","EXercise-based Evaluation of Ventilatory Efficiency for enHanced Risk Assessment in Lungcancer trEatment Using End-tidal CO2: a Multicenter, Prospective Study","EXHALE-CO2","Inclusion Criteria:\n\n* Lung Cancer Diagnosis\n* Age of at least 18 years\n\nExclusion Criteria:\n\n* Not able to perform cycle ergometer exercise\n* Not able to understand spoken or written Swedish","ALL","18 Years",{"count":129,"type":130},500,"ESTIMATED","1 Year","OBSERVATIONAL","Physiological evaluation is part of the preoperative risk estimation in patients with lung cancer, and it aids in the choice of treatment. Ventilatory efficiency during exercise has emerged as a strong predictor of major postoperative complications, so far determined during a maximal cardiopulmonary exercise test. However, this test is limited by its availability and high cost, due to the requirement of high-technological equipment and advanced expertise. The current project aims to evaluate a simplified and accessible method for risk evaluation before decision on treatment in lung cancer. It builds on recent advances in technology and knowledge and combines a simple, low-intensity cycling test with measurement of ventilatory efficiency (end-tidal carbon dioxide pressure) with a handheld monitor. In a prospective, multi-center design the investigators will include patients evaluated for suspected lung cancer. The main objective is to establish threshold values for end-tidal carbon dioxide associated with low respectively high risk of major complications in patients undergoing surgery. In addition, the study aims to determine if end-tidal carbon dioxide can predict severe side-effects during neoadjuvant or curatively aiming systemic therapy. The project is closely linked to clinical practice, and the results can be easily implemented due to the simple and cost-efficient methodology. the suggested simplified approach would also allow access to physiological evaluation where more advanced methods are unavailable.",[135,136,137,138,139,140],"Lung Cancer (Diagnosis)","Lobectomy","Surgery Complications","Neoadjuvant Chemoimmunotherapy","End-Tidal Carbon Dioxide","Exercise","NOT_YET_RECRUITING","2026-04-02",{"date":144,"type":145},"2026-04-08","ACTUAL",{"date":147,"type":130},"2026-04-01",{"date":149,"type":130},"2029-12",{"name":5,"class":6},5]