[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599147":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":30,"responsibleParty":62,"collaborators":19,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":19,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":19,"enrollmentInfo":74,"targetDuration":19,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":33,"whyStopped":19,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"University Ghent","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Immediate implant placement","EXPERIMENTAL","State of the art immediate implant placement with socket grafting and soft tissue augmentation.",[13],"Procedure: Immediate implant placement",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"PROCEDURE","Immediate implant placement with socket grafting and soft tissue augmentation. In cases with a buccal dehiscence \\>3mm only this technique is applied. In cases with a buccal dehiscence between 4-6mm a collagen membrane is applied prior to socket grafting. In cases with a buccal dehiscence \\> 6 mm, a collagen membrane is also applied and a mixture of C-DBBM and autogenous bone chips (1:1 ratio) is used as grafting material.",[9],null,[21,26],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Véronique Christiaens, Phd","CONTACT","09\u002F332 40 17","vchristi.christiaens@UGent.be",{"name":27,"role":23,"phone":28,"phoneExt":19,"email":29},"Jan Cosyn, PhD","09\u002F332 40 18","jan.cosyn@UGent.be",[31,48],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Ghent University","RECRUITING","Ghent","East Flanders","9000","Belgium","BE",{"type":40,"coordinates":41},"Point",[42,43],3.71667,51.05,{"lat":43,"lon":42},[46],{"name":47,"role":23,"phone":24,"phoneExt":19,"email":25},"Véronique Christiaens, PhD",{"facility":49,"status":33,"city":50,"state":35,"zip":51,"country":37,"countryCode":38,"cosmosGeoPoint":52,"geoPoint":56,"contacts":57},"Bv Dr. Cosyn","Zottegem","9620",{"type":40,"coordinates":53},[54,55],3.81052,50.86955,{"lat":55,"lon":54},[58],{"name":59,"role":23,"phone":60,"phoneExt":19,"email":61},"Jan Cosyn, Prof. Dr.","0496 10 01 21","jan.cosyn@ugent.be",{"type":63,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100599147","state-of-the-art-immediate-implant-placement-in-the-premaxilla-100599147",false,"NCT07080710","State of the Art Immediate Implant Placement in the Premaxilla","A Clinical Study on Immediate Implant Placement in the Premaxilla With Flapless Guided Surgery, Hard and Soft Tissue Augmentation and Immediate Provisionalization","Inclusion Criteria:\n\n* At least 20 years old\n* Good oral hygiene defined as full-mouth plaque score ≤ 25%\n* Presence of one or more incisors, cuspids or premolars in the maxilla that need to be extracted for any reason with at least one neighboring tooth present\n* At least 3 mm bone available at the apical or palatal aspect of the alveoli as assessed on a three-dimensional radiograph to ensure primary implant stability\n* Written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy (will be explicitly asked)\n* Systemic diseases\n* Smoking; suppuration\n* \\> 1 mm gingival asymmetry between the failing teeth and contralateral teeth\n* Failing teeth outside the bone envelop as assessed on a three-dimensional radiograph\n* Untreated periodontal disease; untreated caries lesions.",true,"ALL","20 Years",{"count":75,"type":76},50,"ESTIMATED","INTERVENTIONAL",[79],"NA","The goal of this clinical study is to learn how well immediate implant placement works in the front upper jaw (premaxilla) when using flapless guided surgery, hard and soft tissue augmentation, and immediate provisional crowns. It will also learn about the safety and esthetic results of this treatment approach.\n\nThe main questions it aims to answer are:\n\nPrimary:\n\nHow much buccal bone thickness remains one year after implant placement 1mm below the implant shoulder?\n\nSecondary:\n\n* How do patients rate pain, healing, and esthetics after treatment?\n* Are there any complications over the course of five years?\n* How much buccal bone thickness remains one year after implant placement 3mm and 5mm below the implant shoulder?\n* Marginal bone loss at one-year and five-year follow-up?\n* Peri-implant health at one-year and five-year follow-up?\n* Soft tissue changes at one-year and five-year follow-up?\n\nResearchers will compare treatment results in patients with intact bone sockets to those with damaged (non-intact) sockets.\n\nParticipants will:\n\n* Receive a dental implant and temporary crown on the same day as the tooth extraction\n* Undergo guided, flapless surgery with bone and soft tissue grafting\n* Take antibiotics and anti-inflammatories for 4 days after surgery\n* Visit the clinic at 1 week, 3 months, 1 year, and 5 years for follow-up exams\n* Have X-rays, digital scans, and photos taken to measure bone and soft tissue changes\n* Answer questions about pain and esthetic satisfaction",[82],"Bone Resorption",[84,85,86,87,88,89],"dental implant, single-tooth","Immediate","connective tissue graft","socket grafting","intact alveolus","non-intact alveolus","2025-11-14",{"date":92,"type":93},"2025-11-18","ACTUAL",{"date":95,"type":93},"2025-07-01",{"date":97,"type":76},"2032-02-01",{"name":5,"class":6},2]