[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558277":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":43,"responsibleParty":62,"collaborators":24,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":24,"enrollmentInfo":74,"targetDuration":24,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":88,"overallStatus":46,"whyStopped":24,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Vastra Gotaland Region","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Single-session panretinal PRP (SS-PRP)","ACTIVE_COMPARATOR","Administration of all panretinal photocoagulation (PRP) treatment in one comprehensive session, typically delivered in a single clinical visit.",[13],"Procedure: Single-session panretinal PRP (SS-PRP)",{"label":15,"type":10,"description":16,"interventionNames":17},"Multiple-session panretinal PRP (MS-PRP)","Administration of panretinal photocoagulation (PRP) treatment over two separate visits with at least one week apart.",[18],"Procedure: Multiple-session panretinal PRP (MS-PRP)",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Administration of panretinal photocoagulation (PRP) treatment with navigated laser using Navilas in one comprehensive session, typically delivered in a single clinical visit.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Administration of panretinal photocoagulation (PRP) treatment with navigated laser using Navilas over two separate visits with at least one week apart.",[15],[29],{"name":30,"affiliation":31,"role":32},"Marita Andersson Grönlund, M.D. Prof","Göteborg University","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"Imadeddin Abu Ishkheidem, M.D.","CONTACT","+46738744867","imadeddin.abu.ishkheidem@vgregion.se",{"name":40,"role":36,"phone":41,"phoneExt":24,"email":42},"Sofia Töyrä Silfverswärd, PhD","+46761283085","sofia.toyra.silfversward@vgregion.se",[44],{"facility":45,"status":46,"city":47,"state":24,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Ögonmottagning Mölndal\u002FSU","RECRUITING","Mölndal","43130","Sweden","SE",{"type":52,"coordinates":53},"Point",[54,55],12.01378,57.6554,{"lat":55,"lon":54},[58,59],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},{"name":60,"role":36,"phone":61,"phoneExt":24,"email":42},"Sofia Töyrä Silfverswärd, PhD, MSc","+46705527103",{"type":63,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100558277","single-session-vs-multiple-session-panretinal-photocoagulation-for-treatment-of-proliferative-diabetic-retinopathy-100558277",false,"NCT06549023","Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy","Single Session vs Multiple-Session Panretinal Photocoagulation With Navigated Laser in Proliferative Diabetic Retinopathy - The SMART-PRP Study","SMART-PRP","Inclusion Criteria:\n\n* Age \\> 18 years.\n* Patients with type 1 or type 2 Diabetes Mellitus with newly diagnosed Proliferative Diabetic Retinopathy, PDR.\n* Visual acuity ≥ 0.1 Snellen.\n* CRT of less than 300 micrometer measured by OCT without cysts in the neuroretina.\n* Clear media and adequately dilated pupil for PRP.\n\nExclusion Criteria:\n\n* Intraocular surgery within the last 4 months or planned within the next 3 months.\n* Previous or current center-involved diabetic macular edema (Ci-DME).\n* Previous PRP, intravitreal treatment (IVT), or macular laser treatment in study eye.\n* Treatment with medications known to risk macular edema.\n* Media opacity preventing adequate PRP.\n* General medical condition making office laser treatment very difficult or impossible.","ALL","18 Years",{"count":75,"type":76},40,"ESTIMATED","INTERVENTIONAL",[79],"NA","Proliferative diabetic retinopathy (PDR) is the leading cause for blindness in working-age adults. The current gold standard treatment for PDR is panretinal photocoagulation (PRP). In current clinical practice, both single-session and multiple-session PRP approaches are widely accepted and utilized. The purpose of this study is to compare the safety and effectiveness of single-session and multiple-session PRP.",[82,83,84,85,86,87],"Proliferative Diabetic Retinopathy","Diabetic Retinopathy","Diabetic Retinopathy Visually Threatening","Diabetic Macular Edema","Diabetes Mellitus, Type 1","Diabetes Mellitus, Type 2",[89,90,91,92,93,94,95,96,97,98,99,100,101],"Panretinal photocoagulation (PRP)","Single-session PRP","Multiple-session PRP","Navigated laser","Navilas","Central subfield retinal thickness (CRT)","Macular volume","Optical coherence tomography (OCT)","Swept-source optical coherence tomography (SS-OCT)","Wide-field fundus imaging","OCT-angiography","Retinal oximetry","Electroretinogram (ERG)","2025-11-17",{"date":104,"type":105},"2025-11-18","ACTUAL",{"date":107,"type":105},"2025-01-01",{"date":109,"type":76},"2030-12-31",{"name":5,"class":6},1]