[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597855":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":20,"centralContacts":25,"locations":35,"responsibleParty":58,"collaborators":61,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":19,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":19,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":38,"whyStopped":19,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Universidad de los Andes, Chile","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Single arm with the stratified-care intervention Reframe-IT and CARIBOU","single arm",[12],"Behavioral: Reframe-IT and CARIBOU",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"BEHAVIORAL","Reframe-IT and CARIBOU","Reframe-IT+ An individual intervention based on cognitive-behavioral therapy (CBT) focused on developing skills in behavioral activation, cognitive restructuring, emotion regulation, stress tolerance, and problem-solving. It is delivered in the school setting by a trained psychologist from the research team. The program consists of 13 weekly sessions of 45 minutes each: 5 face-to-face sessions and 8 combined digital\u002Fin-person sessions where students use a computer under the supervision of a psychologist facilitator.\n\nCARIBOU An individual CBT-based intervention focused on behavioral activation, cognitive restructuring, problem-solving, and communication skills. It is conducted in the school setting by a trained psychologist and consists of 16 weekly sessions of 45 minutes each.",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Jorge E Gaete, MD. PhD.","Universidad de Los Andes","STUDY_DIRECTOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},"Jorge E Gaete, MD, PhD","CONTACT","+56940245650","jgaete@uandes.cl",{"name":32,"role":28,"phone":33,"phoneExt":19,"email":34},"Saray A Ramírez, MsC","+56988191548","saramirez1@miuandes.cl",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":19,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Universidad de los Andes","RECRUITING","Santiago","Las Condes","Chile","CL",{"type":44,"coordinates":45},"Point",[46,47],-70.64827,-33.45694,{"lat":47,"lon":46},[50,52,56],{"name":51,"role":28,"phone":33,"phoneExt":19,"email":34},"Saray A Ramírez, MsC.",{"name":53,"role":28,"phone":54,"phoneExt":19,"email":55},"Valentina R Romo, MsC","+56984038329","vromo@miuandes.cl",{"name":22,"role":57,"phone":19,"phoneExt":19,"email":19},"PRINCIPAL_INVESTIGATOR",{"type":57,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Jorge Gaete","Full Professor",[62,64],{"name":63,"class":6},"University of Talca",{"name":65,"class":66},"Fundación Crecer y Sanar","UNKNOWN","100597855","stratified-care-school-based-intervention-for-adolescent-suicidal-ideation-100597855",false,"NCT07063914","Stratified-Care School-Based Intervention for Adolescent Suicidal Ideation","Acceptability and Feasibility of a Stratified-Care School-Based Intervention for Adolescent Suicidal Ideation in Chile: A Study Protocol","Inclusion Criteria:\n\n* Inclusion Criteria for Educational Institutions\n\n  * Located in Santiago, Chile.\n  * Secondary education level (grades I-IV Medio).\n  * Coeducational schools.\n  * At least two classes per grade level in secondary education.\n  * A minimum of 30 students per class.\n  * Socioeconomic vulnerability level of ≥ 50%, as measured by the School Vulnerability Index (Índice de Vulnerabilidad Escolar - IVE-SINAE), which includes factors such as parental education and total household income.\n\nInclusion Criteria for Students\n\n* Enrolled in grades I, II, or III Medio.\n* Suicidal ideation within the past month, defined as a score ≥ 3 on the Columbia-Suicide Severity Rating Scale (C-SSRS).\n* For the Reframe-IT+ program: mild or moderate depressive symptoms, defined as a PHQ-9 score \\\u003C 20.\n* For the CARIBOU program: severe depressive symptoms, defined as a PHQ-9 score ≥ 20.\n\nExclusion Criteria:\n\n* Exclusion Criteria for Students\n\n  * Participation in a structured suicide prevention program (Reframe-IT+) during 2024.\n  * Severe psychotic symptoms, such as perceptual disturbances or delusional ideas, assessed during the eligibility interview.\n  * Suicide attempt(s) in the past three months, assessed during the eligibility interview.","ALL","14 Years","18 Years",{"count":78,"type":79},60,"ESTIMATED","INTERVENTIONAL",[82],"NA","Background. Suicidal ideation and depressive symptoms are highly prevalent among adolescents, with suicide representing a leading cause of death in this age group worldwide. School-based indicated prevention programs using cognitive behavioral therapy (CBT) have shown promise in addressing these mental health challenges. The Reframe-IT+ (Chile) and CARIBOU (Canada) programs are CBT-based, individually delivered interventions targeting adolescents at risk of suicide. This study aims to evaluate a culturally adapted stratified-care model using these two interventions, matched to depressive symptom severity.\n\nMethods. This is a quasi-experimental, single-arm study with pre-post assessments and follow-ups at 3, 6, 9, and 12 months. Six secondary schools with high socioeconomic vulnerability in Santiago, Chile, will participate. Students with suicidal ideation and mild\u002Fmoderate depressive symptoms (PHQ-9 \\\u003C 20) will be offered Reframe-IT+, while those with severe symptoms (PHQ-9 ≥ 20) will be offered CARIBOU. Primary outcomes include the acceptability of CARIBOU, feasibility of the stratified-care model, and implementation fidelity. Secondary outcomes include reductions in suicidal ideation, depression, anxiety, hopelessness, and improvements in functioning, quality of life, behavioral activation, emotional regulation, and problem-solving skills.\n\nDiscussion. This protocol addresses the need for scalable, culturally sensitive interventions for adolescent suicide prevention in school settings. By evaluating both the process and early outcomes of a stratified-care approach, this study will generate valuable evidence to inform future large-scale effectiveness trials and policy development in adolescent mental health.",[85],"Suicidal Ideation",[87,88,89,90,91],"suicide","adolescents","depression","schools","prevention","2025-07-29",{"date":94,"type":95},"2025-08-01","ACTUAL",{"date":97,"type":95},"2025-06-25",{"date":99,"type":79},"2025-12-31",{"name":5,"class":6},1]