[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566648":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":25,"responsibleParty":89,"collaborators":10,"id":92,"slug":93,"hasResults":94,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":98,"eligibilityCriteria":99,"healthyVolunteers":94,"sex":100,"minAge":101,"maxAge":10,"enrollmentInfo":102,"targetDuration":10,"studyType":105,"phases":10,"briefSummary":106,"conditions":107,"keywords":109,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"IRCCS San Raffaele","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"BAV patients underoging TAVR",null,"Patients with bicuspid aortic valve undergoing TAVI for severe aortic stenosis with sizing performed",[13],{"name":14,"affiliation":15,"role":16},"Prof. Matteo Montorfano, MD","IRCCS San Raffaele Scientific Institute","PRINCIPAL_INVESTIGATOR",[18,22],{"name":14,"role":19,"phone":20,"phoneExt":10,"email":21},"CONTACT","0039\u002F02\u002F26437331","montorfano.matteo@hsr.it",{"name":23,"role":19,"phone":20,"phoneExt":10,"email":24},"Barbara Bellini, MD","bellini.barbara@hsr.it",[26,43,51,63,75],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":30,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Fondazione Poliambulanza","RECRUITING","Brescia","Italy","25100","IT",{"type":34,"coordinates":35},"Point",[36,37],10.21472,45.53558,{"lat":37,"lon":36},[40],{"name":41,"role":42,"phone":10,"phoneExt":10,"email":10},"Andrea Buono, MD","SUB_INVESTIGATOR",{"facility":44,"status":28,"city":29,"state":30,"zip":31,"country":30,"countryCode":32,"cosmosGeoPoint":45,"geoPoint":47,"contacts":48},"Spedali Civili",{"type":34,"coordinates":46},[36,37],{"lat":37,"lon":36},[49],{"name":50,"role":42,"phone":10,"phoneExt":10,"email":10},"Mauro Massussi, MD",{"facility":52,"status":28,"city":53,"state":30,"zip":54,"country":30,"countryCode":32,"cosmosGeoPoint":55,"geoPoint":59,"contacts":60},"Ospedale San Donato","Milan","20100",{"type":34,"coordinates":56},[57,58],9.18951,45.46427,{"lat":58,"lon":57},[61],{"name":62,"role":42,"phone":10,"phoneExt":10,"email":10},"Riccardo Gorla, MD",{"facility":64,"status":28,"city":65,"state":30,"zip":66,"country":30,"countryCode":32,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"San Camillo Hospital","Roma","00100",{"type":34,"coordinates":68},[69,70],11.10642,44.99364,{"lat":70,"lon":69},[73],{"name":74,"role":42,"phone":10,"phoneExt":10,"email":10},"Francesco DE Felice MD",{"facility":76,"status":28,"city":77,"state":78,"zip":79,"country":78,"countryCode":80,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Luzerner Kantonsspital","Lucerne","Switzerland","6009","CH",{"type":34,"coordinates":82},[83,84],8.30635,47.05048,{"lat":84,"lon":83},[87],{"name":88,"role":42,"phone":10,"phoneExt":10,"email":10},"Stefan Toggweiler, MD",{"type":16,"investigatorFullName":90,"investigatorTitle":91,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Matteo Montorfano","Professor, cardiologist","100566648","size-up-bicuspid-with-the-lira-method-the-sublime-study-100566648",false,"NCT06657911","Size Up Bicuspid With the LIra MEthod: the SUBLIME Study","SUBLIME: Size Up Bicuspid With the LIra MEthod: the SUBLIME Study","SUBLIME","Inclusion Criteria:\n\n* All patients over 18 years old with severe aortic stenosis and type 1 or 2 BAV according to Sievers classification) undergone TAVR with self-expanding supra-annular prostheses sized according to the LIRA method between September 2018 and June 2024\n\nExclusion Criteria:\n\n* Redo-TAVR\n* TAVR performed in emergency setting\n* TAVR performed for severe aortic regurgitation","ALL","18 Years",{"count":103,"type":104},250,"ESTIMATED","OBSERVATIONAL","Transcatheter aortic valve replacement (TAVR) outcomes in patients with raphe-type bicuspid aortic valve (BAV) are still suboptimal for the non negligible rate of stroke and permanent pacemaker implantation. There is still lack of consensus on the optimal sizing method for prosthesis selection in BAV patients.\n\nThe objective of the present study is to evaluate the efficacy and safety of the LIRA sizing method in raphe-type BAV patients undergoing TAVR.",[108],"Bicuspid Aortic Valve (BAV)",[110,111,112],"LIRA method","Bicuspid aortic Valve","TAVR","2025-01-02",{"date":115,"type":116},"2025-01-03","ACTUAL",{"date":118,"type":116},"2024-12-21",{"date":120,"type":104},"2026-04-30",{"name":5,"class":6},5]