[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607970":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":40,"centralContacts":44,"locations":53,"responsibleParty":71,"collaborators":74,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":31,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":106,"whyStopped":31,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Penn State University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"1 daily yogurt smoothie","EXPERIMENTAL","Children will have the experimental doses of yogurt smoothies (1x daily) for 4 weeks. (93 mL and \\~70 kcal)",[13],"Dietary Supplement: Yogurt Smoothie (1 per day)",{"label":15,"type":10,"description":16,"interventionNames":17},"2 daily yogurt smoothies","Children will have the experimental doses of yogurt smoothies (2x daily) for 4 weeks. (186 mL and \\~140 kcal)",[18],"Dietary Supplement: Yogurt Smoothie (2 per day)",{"label":20,"type":21,"description":22,"interventionNames":23},"daily fruit juice control","ACTIVE_COMPARATOR","Children will have the fruit juice control (1 juice per day) for 4 weeks. (isocaloric fruit juice \\~140 kcal)",[24],"Dietary Supplement: Fruit Juice Control",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DIETARY_SUPPLEMENT","Yogurt Smoothie (1 per day)","Children consume one yogurt smoothie per day for 4 weeks (93 mL and \\~70 kcal).",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Yogurt Smoothie (2 per day)","Children consume two yogurt smoothies per day for 4 weeks (186 mL and \\~140 kcal).",[15],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Fruit Juice Control","Children consume one fruit juice per day for 4 weeks (\\~140 kcal, isocaloric with 2 yogurt smoothie).",[20],[41],{"name":42,"affiliation":5,"role":43},"Kathleen L Keller, Ph.D.","PRINCIPAL_INVESTIGATOR",[45,49],{"name":42,"role":46,"phone":47,"phoneExt":31,"email":48},"CONTACT","814-863-2915","klk37@psu.edu",{"name":50,"role":46,"phone":51,"phoneExt":31,"email":52},"Alaina L Pearce, Ph.D.","814-630-2120","azp271@psu.edu",[54],{"facility":55,"status":31,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"Metabolic Kitchen and Children's Eating Behavior Lab","State College","Pennsylvania","16802","United States","US",{"type":62,"coordinates":63},"Point",[64,65],-77.86,40.79339,{"lat":65,"lon":64},[68,69],{"name":42,"role":43,"phone":31,"phoneExt":31,"email":31},{"name":70,"role":43,"phone":31,"phoneExt":31,"email":31},"Alaina L Pearce, Ph.D",{"type":43,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Kathleen Loralee Keller","Professor in Nutritional Sciences",[75],{"name":76,"class":6},"National Dairy Council","100607970","smoothie-program-for-achieving-and-resilient-kids-100607970",false,"NCT07195474","Smoothie Program for Achieving and Resilient Kids","Effect of Daily Yogurt Smoothies on Neurocognitive Function in Children","SPARK","Inclusion Criteria:\n\n* Children should be of good health, without presence of any metabolic, gastrointestinal, or developmental disorders (e.g., ADHD, autism, etc.).\n* Children should not be taking medications that impact appetite or cognitive function.\n* Children must be willing to consume and report liking the fermented dairy smoothie.\n* Children should be between the ages of 7-9 years-old at enrollment.\n* Children should speak English fluently.\n\nExclusion Criteria:\n\n* They are not within the age requirements (\\\u003C 7 years-old or \\> 9 years-old) at baseline.\n* They have known emotional or cognitive delays, so that we can be assured that they understand the procedures.\n* They do not speak English fluently.\n* They have parentally reported medical problems that affect the digestive system or ability to eat yogurt (e.g., lactose intolerance, food allergies, Crohn's disease, Celiac disease, Esophagitis) and\u002For are taking a prescription medication that may affect appetite (e.g., Ritalin, methylphenidate, Adderall XR, Concerta, Vyvanse, etc.).\n* They are not from families of rural communities (assessed by National Center for Education Statistics local classifications).\n* Their parent is unable to attend the study visits.",true,"ALL","7 Years","9 Years",{"count":90,"type":91},60,"ESTIMATED","INTERVENTIONAL",[94],"NA","The proposed study will examine whether eating yogurt every day can improve brain and gut health in children. Prior research suggests that yogurt may support cognitive functions like self-control, but more studies are needed to confirm this. The study will follow 60 children from Central Pennsylvania, ages 8 to 10, who will be randomly assigned to drink either fruit juice (control group) or yogurt smoothies once or twice a day for four weeks.\n\nResearchers will compare how different amounts of yogurt affect children's thinking skills (like memory and focus), brain activity, and gut bacteria. These changes will be measured through brain scans, computer-based thinking tasks, surveys, and stool samples. The study will also collect information about children's overall diet. The goal is to find out if yogurt can support healthy brain and gut development and to determine the right amount to include in a child's daily diet. Results will help guide future research on how nutrition supports children's health.",[97,98,99],"Executive Functions (EF)","Microbiome","Dietary Quality",[101,102,103,104,105],"Cognitive Function","daily yogurt smoothies intake","gut and brain health","hippocampal-dependent memory","dose-dependent","NOT_YET_RECRUITING","2026-05-18",{"date":109,"type":110},"2026-05-20","ACTUAL",{"date":112,"type":91},"2026-05",{"date":114,"type":91},"2028-09",{"name":5,"class":6},1]