[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549359":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":44,"centralContacts":49,"locations":58,"responsibleParty":77,"collaborators":79,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":90,"sex":91,"minAge":92,"maxAge":32,"enrollmentInfo":93,"targetDuration":32,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":103,"overallStatus":60,"whyStopped":32,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14,21],{"label":9,"type":10,"description":11,"interventionNames":12},"Focus Group","OTHER","The investigators will iteratively develop an acceptable mobile CM protocol using qualitative feedback from Veterans in VA patients in LCS or in cancer care and LCS and oncology staff.",[13],"Behavioral: Focus Group",{"label":15,"type":16,"description":17,"interventionNames":18},"Contingency Management","EXPERIMENTAL","Veterans in VA LCS or cancer care will receive mobile CM plus behavioral counseling and cessation medication over 5 weeks.",[19,20],"Behavioral: Contingency Management","Behavioral: Behavioral Counseling (Cognitive Behavioral Therapy, CBT)",{"label":22,"type":23,"description":24,"interventionNames":25},"TUD Treatment as Usual","ACTIVE_COMPARATOR","Participants assigned to TAU will receive time-matched Medication Management plus usual care (referral to VA Tobacco Cessation Clinic and provision of the VA Telequit quitline).",[20,26],"Behavioral: TUD Treatment as Usual (TAU)",[28,33,36,40],{"type":29,"name":9,"description":30,"armGroupLabels":31,"otherNames":32},"BEHAVIORAL","In 60-minute focus groups, participants will be categorized based on their survey responses and engaged in semi-structured discussions using open-ended questions and probes to gather detailed information. The moderators will follow best practices in qualitative research, introducing the topic of smoking cessation in the context of cancer screening and treatment and guiding the discussions from broader issues to participant-generated examples.",[9],null,{"type":29,"name":15,"description":34,"armGroupLabels":35,"otherNames":32},"Participants will provide baseline data on their recent substance use and smoking habits and severity. They will receive a CO monitor and iCO app and will upload videos verifying smoking abstinence a minimum of once per day, 5 times per week. Financial incentives will be provided at weekly visits contingent on tobacco abstinence verified through Remote (mobile) CO monitoring. They will receive clinician feedback at the time of each CO reading, following established VA protocols for CM.",[15],{"type":29,"name":37,"description":38,"armGroupLabels":39,"otherNames":32},"Behavioral Counseling (Cognitive Behavioral Therapy, CBT)","Participants will receive a 5-session smoking cessation behavioral counseling for approximately 15-20 minutes weekly. Sessions may be held by secure video conference or by telephone, per participant preference. Sessions will use CBT principles with MI incorporated for resolving reluctance to quit.",[15,22],{"type":29,"name":41,"description":42,"armGroupLabels":43,"otherNames":32},"TUD Treatment as Usual (TAU)","Participants assigned to TAU will receive referral to VA Tobacco Cessation Clinic and provision of the VA Telequit quitline. The VA Tobacco Cessation Clinic is modeled after VA Tobacco Cessation Clinics across all VA facilities and involves delivery of brief counseling and pharmacotherapy for TUD if desired. VA Telequit is a national toll-free number available to Veterans that allows them to speak with a smoking cessation counselor for a recommended minimum of five sessions to develop a quit plan and receive counseling, strategies to prevent relapse, and weekly proactive follow-up calls based on National Cancer Institute guidelines.",[22],[45],{"name":46,"affiliation":47,"role":48},"Ellen Herbst, MD","San Francisco VA Medical Center, San Francisco, CA","PRINCIPAL_INVESTIGATOR",[50,55],{"name":46,"role":51,"phone":52,"phoneExt":53,"email":54},"CONTACT","(415) 221-4810","24926","Ellen.Herbst@va.gov",{"name":56,"role":51,"phone":52,"phoneExt":53,"email":57},"Madeline Martinez Rivas, PhD","madeline.martinezrivas@va.gov",[59],{"facility":47,"status":60,"city":61,"state":62,"zip":63,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"RECRUITING","San Francisco","California","94121-1563","United States","US",{"type":67,"coordinates":68},"Point",[69,70],-122.41942,37.77493,{"lat":70,"lon":69},[73,75,76],{"name":46,"role":51,"phone":74,"phoneExt":53,"email":54},"415-221-4810",{"name":56,"role":51,"phone":52,"phoneExt":53,"email":57},{"name":46,"role":48,"phone":32,"phoneExt":32,"email":32},{"type":78,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[80],{"name":81,"class":10},"University of California, San Francisco","100549359","smoking-cessation-cm-for-veterans-with-or-at-risk-for-cancer-100549359",false,"NCT06432985","Smoking Cessation CM for Veterans With or at Risk for Cancer","Contingency Management for Veteran Smokers With or at Risk for Cancer","CM_TUD_Cancer","Inclusion Criteria:\n\nIn order to be eligible to participate in this study, an individual must meet all of the following criteria:\n\n* Human Subjects Involvement and Characteristics: This Proof of Concept and Clinical Trial has three stages. The Proof-of-Concept Phase (Years 1-2) includes a Focus Group phase (Year 1) in which the investigators will recruit both Veterans and non-Veterans (VA clinical staff); and a Pilot Study (Year 2) in which the investigators will recruit Veterans in LCS or cancer treatment at San Francisco VA Healthcare System (SFVAHCS). If the Pilot Study is successful, the investigators will recruit Veterans in LCS or cancer treatment for the RCT (Years 3-6).