[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100537175":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":57,"collaborators":60,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":78,"sex":84,"minAge":85,"maxAge":25,"enrollmentInfo":86,"targetDuration":25,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":96,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Beijing Anzhen Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standby cannulated ECMO","EXPERIMENTAL","For standby cannulated ECMO procedures, femoral cannulas are inserted either by percutaneous approach or surgical approach. The primed circuit is connected to the inserted ECMO cannulas, clamps are kept on circuit, and ECMO is on standby during PCI. When PCI cause hemodynamic instability, clamps on circuit are removed, and VA-ECMO is initiated to maintain maintain adequate systemic pressure and perfusion.",[13],"Procedure: Standby cannulated ECMO",{"label":15,"type":16,"description":17,"interventionNames":18},"Prophylactic ECMO","ACTIVE_COMPARATOR","Prophylactic ECMO procedures are performed in the catheterization laboratory before PCI. Femoral cannulas are inserted either by percutaneous approach or surgical approach. Following cannula placement, VA-ECMO is initiated to maintain adequate systemic pressure and perfusion during PCI.",[19],"Procedure: Prophylactic ECMO",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Femoral cannulas are inserted and connected to the primed circuit. Clamps are kept on circuit, and ECMO is on standby during PCI. ECMO is initiated if needed.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Prophylactic ECMO procedures are performed in the catheterization laboratory before PCI.",[15],[30],{"name":31,"affiliation":5,"role":32},"Xiaotong Hou, MD","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","010-64456631","xt.hou@ccmu.edu.cn",[39],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Beijing","Beijing Municipality","100029","China","CN",{"type":47,"coordinates":48},"Point",[49,50],116.39723,39.9075,{"lat":50,"lon":49},[53],{"name":54,"role":35,"phone":55,"phoneExt":25,"email":56},"Liangshan Wang, MD","86-13811363372","wangliangshanbam@sina.com",{"type":32,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Xiaotong Hou","Professor",[61,63,65,67,69,72,74],{"name":62,"class":6},"Wuhan Asia Heart Hospital",{"name":64,"class":6},"First Affiliated Hospital of Harbin Medical University",{"name":66,"class":6},"People's Hospital of Xinjiang Uygur Autonomous Region",{"name":68,"class":6},"People's Hospital of Guangxi Zhuang Autonomous Region",{"name":70,"class":71},"The First Affiliated Hospital of Lanzhou Medical University","UNKNOWN",{"name":73,"class":6},"Chinese Academy of Medical Sciences, Fuwai Hospital",{"name":75,"class":6},"The Second Affiliated Hospital of Harbin Medical University","100537175","standby-cannulated-ecmo-for-high-risk-percutaneous-coronary-intervention-100537175",false,"NCT06274411","Standby Cannulated ECMO for High-Risk Percutaneous Coronary Intervention","Standby Cannulated ECMO Versus Prophylactic ECMO In Patients Undergoing High-Risk Percutaneous Coronary Intervention","ECMO-READY","Inclusion Criteria:\n\n1. Clinicians decide to perform PCI during ECMO support.\n2. Age of ≥18\n3. Patient presents with a compromised ejection fraction of less than 35% or at risk of hemodynamic deterioration, or intervention on the last patent coronary conduit or an unprotected left main artery, or complex 3-vessel disease (SYNTAX score of ≥33)\n4. Informed consent\n\nExclusion Criteria:\n\n1. Subject in cardiogenic shock(need inotrope, pressor or mechanical support to maintain SBP \\>90mmHg)\n2. Presence of moderate to severe aortic insufficiency\n3. Severe peripheral vascular disease\n4. creatinine≥4mg\u002FdL\n5. Liver dysfunction with elevation of liver enzymes and bilirubin levels to ≥ 3x ULN\n6. History of recent (within 1 month) stroke or TIA\n7. Abnormal coagulation(defined as platelet count ≤50000\u002Fmm3 or Fibrinogen ≤1.50g\u002FL)\n8. Allergy or intolerance to heparin, aspirin, ADP receptor inhibitors, or documented heparin induced thrombocytopenia.","ALL","18 Years",{"count":87,"type":88},176,"ESTIMATED","INTERVENTIONAL",[91],"NA","The goal of this multicenter, randomized trial is to compare standby cannulated ECMO versus prophylactic ECMO in patients undergoing high-risk percutaneous coronary intervention (PCI). The main question it aims to answer is :\n\n• If standby cannulated ECMO as compared with prophylactic ECMO will improve the outcomes in patients undergoing high-risk PCI",[94,95],"ECMO","High-risk PCI",[94,97],"PCI","2026-05-10",{"date":100,"type":101},"2026-05-13","ACTUAL",{"date":103,"type":101},"2025-03-21",{"date":105,"type":88},"2026-12-01",{"name":5,"class":6},1]