[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641134":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":49,"responsibleParty":73,"collaborators":44,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":77,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":44,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":99,"overallStatus":105,"whyStopped":44,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Cumhuriyet University Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"SPSIP Block Group","EXPERIMENTAL","Participants in this arm will receive bilateral ultrasound-guided serratus posterior superior intercostal plane block after induction of general anesthesia and before surgical local infiltration and skin incision. They will also receive standard general anesthesia, standardized surgical local anesthetic infiltration, and standard postoperative multimodal pain treatment.",[13,14],"Procedure: Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block","Other: Standard Perioperative Pain Treatment",{"label":16,"type":17,"description":18,"interventionNames":19},"Control Group","ACTIVE_COMPARATOR","Participants in this arm will receive standard general anesthesia, standardized surgical local anesthetic infiltration, and standard postoperative multimodal pain treatment. They will not receive serratus posterior superior intercostal plane block.",[14],[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block","Bilateral ultrasound-guided serratus posterior superior intercostal plane block will be performed after induction of general anesthesia and before surgical local anesthetic infiltration and skin incision.",[9],[27],"SPSIP block",{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Standard Perioperative Pain Treatment","Participants will receive standard general anesthesia, standardized surgical local anesthetic infiltration, and standard postoperative multimodal pain treatment with rescue analgesia when clinically needed.",[16,9],[33],"Standard anesthesia and postoperative analgesia",[35],{"name":36,"affiliation":37,"role":38},"Handan Derebaşınlıoğlu, Associate Professor","Cumhuriyet University","STUDY_DIRECTOR",[40,46],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},"Murat Çelik, Assistant Professor","CONTACT","+905546902104",null,"mucetr@gmail.com",{"name":36,"role":42,"phone":47,"phoneExt":44,"email":48},"(0346) 258 00 00","hastane@cumhuriyet.edu.tr",[50],{"facility":51,"status":44,"city":52,"state":52,"zip":53,"country":54,"countryCode":44,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Sivas Cumhuriyet University","Sivas","58050","Turkey (Türkiye)",{"type":56,"coordinates":57},"Point",[58,59],37.01611,39.74833,{"lat":59,"lon":58},[62,65,69,71],{"name":63,"role":42,"phone":64,"phoneExt":44,"email":45},"Murat Çelik","05546902104",{"name":66,"role":42,"phone":67,"phoneExt":44,"email":68},"Onur Avcı, Associate Professor","90 530 112 64 08","dronuravci@gmail.com",{"name":41,"role":70,"phone":44,"phoneExt":44,"email":44},"PRINCIPAL_INVESTIGATOR",{"name":66,"role":72,"phone":44,"phoneExt":44,"email":44},"SUB_INVESTIGATOR",{"type":70,"investigatorFullName":63,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":44,"oldOrganization":44},"Assistant Professor","100641134","spsip-block-for-pain-control-after-breast-reduction-surgery-100641134",false,"NCT07657949","SPSIP Block for Pain Control After Breast Reduction Surgery","Effect of Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block on Opioid Consumption After Reduction Mammaplasty: A Prospective Randomized Controlled Trial","SPSIP-RM","Inclusion Criteria:\n\n* Female participants aged 18 to 65 years\n* Scheduled for elective bilateral reduction mammaplasty\n* Planned surgery under general anesthesia\n* American Society of Anesthesiologists physical status class I to III\n* Planned postoperative clinical follow-up for the first 24 hours after surgery\n* Able to understand and report pain using the 0 to 10 Numeric Rating Scale\n* Able to provide written informed consent for study participation\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to local anesthetic drugs\n* Contraindication to regional anesthesia or fascial plane block\n* Coagulopathy or clinically significant bleeding disorder\n* Use of anticoagulant or antiplatelet medication that prevents safe block application\n* Infection at the planned block injection site\n* Chronic opioid use, chronic pain syndrome, or regular analgesic use that may affect postoperative pain assessment\n* Revision breast surgery\n* Planned major additional surgical procedure other than reduction mammaplasty\n* Pregnancy or lactation\n* Unable to reliably report pain scores","FEMALE","18 Years","65 Years",{"count":87,"type":88},80,"ESTIMATED","INTERVENTIONAL",[91],"NA","The goal of this clinical trial is to learn whether an ultrasound-guided serratus posterior superior intercostal plane block (SPSIP block) can lower the need for opioid pain medicine after breast reduction surgery.\n\nThe main question it aims to answer is: Does adding an SPSIP block to standard anesthesia and pain treatment lower opioid use during the first 24 hours after surgery? Researchers will compare participants who receive standard anesthesia and pain treatment with participants who receive standard anesthesia and pain treatment plus an SPSIP block.\n\nParticipants will:\n\n* Have planned bilateral breast reduction surgery under general anesthesia\n* Be randomly assigned to the SPSIP block group or the control group\n* Receive standard local anesthetic infiltration during surgery and standard pain treatment after surgery\n* Have their pain score and pain medicine use recorded during the first 24 hours after surgery\n* Be followed for safety and complications for 30 days after surgery",[94,95,96,97,98],"Postoperative Pain Breast Reduction","Mammaplasty","Analgesia","Nerve Block","Opioid Consumption, Postoperative",[100,101,102,103,104],"Serratus posterior superior intercostal plane block","Ultrasound-guided regional anesthesia","Reduction mammaplasty","Breast reduction surgery","Postoperative pain","NOT_YET_RECRUITING","2026-06-14",{"date":108,"type":109},"2026-06-18","ACTUAL",{"date":111,"type":88},"2026-08-01",{"date":113,"type":88},"2027-08-31",{"name":5,"class":6},1]