[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100534918":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":25,"eligibilityCriteria":44,"healthyVolunteers":45,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":25,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":63,"whyStopped":25,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":25},{"fullName":5,"class":6},"Louisiana State University and A&M College","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active high definition transcranial direct current stimulation (HD-tDCS)","EXPERIMENTAL","High-definition anodal transcranial direct current stimulation (2 milliamps \\[mA\\]) for 5 consecutive days (one session per day for 20 minutes each). The electrical current will be administered over the left Supplementary motor area. The stimulation will be delivered at an intensity of 2 milliamps (mA) for a maximum of 20 minutes.",[13],"Device: Active transcranial direct current stimulation",{"label":15,"type":10,"description":16,"interventionNames":17},"Sham high definition transcranial direct current stimulation (HD-tDCS)","High-definition sham transcranial direct current stimulation (2 milliamps \\[mA\\]) for 5 consecutive days (one session per day for 20 minutes each). The electrical current will be administered over the left Supplementary motor area. The current will be ramped up for the first 30 seconds following which the intensity will drop to 0 milliamps (mA).",[18],"Device: Sham transcranial direct current stimulation",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Active transcranial direct current stimulation","HD electrodes (diameter of 1.2 cm) will be placed on the participants' skull using an HD-tDCS cap (Soterix Medical Inc. New York) and based on 5-10 international montage. Active stimulations will be delivered by a 9 MxN Soterix HD-tES device for 20 minutes( 2 mA) per day for 5 days.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Sham transcranial direct current stimulation","HD electrodes (diameter of 1.2 cm) will be placed on the participants' skull using an HD-tDCS cap (Soterix Medical Inc. New York) and based on 5-10 international montage. Sham stimulations will be delivered by a 9 MxN Soterix HD-tES device. In the sham tDCS condition, the current is only on for 30 seconds before it is ramped back down to 0 milliamps (mA), although the electrodes are still worn for 20 minutes.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Karim Johari","CONTACT","225-578-3934","karimjohari@lsu.edu",{"type":37,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100534918","speech-and-voice-outcomes-following-hd-tdcs-over-the-left-sma-100534918",false,"NCT06245070","Speech and Voice Outcomes Following HD-tDCS Over the Left SMA","Immediate and Short-term Effects of High-definition Transcranial Direct Current Stimulation Over the Left Supplementary Motor Area on Voice and Speech Functions in Parkinson's Disease","Inclusion Criteria:\n\n* Clinical diagnosis of Parkinson's disease\n* Native English speakers\n* Adequate age-relative hearing and vision to perform the outlined tasks\n* Able to provide their own written consent\n\nExclusion Criteria :\n\n* Neurological disorders besides Parkinson's disease\n* Previous brain surgery including deep brain stimulation\n* Clinical diagnosis of dementia",true,"ALL","18 Years","80 Years",{"count":50,"type":51},48,"ESTIMATED","INTERVENTIONAL",[54],"NA","Pharmaceutical and neurosurgical treatments reliably ameliorate the cardinal motor symptoms in PD but, they often yield inconsistent outcomes for speech and voice disorders, with some studies showing exacerbation of pre-treatment deficits. Therefore, it is crucial to develop and optimize novel approaches that could simultaneously improve speech and voice deficits in PD and facilitate existing behavioral interventions. This project will investigate the immediate and short-term effects of multiple sessions of HD-tDCS over the left SMA on speech and voice deficits in PD.",[57],"Parkinson Disease",[59,60,61,62],"Brain stimulation","Supplementary motor area","Speech","Voice","NOT_YET_RECRUITING","2024-02-23",{"date":66,"type":67},"2024-02-26","ACTUAL",{"date":69,"type":51},"2025-02-02",{"date":71,"type":51},"2028-06-02",{"name":5,"class":6}]