[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100577641":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":33,"responsibleParty":52,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":63,"maxAge":10,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":70,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Istituto Auxologico Italiano","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Anorexia Nervosa",null,"Adult female Anorexia Nervosa patients, hospitalized at the Division of Eating and Nutrition Disorders (END), Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy",[13],"Other: Determination of sphingolipidomic profile",{"label":15,"type":10,"description":16,"interventionNames":17},"Normal weight","Adult normal-weight women with a Body Mass Index between 18.5 and 24.9 kg\u002Fm2, recruited from research and hospital staff",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Determination of sphingolipidomic profile","The plasma\u002Fserum levels of the following sphingolipids will be measured: ceramides and dihydroceramides from C16 to C24, including 2 unsaturated ones (C18:1 and C24:1), sphingomyelins (those from C16 to C24 and the one C24:1), sphingosine, sphinganine, sphingosine-1-phosphate and sphinganine-1-phosphate.",[9,15],[24,30],{"name":25,"role":26,"phone":27,"phoneExt":28,"email":29},"Alessandro Sartorio, MD","CONTACT","+390261911","2426","sartorio@auxologico.it",{"name":31,"role":26,"phone":27,"phoneExt":10,"email":32},"Luca Grappiolo, Dr.","luca.grappiolo@auxologico.it",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Istituto Auxologico Italiano IRCCS, Site Piancavallo","RECRUITING","Oggebbio","Verbania","28824","Italy","IT",{"type":43,"coordinates":44},"Point",[45,46],8.64663,45.99088,{"lat":46,"lon":45},[49],{"name":50,"role":26,"phone":51,"phoneExt":28,"email":29},"Alessandro Sartorio","+39-02619111",{"type":53,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100577641","sphingolipidomic-profile-in-anorexia-nervosa-100577641",false,"NCT06800937","Sphingolipidomic Profile in Anorexia Nervosa","Evaluation of the Sphingolipidomic Profile in Women Suffering From Anorexia Nervosa: Relationship With Clinical-endocrine and Psychiatric Parameters","SFINGOANNER","Patients with Anorexia Nervosa:\n\nInclusion Criteria:\n\n* Female sex\n* Age: 18 years or older\n* Diagnosis of Anorexia Nervosa in the acute phase\n* Hospitalized at the Division of Eating and Nutrition Disorders (END), San Giuseppe Hospital, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy\n\nExclusion Criteria:\n\n* Absence of signed Informed Consent\n\nControl group:\n\nInclusion Criteria:\n\n* Female sex\n* Age: 18 years or older\n* BMI between 18.5 and 24.9 kg\u002Fm2\n\nExclusion Criteria:\n\n* Absence of signed Informed Consent","FEMALE","18 Years",{"count":65,"type":66},60,"ESTIMATED","OBSERVATIONAL",": The objective of this research project will be to determine the sphingolipidomic profile in a group of women (\\> 18 years) affected by Anorexia Nervosa (AN), phenotypically characterized (restricting \\[AN-R\\] vs binge-eating purging \\[AN-BP\\]). Specific questionnaires will be administered for the definition of the severity of the eating disorder and depressive state (suicidality), to which will be added the evaluation of gonadal function (i.e., plasma levels of estradiol\u002Fprogesterone and use of oral contraceptives).\n\nBased on the specific lipidomic profile, which the present research project hopes to characterize, it will be possible to appropriately modify the diet of rehabilitation programs and, in the future, improve the effectiveness of the treatment itself, especially in the long term.",[9],[71,72,73,74],"Anorexia nervosa","Sphingolipids","Females","Lipidomic profile","2026-03-25",{"date":77,"type":78},"2026-03-30","ACTUAL",{"date":80,"type":78},"2024-06-19",{"date":82,"type":66},"2026-06-30",{"name":5,"class":6},1]