[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100514142":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":21,"centralContacts":25,"locations":33,"responsibleParty":49,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":10,"enrollmentInfo":59,"targetDuration":62,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":67,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Virginia Commonwealth University","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Asymptomatic carriers",null,[12],"Other: Registry",{"label":14,"type":10,"description":10,"interventionNames":15},"Patients with cardiac hereditary transthyretin amyloidosis (hATTR)",[12],[17],{"type":6,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"Registry","The purpose of this registry is to collect and store health information from people who are carriers of the gene known to cause hereditary amyloidosis and those with a confirmed diagnosis of the disease.",[9,14],[22],{"name":23,"affiliation":5,"role":24},"Keyur Shah, MD","PRINCIPAL_INVESTIGATOR",[26,30],{"name":23,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","804-828-4571","keyur.shah@vcuhealth.org",{"name":31,"role":27,"phone":28,"phoneExt":10,"email":32},"Sarah Paciulli, NP","sarah.paciulli@vcuhealth.org",[34],{"facility":5,"status":10,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Richmond","Virginia","23298","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-77.46026,37.55376,{"lat":44,"lon":43},[47,48],{"name":23,"role":27,"phone":28,"phoneExt":10,"email":29},{"name":23,"role":24,"phone":10,"phoneExt":10,"email":10},{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100514142","southeastern-attr-amyloidosis-consortium-seattrac-family-registry-100514142",false,"NCT05974644","Southeastern ATTR Amyloidosis Consortium: SEATTRAC Family Registry","Inclusion Criteria:\n\n* Over the age of 18 years\n* Carrier of a pathogenic hATTR mutation confirmed on whole blood gene testing or mass spectrometry\n* Willing to return for required follow-up visits\n\nExclusion Criteria:\n\n* Patient having undergone heart transplantation or implantation of mechanical circulatory support\n* Patients unable to provide informed consent\n* Patients having undergone liver transplantation\n* Patients have evidence of light chain amyloidosis","ALL","18 Years",{"count":60,"type":61},1000,"ESTIMATED","3 Years","OBSERVATIONAL","The study design is a prospective registry including asymptomatic and symptomatic patients who carry a pathogenic TTR mutation. The study will enroll patients who meet the inclusion criteria and none of the exclusion criteria until 1000 patients are enrolled, at which point in time the study investigators will evaluate whether further patient accrual is meaningful.",[66],"Amyloidosis, Hereditary","NOT_YET_RECRUITING","2026-06-08",{"date":70,"type":71},"2026-06-09","ACTUAL",{"date":73,"type":61},"2026-07",{"date":75,"type":61},"2030-12-01",{"name":5,"class":6},1]