[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643688":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":23,"centralContacts":34,"locations":23,"responsibleParty":40,"collaborators":44,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":23,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":77,"whyStopped":23,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":23},{"fullName":5,"class":6},"City University of New York, School of Public Health","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"streamlined IPT-G with streamlined Suubi+Adherence","EXPERIMENTAL","Streamlined IPT-G (6 weeks) one 90-min StrongMinds group counseling session per week \\& Suubi+Adherence (36 weeks)",[13,14],"Behavioral: Streamlined Suubi+Adherence","Behavioral: Streamlined Interpersonal Psychotherapy Groups (IPT-G)",{"label":16,"type":10,"description":17,"interventionNames":18},"streamlined IPT-G with SOC ART counseling","Streamlined IPT-G (6 weeks) as described above \\& Standard Of Care (SOC) ART counseling (8 weeks) individual 30-min counseling sessions once per week",[14],{"label":20,"type":21,"description":22,"interventionNames":23},"SOC mental health counseling with SOC ART counseling.","NO_INTERVENTION","Receive treatment per Uganda national guidelines Standard Of Care (SOC) Mental Health Counseling (6-weeks) delivered by HIV clinic staff in 60-min sessions once per week and SOC ART counseling (8-weeks).",null,[25,30],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":23},"BEHAVIORAL","Streamlined Suubi+Adherence","Participants in this intervention arm will receive:\n\n* Financial literacy training\n* Youth savings accounts The intervention aims to strengthen economic stability and support long-term treatment adherence and psychosocial well-being.",[9],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":23},"Streamlined Interpersonal Psychotherapy Groups (IPT-G)","* Participants in the IPT-G intervention arms will attend:\n* Six weekly group counseling sessions,\n* Conducted in groups of approximately 6-10 adolescents,\n* Facilitated by trained StrongMinds counselors.\n\nThe sessions will focus on:\n\n* Emotional wellbeing\n* Relationships\n* Coping with stress\n* Grief and loss\n* Social support\n* Problem-solving skills",[16,9],[35],{"name":36,"role":37,"phone":38,"phoneExt":23,"email":39},"Philip Kreniske, PhD","CONTACT","(646) 364-9600","philip.kreniske@sph.cuny.edu",{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Philip Kreniske","Assistant Professor",[45,48,50],{"name":46,"class":47},"National Institute of Mental Health (NIMH)","NIH",{"name":49,"class":6},"New York University",{"name":51,"class":52},"Washington University Bursky School of Public Health","UNKNOWN","100643688","streamlined-treatment-and-evidence-based-adolescent-counseling-and-medication-support-streams-100643688",false,"NCT07637058","Streamlined Treatment and Evidence-based Adolescent Counseling and Medication Support (STREAMS)","STREAMS","Inclusion Criteria:\n\n* Living with HIV with confirmation by medical report and aware of their status\n* Living within a family (defined broadly, not necessarily with biological parents); - - Between the ages of 15 to 19 years\n* Prescribed ART\n* Score a 10 or greater on the PHQ-9\n\nExclusion Criteria:\n\n* an inability to understand study procedures and participant rights as assessed during informed consent\u002Fassent process with the adolescent or caregiver.","ALL","15 Years","19 Years",{"count":64,"type":65},588,"ESTIMATED","INTERVENTIONAL",[68],"NA","Combination interventions to address mental health and adherence to HIV care in low- and middle-income countries (LMICs), are crucial to achieving the UNAIDS 95-95-95 targets as one in four adolescents living with HIV (ALWHIV) experience poor mental health and this contributes to suboptimal medication adherence and lack of viral suppression. Yet few evidence-based mental health and adherence interventions have been evaluated in sub-Saharan Africa (SSA), the region where the majority of the 1.7 million ALWHIV reside. STREAMS will determine if our streamlined combination intervention approach to mental health screening, provision of evidence-based interpersonal psychotherapy groups (IPT-G), and evidence-based family strengthening, and medication counseling is feasible and efficacious for ALWHIV in Uganda.",[71],"Depression in Adolescence",[73,74,75,76],"HIV","Uganda","mental health","depression","NOT_YET_RECRUITING","2026-06-04",{"date":80,"type":81},"2026-06-09","ACTUAL",{"date":83,"type":65},"2026-12",{"date":85,"type":65},"2030-08",{"name":5,"class":6}]