[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637527":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":20,"centralContacts":25,"locations":33,"responsibleParty":49,"collaborators":19,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":19,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":36,"whyStopped":19,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University of Padova","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Butimixx","single arm",[12],"Dietary Supplement: Butyrate",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"DIETARY_SUPPLEMENT","Butyrate","Patients will be treated with the ButyMixx , a stick pack probiotic supplement composed sodium butyrate and the yeast Kluyveromyces marxianus, as primary compounds (300 mg and 33.5 mg rispectively).Patients will be asked to take 2 stick packs per day, before meals for 8 weeks.",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Edoardo V Savarino","Università degli Studi di Padova, DiSCOG","PRINCIPAL_INVESTIGATOR",[26,30],{"name":22,"role":27,"phone":28,"phoneExt":19,"email":29},"CONTACT","00390498127749","edoardo.savarinoi@unipd.it",{"name":31,"role":27,"phone":19,"phoneExt":19,"email":32},"Sonia Facchin","sonia.facchin@unipd.it",[34],{"facility":35,"status":36,"city":37,"state":19,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Edoardo Savarino","RECRUITING","Padova","352121","Italy","IT",{"type":42,"coordinates":43},"Point",[44,45],11.14261,44.38225,{"lat":45,"lon":44},[48],{"name":35,"role":27,"phone":19,"phoneExt":19,"email":19},{"type":24,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Savarino Edoardo Vincenzo","Professor","100637527","sodium-butyrate-and-kluyveromyces-marxianus-supplementation-in-inflammatory-bowel-disease-100637527",false,"NCT07591012","Sodium Butyrate and Kluyveromyces Marxianus Supplementation in Inflammatory Bowel Disease","Safety and Tolerability of Sodium Butyrate and Kluyveromyces Marxianus Supplementation in Inflammatory Bowel Disease Treatment","Butymixx","Inclusion Criteria:\n\n* Diagnosis of UC confirmed by clinical, endoscopic and histopathological evidence. Disease in remission phase confirmed by clinical, endoscopic and histopathological evidence.\n* Age between 18 and 75 years old\n* Ability of subject to participate fully in all aspects of this clinical trial.\n\nExclusion Criteria:\n\n* Patients that have active UC, determined by clinical, endoscopic and histopathological evidence\n* Known diagnosis of CD( Crohn disease), indeterminate colitis, ischemic colitis, radiation colitis, diverticular disease associated with colitis or microscopic colitis\n* Positive stool culture for active C. difficile\n* Pregnant women\n* Patients under antibiotic and\u002For probiotic treatment within 10 days prior to Visit 1.","ALL","18 Years","75 Years",{"count":64,"type":65},40,"ESTIMATED","INTERVENTIONAL",[68],"NA","The goal of this clinical trial is to learn if a dietary supplement called ButyMixx can help people with ulcerative colitis in remission feel better and keep their intestines less inflamed.\n\nButyMixx contains:\n\n* Sodium butyrate, a substance normally produced by our gut microbiota that helps protect the intestinal lining and reduce inflammation.\n* A \"beneficial\" yeast (Kluyveromyces marxianus), similar to probiotics, which may support the balance of the intestinal microbiota.\n\nIt will also learn about the safety of dietary supplement. The main questions it aims to answer are:\n\n* Does ButyMixx after 2 months of supplementation\n\n  * Symptoms improve,\n  * Quality of life improves,\n  * Intestinal inflammation decreases ,\n  * The gut microbiota becomes more \"balanced\"\n* What medical problems do participants have when taking ButyMixx ?\n\nParticipants will:\n\n* Take 2 sachets of ButyMixx per day for 8 weeks\n* Before starting and at the end of the 8 weeks:\n\n  * Provide a stool sample\n  * Complete a quality-of-life questionnaire\n  * Be assessed by a doctor using a symptom score",[71],"Ulcerative Colitis (Disorder)",[73,16,74,75],"Ulcerative colitis","Kluyveromyces marxianus","Yearst","2026-05-12",{"date":78,"type":79},"2026-05-15","ACTUAL",{"date":81,"type":65},"2026-05-01",{"date":83,"type":65},"2027-03-30",{"name":5,"class":6},1]