[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635750":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":32,"responsibleParty":46,"collaborators":50,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":25,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":76,"overallStatus":85,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Institute for Human Development and Potential (IHDP), Singapore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mindfulness Condition","EXPERIMENTAL","Participants listen to one 12-minute SOMA Mindfulness audio track randomly assigned from 16 script pairings. Tracks guide bottom-up experiential awareness of everyday sensory and bodily experience (e.g., body scan, mindful walking, mindful eating, awareness of breath). All tracks are narrated by the same voice actor under identical recording conditions.",[13],"Behavioral: SOMA Audio-Guided Mental Training Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Active Control Condition","ACTIVE_COMPARATOR","Participants listen to one 12-minute SOMA Active Control audio track matched to the same practice domain as the assigned Mindfulness track. Tracks guide top-down analytical processing of the same activities (e.g., seating area analysis, spatial navigation exercise, meal organization, weekly schedule optimization). Matched to Mindfulness tracks on duration (±30 seconds), word count (898-957 words), narrator voice, and recording conditions.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","SOMA Audio-Guided Mental Training Exercise","A single 12-minute audio-guided exercise from the Standardized Open-source Mindfulness Architecture (SOMA) library. The SOMA library comprises 88 distinct assets organized around 16 sensory practice modules (formal and informal) paired with structurally equivalent active control scripts. All materials are equity-engineered to a Grade 5-6 reading level, deployable without a meditation teacher, and free under CC BY-NC-SA 4.0 (osf.io\u002Fm76cg).",[15,9],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Alessandro Sparacio, Ph.D. In Psychology","CONTACT","8072 8247","Alessandro_Sparacio@a-star.edu.sg",[33],{"facility":34,"status":25,"city":35,"state":25,"zip":25,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Online","Singapore","SG",{"type":38,"coordinates":39},"Point",[40,41],103.85007,1.28967,{"lat":41,"lon":40},[44],{"name":45,"role":29,"phone":30,"phoneExt":25,"email":31},"Alessandro Sparacio, Ph.D. in Psychology",{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Alessandro Sparacio","Principal Investigator",[51,53],{"name":52,"class":6},"The University of Queensland",{"name":54,"class":6},"Charles University, Czech Republic","100635750","soma-validation-rct-testing-structural-equivalence-and-mechanistic-orthogonality-of-an-open-source-mindfulness-stimulus-library-100635750",false,"NCT07556744","SOMA Validation RCT: Testing Structural Equivalence and Mechanistic Orthogonality of an Open-Source Mindfulness Stimulus Library","The Standardized Open-source Mindfulness Architecture (SOMA): A Modular, Equity-Engineered Stimulus Library for Mechanistic Mindfulness Research","SOMA-VAL","Inclusion Criteria:\n\nAged 18 years or older (or the legal age of majority in the participant's country of residence, whichever is higher)\n\nFluent in English (English as first language or self-reported fluent language)\n\nAble to listen to a 12-minute audio recording with headphones, earphones, or device speaker\n\nAccess to a device capable of completing an online survey\n\nExclusion Criteria:\n\nCurrent diagnosis of a mental health condition\n\nCurrently receiving or waiting for treatment for mental health symptoms (e.g., psychological therapy or psychiatric medication)\n\nRegular yoga or meditation practice in the last six months",true,"ALL","18 Years",{"count":67,"type":68},360,"ESTIMATED","INTERVENTIONAL",[71],"NA","Background: Mindfulness research faces two structural problems. First, weak active control conditions make it impossible to isolate specific mechanisms from expectancy and non-specific effects. Second, most protocols systematically exclude low-socioeconomic status (SES) populations through design assumptions that presuppose high literacy, quiet private spaces, and familiarity with contemplative practice.\n\nObjective: This study validates the Standardized Open-source Mindfulness Architecture (SOMA), the first modular, open-source stimulus library purpose-built to address both challenges simultaneously. SOMA comprises 88 distinct audio assets organized around 16 sensory practice modules, each paired with a structurally equivalent active control script engineered to induce analytically orthogonal cognitive processing.\n\nDesign: Pre-registered randomized controlled trial using a 2×2 mixed design (Condition \\[Mindfulness vs. Active Control\\] × Measure \\[State Mindfulness Scale vs. Analytical Engagement Scale\\]), with quota sampling to ensure equal representation of participants with and without a university-level degree (n = 180 per SES stratum).\n\nSetting: Online, via Prolific Academic recruitment platform and Qualtrics survey software.\n\nParticipants: N = 360 English-proficient adults aged 18 years and older (or the applicable minimum age of majority in the participant's country of residence) without a current mental health diagnosis or treatment, and without a current meditation practice.\n\nIntervention: Each participant listens to a single 12-minute audio-guided exercise. Participants are randomly assigned to either the Mindfulness condition or the Active Control condition, and within that condition to one of 16 practice scripts. Mindfulness scripts guide bottom-up experiential awareness; Active Control scripts guide top-down analytical processing of the same everyday activities.\n\nPrimary Outcomes: (1) Credibility and expectancy equivalence between conditions (H1: Two One-Sided Tests on Credibility and Expectancy Questionnaire composite, equivalence bounds d = ±0.40); (2) mechanistic double dissociation - higher state mindfulness in the Mindfulness condition and higher analytical engagement in the Active Control condition (H2: 2×2 mixed ANOVA, interaction term as primary criterion).\n\nExploratory Outcome: SES-related differential experiential accessibility (H3: independent-samples t-test plus equivalence test on Semantic Differential composite by SES group).",[74,75],"Mindfulness","Healthy Volunteers",[74,77,78,79,80,81,82,83,84],"Active Control","Stimulus Library","Mechanistic Research","Open Science","Socioeconomic Status","Credibility","Expectancy","Randomized Controlled Trial","NOT_YET_RECRUITING","2026-04-28",{"date":88,"type":89},"2026-05-04","ACTUAL",{"date":91,"type":68},"2026-05-05",{"date":93,"type":68},"2026-05-31",{"name":5,"class":6},1]