[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100053922":3},{"organization":4,"outcomesModule":7,"designInfo":20,"detailedDescription":19,"studyPopulation":23,"armGroups":24,"interventions":19,"overallOfficials":19,"centralContacts":31,"locations":37,"responsibleParty":53,"collaborators":19,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":19,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":19,"studyType":69,"phases":19,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":40,"whyStopped":19,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Split, School of Medicine","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":19,"otherOutcomes":19},[9,13,16],{"measure":10,"description":11,"timeFrame":12},"Change in Transepidermal Water Loss (TEWL)","Skin barrier function will be assessed by measuring transepidermal water loss using a Tewameter TM 300 probe. Values will be expressed in g\u002Fm²\u002Fh","Single assessment during the study visit",{"measure":14,"description":15,"timeFrame":12},"Change in Skin Hydration","Hydration of the stratum corneum will be assessed using a Corneometer CM 825 probe.",{"measure":17,"description":18,"timeFrame":12},"Change in Skin Erythema","Skin erythema will be assessed using a Mexameter MX 18 probe.",null,{"allocation":19,"interventionModel":19,"interventionModelDescription":19,"primaryPurpose":19,"observationalModel":21,"timePerspective":22,"maskingInfo":19},"CASE_CONTROL","CROSS_SECTIONAL","Healthy adult women recruited from the general population. Participants will be classified into two groups based on their self-reported use of UV nail lamps during nail treatments: regular users of UV nail lamps and women who do not regularly use UV nail lamps and have natural nails.",[25,28],{"label":26,"type":19,"description":27,"interventionNames":19},"Regular UV Nail Lamp Users","Healthy adult women who regularly undergo nail treatments involving exposure to UV lamps.",{"label":29,"type":19,"description":30,"interventionNames":19},"Non-Users of UV Nail Lamps","Healthy adult women who do not regularly undergo nail treatments involving exposure to UV lamps and have natural nails.",[32],{"name":33,"role":34,"phone":35,"phoneExt":19,"email":36},"Josipa Bukić","CONTACT","+385917933753","jbukic@mefst.hr",[38],{"facility":39,"status":40,"city":41,"state":19,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"University of Split School of Medicine","RECRUITING","Split","2100","Croatia","HR",{"type":46,"coordinates":47},"Point",[48,49],16.43915,43.50891,{"lat":49,"lon":48},[52],{"name":33,"role":34,"phone":35,"phoneExt":19,"email":36},{"type":54,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100053922","skin-barrier-function-in-women-using-uv-nail-lamps-100053922",false,"NCT07700186","Skin Barrier Function in Women Using UV Nail Lamps","Comparison of Objective Skin Barrier Function Parameters Between Women Who Use and Women Who Do Not Use UV Nail Lamps for Nail Treatments","Inclusion Criteria:\n\n* Healthy adult women (≥18 years of age)\n* Willing and able to provide written informed consent\n* Willing to complete the study questionnaire\n\nExclusion Criteria:\n\n* Active skin diseases (e.g., psoriasis, vitiligo, or other dermatological conditions)\n* Allergic contact dermatitis\n* Pregnancy or breastfeeding\n* Use of topical or systemic corticosteroids, immunosuppressive drugs, or antihistamines",true,"FEMALE","18 Years","50 Years",{"count":67,"type":68},30,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to compare objective parameters of skin barrier function between healthy adult women who regularly use UV lamps during nail treatments and women who do not use UV lamps.\n\nThe main questions it aims to answer are:\n\n* Do women who regularly use UV lamps for nail treatments show differences in skin barrier function compared to women who do not use UV lamps?\n* Are transepidermal water loss, skin hydration, and erythema associated with regular exposure to UV lamps used for nail treatments?\n* Does the duration of UV lamp use influence skin barrier function parameters?\n\nResearchers will compare women who regularly use UV lamps during nail treatments with women who have natural nails and do not regularly expose their hands to UV lamps.\n\nParticipants will:\n\n* Attend a single study visit.\n* Complete a short questionnaire regarding nail care habits and duration of UV lamp use.\n* Undergo non-invasive measurements of skin barrier function on the hands, including transepidermal water loss, skin hydration, and erythema assessments.",[72],"Effects of UV Nail Lamps on Skin Barrier Function",[74,75,76,77,78,79],"UV nail lamps","Gel manicure","Skin barrier function","Transepidermal water loss (TEWL)","Skin hydration","Erythema","2026-07-07",{"date":82,"type":83},"2026-07-13","ACTUAL",{"date":85,"type":68},"2026-07",{"date":87,"type":68},"2027-07",{"name":5,"class":6},1]