[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100564846":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":10,"responsibleParty":34,"collaborators":10,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":10,"eligibilityCriteria":44,"healthyVolunteers":40,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":10,"studyType":51,"phases":10,"briefSummary":52,"conditions":53,"keywords":56,"overallStatus":60,"whyStopped":10,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":66,"leadSponsor":68,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"control group",null,"This group include healthy volunteers who aged ≥ 40 years .",[13],"Device: ultrasound, spirometry",{"label":15,"type":10,"description":16,"interventionNames":17},"study group","This include stable COPD Patients who will be diagnosed by GOLD 2024 and last excerbation ≥ 6weeks .",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DEVICE","ultrasound, spirometry","Ultrasound assessment of\n\n1. diaphragmatic excursion:-the probe will be angled medially ,cranially , and dorsally so that the ultrasound beam reaches the posterior third of the diaphragm, in B-mode.Then, then M-mode exploration line will be placed perpendicular to the diaphragmatic dome to obtain maximum excursion .\n2. (Tdi) will be measured using a high-frequency linear probe (10 MHz) placed on (ZA).The probe will be angled perpendicular to the lateral chest wall and placed between the midaxillary and anterior axillary lines at the eighth or ninth intercostal space.\n3. Quadricep\\|rectus femoris muscle assessment will be done by placing the transducer perpendicular to the long axis of the thigh.\n\n   * Spirometry:-will be performed thrice by experienced technicians at our pulmonary function laboratory. Patients will be asked to take a maximal inspiration and then to forcefully expel air for as long and as quickly as possible.",[9,15],[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Safaa Mohamed Shazly, resident doctor","CONTACT","01228942380","drsafaashazly@gmail.com",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Hoda Ahmed Makhlouf, professor","01001529442","hamakhlouf@aun.edu.eg",{"type":35,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Safaa Mohamed Shazly","Principal Investigator","100564846","spirometry-diaphragmatic-ultrasound-and-skeletal-muscle-mass-in-patients-with-chronic-obstructive-pulmonary-disease-100564846",false,"NCT06634485","Spirometry ,diaphragmatic Ultrasound and Skeletal Muscle Mass in Patients with Chronic Obstructive Pulmonary Disease","Correlation Between Spirometry ,diaphragmatic Ultrasound and Skeletal Muscle Mass in Patients with Chronic Obstructive Pulmonary Disease : Case Control Study","Inclusion Criteria:\n\n* Group A (control group):\n\n  * This group include healthy volunteers who aged ≥ 40 years .\n* Group B (study group):\n\n  * This include stable COPD Patients who will be diagnosed by GOLD 2024 and last excerbation ≥ 6weeks .\n\nExclusion Criteria:\n\n* Group A (control group):\n\n  * Patients with disorders that may affect diaphragmatic function as\n\n    1. Musculoskeletal \u002F neurological disorders\n    2. diaphragmatic eventration \\\\ hiatus hernia\n    3. morbid obesity\n    4. recent thoracic\u002Fabdominal surgeries\n    5. pregnancy; pleurodesis \\\\fibrothorax.\n* Group B (study group):-\n\n  * Patients need for non- invasive ventilation.\n  * Patients with disorders that may affect diaphragmatic function as\n\n    1. Musculoskeletal \u002F neurological disorders\n    2. diaphragmatic eventration \\\\ hiatus hernia\n    3. morbid obesity\n    4. recent thoracic\u002Fabdominal surgeries\n    5. pregnancy; pleurodesis \\\\fibrothorax","MALE","41 Years","70 Years",{"count":49,"type":50},64,"ESTIMATED","OBSERVATIONAL","* The primary objective is to evaluate the use of diaphragmatic function and skeletal muscle mass by ultrasound as a tool to establish the diagnosis of COPD and assess the severity of the disease.\n* The secondary objective is to compare diaphragmatic function, Skeletal muscle mass, and spirometry results in patients with COPD.",[54,55],"COPD","Ultrasound Therapy; Complications",[54,57,58,59],"Diaphragmatic Ultrasound","Spirometry","Skeletal Muscle Mass","NOT_YET_RECRUITING","2024-10-08",{"date":63,"type":64},"2024-10-10","ACTUAL",{"date":63,"type":50},{"date":67,"type":50},"2026-12-20",{"name":5,"class":6}]