[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639957":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":22,"responsibleParty":40,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":44,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":10,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":64,"overallStatus":72,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de la Guadeloupe","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"case",null,"subjects of African and Indian ancestry with atypical forms of non autoimmune diabetes.",[13],{"name":14,"affiliation":15,"role":16},"Fritz-Line VELAYOUDOM, Doctor","CHU de la Guadeloupe","PRINCIPAL_INVESTIGATOR",[18],{"name":14,"role":19,"phone":20,"phoneExt":10,"email":21},"CONTACT","0590 89 13 00","fritz-line.velayoudom@chu-guadeloupe.fr",[23],{"facility":5,"status":10,"city":24,"state":25,"zip":26,"country":25,"countryCode":10,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Les Abymes","Guadeloupe","97159",{"type":28,"coordinates":29},"Point",[30,31],-61.50507,16.273,{"lat":31,"lon":30},[34,37],{"name":14,"role":19,"phone":35,"phoneExt":10,"email":36},"0590934686","fritz-line@chu-guadeloupe.fr",{"name":38,"role":19,"phone":35,"phoneExt":10,"email":39},"Eunice NUBRET","eunice.nubret@chu-guadeloupe.fr",{"type":41,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100639957","specificities-of-atypical-non-autoimmune-diabetes-anaid-in-the-french-west-indies-100639957",false,"NCT07576374","Specificities of Atypical Non AutoImmune Diabetes (ANAID) in the French West Indies","Epidemiological, Clinical, Biological and Genetic Specificities of Atypical Non-AutoImmune Diabetes (ANAID) in the French West Indies","DiAGeNA","Inclusion Criteria:\n\nPhenotypic criteria :\n\nSubjects from Indian or African Ancestry self-declared\n\nAge criteria at diagnosis:\n\nEarly onset of diabetes: patient aged between 18 and 47 years at the time of diagnosis of diabetes Clinical criteria: at least 2 criteria Labeled type 2 diabetic\n\nPatient hospitalized for:\n\nKetoacid decompensation Significant weight loss (more than 10% in less than 6 months) without obvious etiology Lipodystrophic \u002F lipoatrophic appearance Presence of an associated myopathy or deafness Presence of early inaugural nephropathy or within 3 years after diagnosis Presence of early inaugural heart disease or within 3 years after diagnosis Poor response to non-insulin treatments despite good adherence\n\nBiological criteria:\n\nAbsent T1D autoantibodies:\n\nAnti-islet antibodies (ICA) Anti-IA2 antibodies Anti-insulin antibodies Anti-ZnT8 antibodies Anti-GAD antibodies\n\nOther criteria:\n\nInformed consent signed by the patient\n\nExclusion Criteria:\n\nType 1 diabetes (T1D) Presence of T1D antibodies Secondary diabetes (pancreas diseases, endocrine diseases, drug intake, infection) Other associated autoimmune pathologies Pregnancy Refusal to participate","ALL","18 Years","47 Years",{"count":54,"type":55},118,"ESTIMATED","OBSERVATIONAL","Genetics variants could be involved in atypical non-autoimmune diabetes revealed by ketoacidosis. The objective of this research will be to determine the relationships between the genetic variants already described in known monogenic diabetes or identified as involved in glucose metabolism and its regulation, in insulin signaling pathways or in insulin secretion itself in subjects of African and Indian ancestry with atypical forms of non autoimmune diabetes.",[59,60,61,62,63],"Metabolic Diseases","Diabetes Mellitus (Type 2)","Genetic Variation","Genetic Profile","Glucose Metabolism Disorders",[65,66,67,68,69,70,71],"Genetic diagnosis","Monogenic diabetes","Exome sequencing","Pathogenic variant","Ketoacidosis","Afro-Caribbean","African and Indian ancestry","NOT_YET_RECRUITING","2026-05-04",{"date":75,"type":76},"2026-05-08","ACTUAL",{"date":78,"type":55},"2026-06",{"date":80,"type":55},"2029-09",{"name":5,"class":6},1]