[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619545":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":37,"centralContacts":43,"locations":52,"responsibleParty":73,"collaborators":76,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":29,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":102,"overallStatus":106,"whyStopped":29,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"University of Pittsburgh","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Sleep Feedback + Psychoeducation","EXPERIMENTAL","Participants receive an actigraphy watch to track their sleep and activity levels and complete a daily sleep diary; sleep feedback graphs show participants their actigraphy watch and sleep diary data on demand.",[13],"Behavioral: Sleep Feedback + Psychoeducation",{"label":15,"type":10,"description":16,"interventionNames":17},"Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+)","Participants will attend 6-8 TSC sessions of a manualized sleep intervention with a Sleep therapist, delivered in person or videoconference. Participants will also wear bright light glasses (up to 60 minutes) in the morning and blue light blocking glasses in the evening throughout the intervention.\n\nAdditionally, participants receive an actigraphy watch to track their sleep and activity levels and complete a daily sleep diary; sleep feedback graphs show participants their actigraphy watch and sleep diary data on demand.",[13,18],"Behavioral: Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+)",{"label":20,"type":10,"description":21,"interventionNames":22},"Triple Chronotherapy + Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+)","TCT+ Participants receive a four-day intervention, beginning with an approximately 33-hour total sleep deprivation period, followed by 3-days of sleep phase advancement and daily bright light therapy (up to sixty minutes) in the morning and blue light blocking glasses (up to one hour before bedtime) in the evening, in a sleep lab.\n\nTSC+ Participants will also attend 6-8 TSC sessions of a manualized sleep intervention with a Sleep therapist, delivered in person or videoconference. Participants will continue to wear bright light glasses (up to sixty minutes daily) in the morning and blue light blocking glasses (up to one hour before bedtime) in the evening throughout the intervention.\n\nSF Participants receive an actigraphy watch to track their sleep and activity levels and complete a daily sleep diary; sleep feedback graphs show participants their actigraphy watch and sleep diary data on demand.",[13,18,23],"Behavioral: Triple Chronotherapy (TCT+)",[25,30,33],{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"BEHAVIORAL","Participants are provided with an actigraphy watch that is used to monitor their sleep and activity throughout the day and complete a sleep diary daily. Along with wearing the watch they also will be provided access to their actigraphy and sleep diary graphs that document their data on demand via smartphone link.",[9,15,20],null,{"type":26,"name":15,"description":31,"armGroupLabels":32,"otherNames":29},"Behavioral: TSC+\n\n• This intervention includes participants attending 6-8 sessions of a manualized sleep intervention with a Sleep Therapist, delivered in person or videoconference, as well as daily bright light therapy (up to one hour daily) and blue light blocking glasses (up to one hour before bedtime)",[15,20],{"type":26,"name":34,"description":35,"armGroupLabels":36,"otherNames":29},"Triple Chronotherapy (TCT+)","Behavioral: TCT+\n\n• One night of total sleep deprivation followed by three nights of sleep phase advancement in the sleep lab, daily bright light therapy (up to one hour daily) and blue light blocking glasses (up to one hour before bedtime), in a sleep lab.",[20],[38,41],{"name":39,"affiliation":5,"role":40},"Tina Goldstein, PhD","PRINCIPAL_INVESTIGATOR",{"name":42,"affiliation":5,"role":40},"Peter Franzen",[44,49],{"name":45,"role":46,"phone":47,"phoneExt":29,"email":48},"Dawn Rice, MS","CONTACT","412-297-1947","ricedm@upmc.edu",{"name":39,"role":46,"phone":50,"phoneExt":29,"email":51},"412-246-5604","goldtr@upmc.edu",[53],{"facility":54,"status":29,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"Western Psychiatric Hospital\u002FUniversity of Pittsburgh","Pittsburgh","Pennsylvania","15213","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-79.99589,40.44062,{"lat":64,"lon":63},[67,68,70,71],{"name":45,"role":46,"phone":47,"phoneExt":29,"email":48},{"name":69,"role":46,"phone":29,"phoneExt":29,"email":51},"Tina Goldstein, MS",{"name":39,"role":40,"phone":29,"phoneExt":29,"email":29},{"name":72,"role":40,"phone":29,"phoneExt":29,"email":29},"Peter Franzen, PhD",{"type":40,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Tina R Goldstein","Professor",[77],{"name":78,"class":6},"American Foundation for Suicide Prevention","100619545","sleep-and-circadian-interventions-for-college-students-at-high-risk-of-suicide-100619545",false,"NCT07346014","Sleep and Circadian Interventions for College Students at High Risk of Suicide","Triple Chronotherapy + Transdiagnostic Sleep and Circadian Intervention (TSC+) for Suicidal Young Adults","REST-UP","Inclusion Criteria:\n\n* Enrolled or planning to enroll in treatment at COSTAR Intensive Outpatient Program\n* English language fluency and literacy sufficient to engage in study protocol\n* Suicidal ideation or suicide attempt in past month\n* Clinically significant sleep disturbance, operationalized as Pittsburgh Sleep Quality Index global PSQI score \\>= 7, and\u002For delayed bedtimes (\\>midnight), and\u002For \\>2 hours in sleep timing variability\n\nExclusion Criteria:\n\n* Non-affective psychosis per electronic health record (EHR) review and\u002For baseline clinical assessment, or symptom severity or psychosocial functioning impairments that preclude participation\n* Contraindications for either sleep deprivation or bright light therapy (e.g., bipolar disorder; seizure disorder; photosensitizing medication)\n* Intellectual disability precluding comprehension of study procedures\n* Evidence of untreated obstructive sleep apnea and\u002For restless legs syndrome\n* Life-threatening medical condition requiring immediate treatment (such as cancer; end stage disease)\n* Pregnancy","ALL","18 Years","25 Years",{"count":91,"type":92},90,"ESTIMATED","INTERVENTIONAL",[95],"NA","The purpose of this study is to examine the extent to which delivering sleep and circadian focused interventions in addition to evidenced based psychiatric care for depression and suicide risk may contribute to decreasing suicide risk among high risk young adults. Investigators will evaluate three interventions targeting sleep in acutely suicidal college students enrolled in intensive outpatient treatment. Participants will be randomly assigned to one of three intervention groups:\n\n1. Triple Chronotherapy (TCT)+ Transdiagnostic Sleep and Circadian Intervention (TSC)\n2. Transdiagnostic Sleep and Circadian Intervention (TSC)\n3. Sleep Feedback (SF) Participants will be followed for 6 months with primary outcome domains of suicidal thoughts and behaviors and depression evaluated by blinded clinicians at short (Days 1-4 of intervention), medium (2 months) and long (6 month) term intervals.",[98,99,100,101],"Sleep Disturbance","Sleep","Depression","Suicide",[103,104,105],"sleep disturbance","suicide","triple chronotherapy","NOT_YET_RECRUITING","2026-04-14",{"date":109,"type":110},"2026-04-16","ACTUAL",{"date":112,"type":92},"2026-06",{"date":114,"type":92},"2029-03",{"name":5,"class":6},1]