[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560744":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":18,"responsibleParty":37,"collaborators":18,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":18,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":18,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":60,"whyStopped":18,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":18},{"fullName":5,"class":6},"Duke University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Alarm","EXPERIMENTAL","Patients in the alarm group will have an alarm system placed in their room, scheduled to sound at 4 timepoints during the night (specific timepoints adjusted based on patient's preferred bed times). This intervention will stop when the clinical team has collected sufficient seizures for clinical decision making.",[13],"Device: Alarm system",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Patients in the control group will have an alarm system placed in their room, but the alarm system will not sound during any of the nights during their EMU admission.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DEVICE","Alarm system","Generic alarm system programmed to sound during the night to try to induce arousals from sleep.",[9],[26],{"name":27,"affiliation":5,"role":28},"Birgit Frauscher, MD PD","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","9196139386","birgit.frauscher@duke.edu",{"name":35,"role":31,"phone":18,"phoneExt":18,"email":36},"Mays Khweileh, MD","mays.khweileh@duke.edu",{"type":38,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100560744","sleep-disruption-pattern---epilepsy-monitoring-unit-100560744",false,"NCT06581133","Sleep Disruption Pattern - Epilepsy Monitoring Unit","Introducing a Structured Sleep Disruption Pattern to Provoke Earlier Seizures During Epilepsy Monitoring Unit Admissions","Inclusion Criteria:\n\n* Age 14 to 60 years\n* EMU monitoring for presurgical evaluations\n* Average 2-3 seizures per week based on pre-admission seizure diary\n* Sleep as a known seizure trigger\n\nExclusion Criteria:\n\n\\- Multiple seizures a day based on pre-admission seizure diary","ALL","14 Years","60 Years",{"count":50,"type":51},75,"ESTIMATED","INTERVENTIONAL",[54],"NA","Epilepsy affects millions worldwide, with 40% of patients experiencing uncontrolled seizures despite medication. Comprehensive epilepsy centers recommend continuous video-electroencephalography monitoring to define seizure type and distinguish mimickers. This process, however, is resource-intensive, with lengthy hospital stays. The investigators' recent study identified a heightened association between arousals and epileptic activity in drug-resistant focal epilepsy patients. Building on these findings, the investigators aim to explore whether disrupting sleep with an alarm system triggers earlier occurrence of seizures, potentially offering insights to reduce hospital stay durations in epilepsy monitoring units.",[57],"Epilepsy Intractable",[59],"epilepsy monitoring unit","NOT_YET_RECRUITING","2026-02-09",{"date":63,"type":64},"2026-02-11","ACTUAL",{"date":66,"type":51},"2026-06-01",{"date":68,"type":51},"2027-12-01",{"name":5,"class":6}]