[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583272":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":10,"centralContacts":32,"locations":10,"responsibleParty":38,"collaborators":10,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":10,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":48,"minAge":49,"maxAge":10,"enrollmentInfo":50,"targetDuration":10,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":59,"overallStatus":64,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":10},{"fullName":5,"class":6},"IRCCS Eugenio Medea","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"BMD\u002FDMD group",null,"Patients diagnosed with Duchenne and Becker muscular dystrophy (genetic and histological diagnosis and clinical diagnosis) (ambulant and non-ambulant), over the age of four.",[13,14],"Other: Electroencephalography (EEG)","Other: Social Cognition Tasks",{"label":16,"type":10,"description":17,"interventionNames":18},"OI group","Patients diagnosed with osteogenesis imperfecta, over the age of four.",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Control group","Participants without any neurological or psychiatric disorder, over the age of four.",[13,14],[24,28],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Electroencephalography (EEG)","Recording of resting state EEG will be collected",[9,20,16],{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"Social Cognition Tasks","Comfort-Distance Task: it will be used to measure the interpersonal comfort distance, the task will be implemented in immersive virtual reality environment Interoception will be measured through an auditory match task based on participants heart-beat A measure emotion processing will be collected through the emotion priming visual task, participants will be asked to detect trial by trial the target emotion which could be preceded by a congruent or incongruent visual priming",[9,20,16],[33],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Valentina Nicolardi, PhD","CONTACT","0039 + 3200598331","valentina.nicolardi@lanostrafamiglia.it",{"type":39,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100583272","social-cognition-in-dystrophinopathies-and-neurodevelopmental-disorders-100583272",false,"NCT06874166","Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders","Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders. Behavioural and Psychophisiological Measures","Inclusion Criteria:\n\n* Patients diagnosed with Duchenne and Becker muscular dystrophy (genetic and histological diagnosis and clinical diagnosis) (ambulant and non-ambulant).\n* Patients diagnosed with osteogenesis imperfecta.\n* Control group: participants without any neurological or psychiatric disorder\n\nExclusion Criteria:\n\n* presence of comorbid diagnoses,\n* sensory deficit\n* specific condition that could prevent the application of the tests and tasks under study, such as: a) the need for PEG; b) the need for tracheostomy; c) the need for assisted ventilation.\n* cognitive level lower than 60.",true,"MALE","4 Years",{"count":51,"type":52},45,"ESTIMATED","OBSERVATIONAL","The primary aim of this observational study is to investigate specific aspects of social cognition in dystrophinopathies. Body awareness, interpersonal distance and emotional processing will be measured in a sample of patients affected by Becker (BMD) and Duchenne (DMD) muscular dystrophy, compared with a sample of patients affected by osteogenesis imperfecta (OI), and both compared with a control sample with typical development.\n\nThe secondary aim is to study cortical activity at rest, by means of electroencephalography (EEG), to explore frequencies and time course of EEG responses. Moreover, the relationship between EEG activity and neuropsychological, dispositional and subjective measures will be explored through correlational analyses.",[56,57,58],"Duchenne \u002F Becker Muscular Dystrophy","Osteogenesis Imperfecta (OI)","Social Cognition",[58,60,57,61,62,63],"Duchenne \u002F Becker muscular dystrophy","EEG","Interpersonal distance","Interoception","NOT_YET_RECRUITING","2025-03-11",{"date":67,"type":68},"2025-03-13","ACTUAL",{"date":70,"type":52},"2025-09",{"date":72,"type":52},"2027-12",{"name":5,"class":6}]