[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615551":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":35,"responsibleParty":53,"collaborators":56,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":20,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":37,"whyStopped":20,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University of Pittsburgh","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Adolescents (12-17) with past year STBs and\u002For NSSI.","EXPERIMENTAL","Adolescent aged 12-17 with a past year suicidal thoughts and behaviors (STBs) and\u002For non-suicidal self-injury will complete an EEG task that measures their response to social threat.",[13],"Behavioral: Social threat",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Social threat","EEG Visit:\n\nParticipants will be presented with pictures of female actors with emotional expressions. They will be asked to remember the identities of actors displaying happy, sad, angry, and neutral expressions and tested on their memory. This task examines participants' internal attention to facial cues of emotion while asking them to remember the identities of actors displaying emotional expressions.\n\nEMA Over 30 days, participants will be asked to be report on their social experiences and suicidal thoughts and behaviors three times a day.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Kiera M James, PhD","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},"Kiera M James, Ph.D.","CONTACT","412-634-0004","kij9@pitt.edu",{"name":32,"role":28,"phone":33,"phoneExt":20,"email":34},"Amber Pereira, M.A.","412-353-9329","amp702@pitt.edu",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Pittsburgh","Pennsylvania","15213","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-79.99589,40.44062,{"lat":47,"lon":46},[50,52],{"name":27,"role":28,"phone":51,"phoneExt":20,"email":30},"412-624-8992",{"name":32,"role":28,"phone":33,"phoneExt":20,"email":34},{"type":24,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Kiera James","Research Assistant Professor",[57],{"name":58,"class":59},"National Institute of Mental Health (NIMH)","NIH","100615551","social-threat-adolescent-relationships-and-suicidality-study-100615551",false,"NCT07294079","Social Threat, Adolescent Relationships, and Suicidality Study","Neurocognitive Responses to Social Threat: Links to Day-to-day Connectedness and Suicidality in Adolescent Girls","STARS","Inclusion Criteria:\n\n* Between ages 12-17\n* Reported recurrent suicidal thoughts and behaviors and\u002For non-suicidal self-injury within the past year.\n* Medically and neurologically healthy, including no evidence of intellectual disability or serious cognitive impairment that would interfere with task performance\n* Assigned female at birth\n* Willing and able to give informed assent\n* Own an iPhone\n\nExclusion Criteria:\n\n* Unable to read or speak English or cognitive impairment preventing ability to complete assessments\n* Lifetime presence of a neurological or serious medical condition\n* Lifetime presence of a DSM-5 Autistic Spectrum Disorder\n* Current DSM-5 Psychotic Disorder or severe Substance Use Disorder\n* Uncorrected visual disturbance (\\\u003C20\u002F40 Snellen visual acuity)\n* Presence of head injury or congenital neurological anomalies (based on parent report).","FEMALE","12 Years","17 Years",{"count":72,"type":73},100,"ESTIMATED","INTERVENTIONAL",[76],"NA","In recent years, adolescents are having higher rates of emotional health problems, such as suicidal thoughts and behaviors (STBs). The goal of this study is to learn about how teens' attention to different types of information relates to their real-world relationships and their emotional health. The investigators hope this study will help understand why some teens go on to have suicidal thoughts and behaviors and other teens do not. This information will help investigators learn how to improve emotional health in teens and reduce teen suicides.\n\nParticipants will be 100 female adolescents (ages 12-17) at high risk for STBs who will complete a series of assessments over the course of 6 months. Assessments include a baseline clinical interview, a visit to examine neural responses during a computer tasks, daily smartphone surveys about social experiences and social connectedness, and follow up questionnaires assessing STBs. Participants will also be asked to donate their text messages during the month that they complete smartphone surveys.\n\nThe research procedures will help investigators learn how adolescents react to different types of social situations. Investigators want to see if these reactions affect:\n\n1. How connected adolescents feel to others in their daily lives\n2. Adolescents' longer-term risk for suicidal thoughts and behaviors (STBs)\n\nParticipants will be asked to:\n\n* Complete a 10-15 minute screening call to determine eligibility for the study\n* Complete one 3 hour virtual (or in-person) interview consisting of a clinical assessment and questionnaires.\n* Complete a 2.5-hour in person visit to complete computer tasks while record brain signals are recorded\n* Complete \\~5 minute smartphone surveys three times a day for 30 days, asking about their daily social experiences and their mood and feelings.\n* Provide investigators with retrospective access to their text\u002Fdirect messages from the month the participant was completing the smartphone surveys.\n* Complete online follow-up questionnaires at 3 and 6 months",[79,80,81],"Suicidal Thoughts and Behaviors","Social Connectedness","Responses to Social Threat",[83,84,85,86,87],"Suicide Ideation","Social Threat","EEG","Adolescent","Teen","2026-02-09",{"date":90,"type":91},"2026-02-12","ACTUAL",{"date":93,"type":91},"2026-01-19",{"date":95,"type":73},"2030-08-30",{"name":5,"class":6},1]