[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640321":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":17,"centralContacts":31,"locations":37,"responsibleParty":53,"collaborators":17,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":17,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":17,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":17,"overallStatus":40,"whyStopped":17,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"First Affiliated Hospital of Wenzhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Single-Port Group","EXPERIMENTAL","Participants in this group will undergo radical proximal gastrectomy utilizing the SP1000 single-port surgical platform. The procedure focuses on performing the main surgical maneuvers through a centralized access point to evaluate the safety and clinical performance of the robotic system.",[13],"Device: Single-Port Robotic Surgical System",{"label":15,"type":16,"description":17,"interventionNames":18},"Traditional Laparoscopy Group","ACTIVE_COMPARATOR",null,[19],"Procedure: Traditional Laparoscopic Surgery",[21,26],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":17},"DEVICE","Single-Port Robotic Surgical System","An investigational robotic-assisted surgical platform designed for single-port access. In this study, the system is utilized to perform radical proximal gastrectomy. The core surgical procedures are conducted through a centralized access point to assess the intraoperative safety and short-term clinical outcomes of this robotic-assisted approach.",[9],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":17},"PROCEDURE","Traditional Laparoscopic Surgery","Standard multi-port laparoscopic radical proximal gastrectomy performed as a clinical control. This procedure follows conventional laparoscopic techniques involving multiple abdominal incisions for the placement of surgical instruments and camera to treat proximal gastric cancer.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":17,"email":36},"Xian Shen","CONTACT","+86 139 6888 8872","shenxian1120@126.com",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":17,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"The First Affiliated Hospital of Wenzhou Medical University","RECRUITING","Wenzhou","Zhejiang","China","CN",{"type":46,"coordinates":47},"Point",[48,49],120.66682,27.99942,{"lat":49,"lon":48},[52],{"name":33,"role":34,"phone":35,"phoneExt":17,"email":36},{"type":54,"investigatorFullName":17,"investigatorTitle":17,"investigatorAffiliation":17,"oldNameTitle":17,"oldOrganization":17},"SPONSOR","100640321","single-port-versus-conventional-laparoscopic-surgery-for-radical-proximal-gastric-cancer-a-randomized-controlled-trial-100640321",false,"NCT07586384","Single-port Versus Conventional Laparoscopic Surgery for Radical Proximal Gastric Cancer: A Randomized Controlled Trial","A Prospective, Single-center, Randomized Control Led Study of Laparoscopic Single-port Surgery System Versus Traditional Laparoscopic Surgery in Radical Proximal Gastric Cancer","Inclusion Criteria:\n\n* Age between 18 and 75 years inclusive.\n\nECOG performance status ≤ 2.\n\nHistologically confirmed proximal gastric cancer or Siewert type II adenocarcinoma of the esophagogastric junction.\n\nClinical stage cT1-T3, N0-N+, M0.\n\nTumor maximum diameter ≤ 4 cm and esophageal invasion ≤ 2 cm.\n\nCandidates for radical proximal gastrectomy (PG) with feasibility of R0 resection and functional anastomosis.\n\nAssessed by a Multidisciplinary Team (MDT) as suitable for PG rather than total gastrectomy, with no requirement for neoadjuvant therapy.\n\nRadiographic evidence of localized disease (no distant metastasis to liver, lung, or peritoneum via enhanced CT or MRI).\n\nASA physical status classification ≤ III.\n\nAdequate bone marrow, hepatic, renal, cardiac, and pulmonary function.\n\nAbility to understand and provide written informed consent.\n\nWillingness and ability to comply with the 12-month postoperative follow-up schedule.\n\nExclusion Criteria:\n\n* Clinical stage T4 or presence of distant metastasis.\n\nEsophageal invasion exceeding 2 cm.\n\nHistory of previous major gastric surgery (e.g., partial or total gastrectomy).\n\nOther malignant tumors within the last 5 years.\n\nSevere organic diseases that preclude safe anesthesia or surgery (e.g., severe heart failure, pulmonary fibrosis).\n\nRequirement for emergency surgery due to active gastric bleeding, perforation, or acute obstruction.\n\nPregnant or lactating women.\n\nSerious psychiatric disorders or cognitive impairment that interferes with study compliance.\n\nAny other condition that, in the opinion of the investigator, would make the participant unsuitable for the study.","ALL","18 Years","80 Years",{"count":66,"type":67},90,"ESTIMATED","INTERVENTIONAL",[70],"NA","To evaluate the safety and efficacy of SP1000 and conventional laparoscopy in radical gastrectomy for proximal gastric cancer.",[73,74],"Stomach Neoplasms","Robotic Surgical Procedures","2026-05-08",{"date":77,"type":78},"2026-05-14","ACTUAL",{"date":80,"type":78},"2025-11-05",{"date":82,"type":67},"2027-09-30",{"name":5,"class":6},1]