\n* Focus Groups: For Focus Groups (Year 1), the investigators will recruit both Veterans and VA clinical staff at SFVAHCS.\n\nVeterans:\n\n* Age 18 years or older\n* Veteran eligible for VA healthcare\n* English-speaking\n* Received SFVAHCS cancer monitoring or treatment or LCS within the past 24 months\n* Active cigarette smoking within the past 24 months\n* Have access to Wi-Fi and a device that supports audio and video communication\n\nVA Clinical Staff:\n\n* Current member of clinical staff at the SFVAHCS\n* Have participated in the care of at least 5 VA cancer or LCS patients in the past 6 months\n\nPilot Feasibility Study (Year 2) and Randomized Controlled Trial\n\nInclusion criteria:\n\n* Age 18 years or older\n* Veteran currently receiving medical care at SFVAHCS (at least one clinical visit same calendar year for cancer)\n* English-speaking\n* Current, active (same calendar year) enrollment in VA LCS, or current (same calendar year) diagnosis of cancer documented in the VA medical record, confirmed through medical record review\n* Current (past 30 days) cigarette smoking a minimum of 1 cigarette per day (average), assessed by Timeline Followback (TLFB)92, 99-101\n* Open to receiving smoking cessation interventions\n\nExclusion Criteria:\n\nFocus Groups: For Focus Groups (Year 1), the investigators will recruit both Veterans and VA clinical staff at SFVAHCS.\n\nVeterans:\n\nExclusion criteria: Assessed by Co-PIs' medical record review:\n\n* Current severe, untreated mental illness (i.e., psychosis, bipolar disorder, and\u002For substance use disorder (SUD)) and\u002For\n* Current (past 30 days) active suicidal\u002Fhomicidal ideation or severe behavioral instability that would prevent participation\n* Never smokers or quit smoking for longer than 36 months prior to consent (4) no access to Wi-Fi or devices that support audio and video communication\n\nVA Clinical Staff:\n\nExclusion Criteria:\n\n* Unable to commit 1.5 hours (60 min focus group and self-report questionnaires)\n\nPilot Feasibility Study (Year 2) and Randomized Controlled Trial\n\nExclusion Criteria:\n\n* An individual who meets any of the following criteria will be excluded from participation in this study:\n* Evaluated by investigative team medical record review and clinical assessment:\n* Psychotic disorders, bipolar disorder, neurocognitive disorder, substance use disorders, or other psychiatric or medical conditions judged by the PI to be unstable in the past 30 days, based on screening results and\u002For medical record review, including conditions for which large sums of money would be potentially destabilizing\n* Untreated, current, active problem gambling, assessed by medical record diagnosis and\u002F or Problem Gambling Severity Index (PGSI) score 8\n* Metastatic cancer or enrollment in end of life\u002F palliative care\n* Unable to commit to time commitment required for participation\n* Currently pregnant or planning to become pregnant during the study (people of childbearing potential ages 18-55 who are pregnant or state that they plan to become pregnant during the study)\n* A suicide attempt or suicidal ideation with intent in the 30 days prior to enrollment\n* Concurrent enrollment in a tobacco cessation clinical trial",true,"ALL","18 Years",{"count":94,"type":95},108,"ESTIMATED","INTERVENTIONAL",[98],"NA","Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping Veterans quit smoking during lung cancer screening or cancer care at VA clinics. CM is a behavioral treatment that uses rewards to encourage smoking cessation when verified through biological testing. In the first year, the researchers will develop a mobile CM protocol based on feedback from Veterans and healthcare staff through focus groups. In the second year, they will conduct a pilot study to test the feasibility of the mobile CM program along with counseling and medication for 20 Veterans over a five-week period. The success of the pilot study will determine whether to proceed with a larger randomized controlled trial (RCT) in years three to six, comparing the efficacy of mobile CM with standard treatment. The project will take place at SFVA.",[101,102],"Tobacco Use Disorder","Substance Use Disorder",[104,15,105],"Tobacco","Lung Cancer","2025-09-29",{"date":108,"type":109},"2025-09-30","ACTUAL",{"date":111,"type":109},"2025-01-29",{"date":113,"type":95},"2031-09-30",{"name":5,"class":6},1]