[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583048":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":36,"responsibleParty":54,"collaborators":56,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":31,"enrollmentInfo":80,"targetDuration":31,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":31,"overallStatus":39,"whyStopped":31,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"University of Melbourne","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"RRULI: Appendix 1","EXPERIMENTAL","In this first arm of SCINC, adults with chronic tetraplegia will be assigned to the RRULI: Appendix 1 intervention.",[13],"Other: Therapeutic Intermittent Hypoxia (TIH) + Exercise Training (ET)",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Therapeutic Intermittent Hypoxia (TIH) + Exercise Training (ET)","TIH in combination with upper limb and respiratory ET. The intervention is predominantly home-based and will be delivered three times per week for six weeks.",[9],[20,21],"Therapeutic acute intermittent hypoxia (tAIH)","Acute intermittent hypoxia (AIH)",[23],{"name":24,"affiliation":5,"role":25},"David Berlowitz, PhD","PRINCIPAL_INVESTIGATOR",[27,33],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Laura Stendell","CONTACT","(+61) 468 862 693",null,"laura.stendell@unimelb.edu.au",{"name":34,"role":29,"phone":31,"phoneExt":31,"email":35},"Nicole Sheers, PhD","nsheers@unimelb.edu.au",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Austin Health","RECRUITING","Heidelberg","Victoria","3084","Australia","AU",{"type":46,"coordinates":47},"Point",[48,49],145.06667,-37.75,{"lat":49,"lon":48},[52],{"name":28,"role":29,"phone":53,"phoneExt":31,"email":32},"(+61) 0468 862 693",{"type":55,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR",[57,60,62,64,66,68],{"name":58,"class":59},"Institute of Breathing and Sleep","UNKNOWN",{"name":38,"class":61},"OTHER_GOV",{"name":63,"class":6},"Neuroscience Research Australia",{"name":65,"class":6},"The University of New South Wales",{"name":67,"class":6},"University of Sydney",{"name":69,"class":6},"University of Florida","100583048","spinal-cord-injury-neurorecovery-collaboration-100583048",false,"NCT06871254","Spinal Cord Injury Neurorecovery Collaboration","Spinal Cord Injury Neurorecovery Collaboration (SCINC) Master Protocol","SCINC","SCINC Inclusion Criteria:\n\n\\- Person with SCI\n\nSCINC Exclusion Criteria:\n\n\\- Proven contraindication to intervention\n\nRRULI: Appendix 1 (TIH + ET) study-specific inclusion criteria:\n\n* Adults \\> 18 years of age\n* Able to independently ventilate\n* Chronic SCI (\\>1 years post-injury or impairment onset)\n* Tetraplegia (C2-T1 level of injury)\n* Evidence of motor incomplete paralysis in the upper limb below the neurological level of injury\n* Have a documented management plan for their AD if it occurs.\n\nRRULI: Appendix 1 (TIH + ET) study-specific exclusion criteria:\n\n* Pregnancy\n* Medical instability, including current or recent (within the previous 6 weeks) infection or inflammation\n* Current or recent (within the previous 6 weeks) pressure ulcers or cutaneous lesions\n* Poorly controlled diabetes\n* An episode of AD in the previous 6 months that required medical intervention to resolve\n* Significant other neurological, psychiatric, pulmonary, cardiovascular, orthopaedic, or oncological conditions.\n* Currently taking part in another clinical trial\n* Upper limb contracture","ALL","18 Years",{"count":81,"type":82},24,"ESTIMATED","INTERVENTIONAL",[85],"NA","SCINC is an adaptive design Master protocol that seeks to determine if there is \"sufficient promise\" of beneficial effect of treatment combinations to enhance motor recovery in pre-specified strata of people with a spinal cord injury.",[88],"Spinal Cord Injuries","2025-08-04",{"date":91,"type":92},"2025-08-08","ACTUAL",{"date":94,"type":92},"2025-03-01",{"date":96,"type":82},"2027-12-31",{"name":5,"class":6},1]