[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642528":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":135,"collaborators":138,"id":147,"slug":148,"hasResults":149,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":10,"eligibilityCriteria":153,"healthyVolunteers":149,"sex":154,"minAge":155,"maxAge":156,"enrollmentInfo":157,"targetDuration":10,"studyType":160,"phases":10,"briefSummary":161,"conditions":162,"keywords":164,"overallStatus":91,"whyStopped":10,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":180},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Pediatric patients 5-16 years of age",null,"Pediatric patients admitted to a study site with suspected or proven infection",[13],"Other: No Intervention: Observational Cohort",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"No Intervention: Observational Cohort","This is a non-interventional study",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Matthew Wiens, PhD","CONTACT","604-829-2562","matthew.wiens@bcchr.ca",[26,48,63,76,89,106,124],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"University of California, San Francisco","NOT_YET_RECRUITING","San Francisco","California","94117","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-122.41942,37.77493,{"lat":38,"lon":37},[41,44,46],{"name":42,"role":43,"phone":10,"phoneExt":10,"email":10},"Anneka Hooft, MD, MPH","SUB_INVESTIGATOR",{"name":45,"role":43,"phone":10,"phoneExt":10,"email":10},"Teresa Kortz, MD, MS, PhD",{"name":47,"role":43,"phone":10,"phoneExt":10,"email":10},"Charles Langelier, MD, PhD",{"facility":49,"status":28,"city":50,"state":51,"zip":52,"country":32,"countryCode":33,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"Weill Cornell Medicine","Ithaca","New York","14850",{"type":35,"coordinates":54},[55,56],-76.49661,42.44063,{"lat":56,"lon":55},[59,61],{"name":60,"role":43,"phone":10,"phoneExt":10,"email":10},"Duncan Hau, MD",{"name":62,"role":43,"phone":10,"phoneExt":10,"email":10},"Radhika Lu Sundararajan, MD, MA, PhD",{"facility":64,"status":28,"city":65,"state":66,"zip":67,"country":32,"countryCode":33,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"University of Washington","Seattle","Washington","98195",{"type":35,"coordinates":69},[70,71],-122.33207,47.60621,{"lat":71,"lon":70},[74],{"name":75,"role":43,"phone":10,"phoneExt":10,"email":10},"Jerry Zimmerman, MD, PhD",{"facility":77,"status":78,"city":79,"state":80,"zip":81,"country":82,"countryCode":83,"cosmosGeoPoint":84,"geoPoint":88,"contacts":10},"BC Children's Hospital Research 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Sciences","Mwanza","Tanzania",{"type":35,"coordinates":111},[112,113],32.9,-2.51667,{"lat":113,"lon":112},[116,118,120,122],{"name":117,"role":103,"phone":10,"phoneExt":10,"email":10},"Neema Kayange, MD",{"name":119,"role":43,"phone":10,"phoneExt":10,"email":10},"Rob Peck",{"name":121,"role":43,"phone":10,"phoneExt":10,"email":10},"Bahati Msaki",{"name":123,"role":43,"phone":10,"phoneExt":10,"email":10},"Stephen Mshana, MD, MMed, PhD",{"facility":125,"status":126,"city":127,"state":10,"zip":10,"country":128,"countryCode":129,"cosmosGeoPoint":130,"geoPoint":134,"contacts":10},"WALIMU","COMPLETED","Mbarara","Uganda","UG",{"type":35,"coordinates":131},[132,133],30.64851,-0.60467,{"lat":133,"lon":132},{"type":103,"investigatorFullName":136,"investigatorTitle":137,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Matthew Wiens","Assistant Professor",[139,140,143,145],{"name":27,"class":6},{"name":141,"class":142},"World Alliance for Lung and Intensive Care Medicine in Uganda","UNKNOWN",{"name":144,"class":6},"Catholic University of Health and Allied Sciences",{"name":146,"class":142},"Centre Hospitalier Universitaire de Kigali","100642528","smart-discharges-for-older-children-100642528",false,"NCT07629154","Smart Discharges for Older Children","Smart Discharges for Older Children: A Cohort Study to Develop Prognostic Algorithms for Post-discharge Readmission and Mortality Among Children Over 5 Years of Age","Inclusion Criteria:\n\n* Age between 0 and 16 years admitted to pediatric ward of hospital for proven or suspected infection\n* Provide informed consent\n* Ability to provide contact information (phone number or address) for phone or in-person follow-up\n\nExclusion Criteria:\n\n* Child lives outside of the catchment area of a study site\n* Admitted for elective procedures, trauma, or short-term observation\n* Language barriers","ALL","5 Years","16 Years",{"count":158,"type":159},4000,"ESTIMATED","OBSERVATIONAL","This study is an observational multi-country cohort study that aims to build algorithms that can identify children between 5 and 16 years of age admitted for proven or suspected sepsis who are at risk of mortality after they are discharged in East Africa.\n\nIn low- and middle-income countries, about 5% of children discharged after hospitalization for sepsis will die in the weeks after returning home. Doctors and parents are often unaware of this period of vulnerability and are poorly equipped to identify or handle this critical situation. This project builds on past work that developed and evaluated models and the Smart Discharges program to predict, during hospitalization, an individual child's risk of recurrent illness and mortality, as well as to provide additional post-discharge support to at-risk children.\n\nParticipants will be enrolled from facilities once they are admitted, collecting clinical and social variables. They will then be followed until 6 months post-discharge to understand what happens to them after they return home. This data will be evaluated to identify which variables collected at facilities can be predictive of mortality and recurrent illness after discharge.",[163],"Sepsis",[165,166,167,168,169,170],"pediatrics","sepsis","risk-prediction","critical care","post-discharge","patient discharge","2026-06-10",{"date":173,"type":174},"2026-06-15","ACTUAL",{"date":176,"type":174},"2024-01-02",{"date":178,"type":159},"2027-04",{"name":5,"class":6},7]