[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584723":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":11,"centralContacts":31,"locations":37,"responsibleParty":52,"collaborators":11,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":11,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":11,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":40,"whyStopped":11,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"General University Hospital, Prague","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Combined Strength-Endurance Circuit Training","EXPERIMENTAL",null,[13],"Other: Strength-Endurance Training",{"label":15,"type":16,"description":11,"interventionNames":17},"Endurance Circuit Training","ACTIVE_COMPARATOR",[18],"Other: Endurance Training",{"label":20,"type":21,"description":11,"interventionNames":11},"Control Group","NO_INTERVENTION",[23,27],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":11},"Strength-Endurance Training","The intervention for the experimental Strength-Endurance group includes warm-up, three laps of strength and endurance exercises and cool-down.\n\nThe training program lasts 3 months and includes two 1-hour training sessions per week, for a total of 24 sessions.",[9],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":11},"Endurance Training","The intervention for the control Endurance training group includes warm-up, three laps of endurance exercises and cool-down. The training program lasts 3 months and includes two 1-hour training sessions per week, for a total of 24 sessions.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":11,"email":36},"Jakub Vítek, MSc.","CONTACT","+420 224 965 513","jakub.vitek@vfn.cz",[38],{"facility":39,"status":40,"city":41,"state":41,"zip":42,"country":43,"countryCode":11,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Department of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague","RECRUITING","Prague","12000","Czechia",{"type":45,"coordinates":46},"Point",[47,48],14.42076,50.08804,{"lat":48,"lon":47},[51],{"name":33,"role":34,"phone":35,"phoneExt":11,"email":36},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Jakub Vítek","Physiotherapist","100584723","strength-endurance-circuit-training-in-parkinsons-disease-100584723",false,"NCT06893055","Strength-Endurance Circuit Training in Parkinson's Disease","Strength-Endurance Circuit Training in Parkinson's Disease: Effects on Disease Severity, Physical Performance, Blood Biomarkers and Quality of Life.","Inclusion Criteria:\n\n* age ≥18 years\n* diagnosis of idiopathic Parkinson´s disease\n* Hoehn-Yahr Scale ≤ 2,5\n* stable dopaminergic medication\n\nExclusion Criteria:\n\n* age ≥75 years\n* Hoehn-Yahr Scale ≥ 2,5\n* deep brain stimulation\n* presence of freezing\n* Camptocormia\n* inability to walk without support\n* inability to perform study procedures\n* limiting co-morbidities\n* attendance at training sessions below 70%","ALL","18 Years","75 Years",{"count":67,"type":68},90,"ESTIMATED","INTERVENTIONAL",[71],"NA","The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training.\n\n\\- Does combined strength-endurance circuit training provide added benefits to physical performance, disease severity, blood biomarkers, and quality of life in PD patients compared to standalone aerobic training?\n\nParticipants will:\n\n* undergo outcome measurements before and after the 12-week intervention and a 3-month follow-up measurement,\n* visit the clinic twice a week for 1-hour training sessions.\n* selected patients will be given a smartwatch with a pedometer that will count their average number of steps before, during and after the training period",[74],"Parkinson Disease, Idiopathic",[76,77,78,79,80,81,82],"Parkinson Disease","Strength training","Endurance training","Physiotherapy","Irisin","Quality of Life","Physical performance","2025-04-07",{"date":85,"type":86},"2025-04-09","ACTUAL",{"date":88,"type":86},"2025-03-03",{"date":90,"type":68},"2027-03",{"name":5,"class":6},1]