[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556795":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":39,"responsibleParty":60,"collaborators":24,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":24,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":24,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":24,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Texas Southwestern Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Hot and Dry Environment_no cooling","EXPERIMENTAL","Subjects will exercise for 60 minutes in a hot and dry environment while being exposed to no cooling.",[13],"Other: Non-cooling",{"label":15,"type":10,"description":16,"interventionNames":17},"Hot and Dry Environment_whole body skin wetting","Subjects will exercise for 60 minutes in a hot and dry environment while being exposed to whole body skin wetting.",[18],"Other: Whole body cooling",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Whole body cooling","Subjects will exercise for 60 minutes in the indicated environmental condition while being exposed to whole body skin wetting. Skin wetting will be performed by spraying water onto the whole body throughout the exercise bout.",[15],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Non-cooling","Subjects will exercise for 60 minutes in the indicated environmental condition while being exposed to no cooling modalities.",[9],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Craig Crandall, PhD","CONTACT","214-345-4623","craigcrandall@texashealth.org",{"name":36,"role":32,"phone":37,"phoneExt":24,"email":38},"Erin Harper, BS","214-345-4737","ErinHarper@texashealth.org",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Institute for Exercise and Environmental Medicine","RECRUITING","Dallas","Texas","75231","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-96.80667,32.78306,{"lat":52,"lon":51},[55,56],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},{"name":57,"role":32,"phone":58,"phoneExt":24,"email":59},"Taysom Wallace, MS","214-345-5022","taysomwallace@texashealth.org",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Craig Crandall","Professor","100556795","skin-wetting-in-burn-survivors-100556795",false,"NCT06529757","Skin Wetting in Burn Survivors","Inclusion Criteria: Non-burn survivors\n\n* Healthy male and female subjects\n* 18-65 years of age.\n* Free of any underlying medical conditions\n\nExclusion Criteria (non-burned individuals):\n\n* Any burn-related injuries resulting in at least one night of hospitalization.\n* Heart disease or any other chronic medical condition requiring regular medical therapy including cancer, diabetes, and hypertension.\n* Abnormalities detected on routine screening\n* Individuals who participate in a structured aerobic exercise training program at moderate to high intensities.\n* Current smokers, as well as individuals who regularly smoked within the past 3 years.\n* Body mass index of greater than 30 kg\u002Fm\\^2.\n* Pregnant individuals\n\nInclusion Criteria (burn survivors):\n\n* Healthy male and female subjects\n* 18-65 years of age.\n* Free of any underlying medical conditions\n* Having a burn injury covering 20-40% or \\>40% of the participant's body surface area; at least 50% of those burn injuries must be full thickness that required skin grafting.\n* Participants must have been hospitalized due to the burn injury for a minimum of 15 days\n\nExclusion Criteria (burn survivors):\n\n* Any burn-related injuries resulting in at least one night of hospitalization.\n* Heart disease or any other chronic medical condition requiring regular medical therapy including cancer, diabetes, and hypertension.\n* Abnormalities detected on routine screening\n* Individuals who participate in a structured aerobic exercise training program at moderate to high intensities.\n* Current smokers, as well as individuals who regularly smoked within the past 3 years.\n* Body mass index of greater than 30 kg\u002Fm\\^2.\n* Pregnant individuals\n* Extensive unhealed injured skin",true,"ALL","18 Years","65 Years",{"count":75,"type":76},40,"ESTIMATED","INTERVENTIONAL",[79],"NA","This project will identify the efficacy of whole body skin wetting aimed to attenuate excessive elevations in internal body temperatures during physical activity in well-healed burn survivors. The investigators will conduct a randomized crossover design study. Non-burned control subjects, subjects who experienced burns covering \\~20% to 40% of their body surface area, and subject having burns \\>40% of their body surface area will be investigated. Subjects will exercise in heated environmental conditions while receiving no cooling or whole body skin wetting.",[82],"Burn Injury","2025-10-20",{"date":85,"type":86},"2025-10-21","ACTUAL",{"date":88,"type":86},"2024-07-31",{"date":90,"type":76},"2026-07-31",{"name":5,"class":6},1]