[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560046":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":20,"responsibleParty":36,"collaborators":39,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":7,"eligibilityCriteria":58,"healthyVolunteers":55,"sex":59,"minAge":7,"maxAge":7,"enrollmentInfo":60,"targetDuration":63,"studyType":64,"phases":7,"briefSummary":65,"conditions":66,"keywords":7,"overallStatus":22,"whyStopped":7,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"IRCCS Fondazione Stella Maris","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Filippo M Santorelli, Dr.","PRINCIPAL_INVESTIGATOR",[13,17],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},"CONTACT","+39 050886275","filippo.santorelli@fsm.unipi.it",{"name":18,"role":14,"phone":7,"phoneExt":7,"email":19},"Sara Satolli, Dr.","sara.satolli@fsm.unipi.it",[21],{"facility":5,"status":22,"city":23,"state":7,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"RECRUITING","Pisa","56128","Italy","IT",{"type":28,"coordinates":29},"Point",[30,31],10.4036,43.70853,{"lat":31,"lon":30},[34,35],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},{"name":18,"role":14,"phone":7,"phoneExt":7,"email":19},{"type":11,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Filippo Maria Santorelli","Director of Molecular Medicine",[40,42,45,47,49,51],{"name":41,"class":6},"IRCCS Eugenio Medea",{"name":43,"class":44},"Università degli studi di Messina","UNKNOWN",{"name":46,"class":6},"IRCCS Istituto delle Scienze Neurologiche di Bologna",{"name":48,"class":6},"Catholic University of the Sacred Heart",{"name":50,"class":44},"CINECA",{"name":52,"class":6},"Fondazione Telethon","100560046","stop-hspnet-a-registry-for-hereditary-spastic-paraplegia-as-an-integration-tool-for-future-therapeutic-strategies-100560046",false,"NCT06572046","STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic Strategies","Inclusion Criteria:\n\n* clinical diagnosis of pure or complex HSP\u002Fspastic ataxia, even in the absence of a known genetic diagnosis\n* participants\u002Fparents\u002Flegal guardians will have to give informed consent for enrollment in the registry and privacy data management\n\nExclusion Criteria:\n\n* subjects affected by secondary forms of HSP\n* presenting comorbidities that affect the general clinical picture according to clinical judgment\n* lack of informed consent","ALL",{"count":61,"type":62},500,"ESTIMATED","15 Years","OBSERVATIONAL","Our goal is to create a solid and harmonious disease registry of patient affected by hereditary spastic paraplegia (HSP) that facilitates the collection and management of patients' data over time encouraging the research and the development of future clinical trials. In-depth clinical phenotyping will develop significant clinical outcome measures that can be used in clinical trials and will allow the phenotypic complexity of the disease to be captured with the use of validated clinical scales, biomarkers and so-called patient reported outcomes (PROs).",[67],"Hereditary Spastic Paraplegia","2026-03-23",{"date":70,"type":71},"2026-03-27","ACTUAL",{"date":73,"type":71},"2024-01-24",{"date":75,"type":62},"2029-12-31",{"name":5,"class":6},1]