[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600980":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":58,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":25,"enrollmentInfo":70,"targetDuration":25,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Virginia Polytechnic Institute and State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Strenth Training","EXPERIMENTAL","Participants will undergo strength training 3 times per week for 14 weeks.",[13],"Behavioral: Strength Training",{"label":15,"type":6,"description":16,"interventionNames":17},"Waitlisted control","Participants will have no strength training intervention for 14 weeks. Participants will be offered the same 14-week strength training program after the initial 14 weeks.",[18],"Other: Wait first, then strength training",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Strength Training","Participants taking a GLP-1 will undergo a 14-week strength training regimen to determine changes in muscle mass. They will perform a series of resistance training exercises supervised by a personal trainer on 3 days per week.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Wait first, then strength training","Participants will be waitlisted and receive the 14-week strength training intervention at the end of the waitlist period. During the waitlist period, participants will get no intervention and then be offered the strength training intervention after the first 14 weeks.",[15],[31],{"name":32,"affiliation":5,"role":33},"Kevin Davy","PRINCIPAL_INVESTIGATOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","540-231-3487","kdavy@vt.edu",{"name":40,"role":36,"phone":41,"phoneExt":25,"email":42},"Elaina Marinik","540-231-0923","emarinik@vt.edu",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":25},"Virginia Tech","RECRUITING","Blacksburg","Virginia","24061","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-80.41394,37.22957,{"lat":56,"lon":55},{"type":33,"investigatorFullName":32,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Professor","100600980","strength-training-response-of-muscle-in-glp-1-users-100600980",false,"NCT07104539","Strength Training Response of Muscle in GLP-1 Users","STRONG-GLP","Inclusion Criteria:\n\n* Age, 50y+\n* Be taking GLP-1 medicine (Weygovy or Zepbound) for 1 month or less\n* Weight \\\u003C300 lb\n* Pass a health and exercise readiness screening\n\nExclusion Criteria:\n\n* Age \\\u003C50\n* Weight \\>300 lb\n* Osteoporosis\n* Active metabolic, neoplastic, or cardiovascular disease\n* Unable or unwilling to provide consent",true,"ALL","50 Years",{"count":71,"type":72},30,"ESTIMATED","INTERVENTIONAL",[75],"NA","GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function. Moreover, any loss of muscle mass or muscle function with GLP-1 treatment may impair balance and increase fall risk. This is a particular concern among older adults already susceptible to the common muscle strength and muscle function loss with age, yet there is little evidence among this population. This study will address a gap in knowledge regarding the effects of GLP-1 treatment on muscle mass, muscle function, and balance\u002Ffall risk among adults age 50 and older.",[78],"Muscle Mass",[80,81,82,83,84,85],"Weight loss","GLP-1 agonist","Obesity","Lean mass","Body composition","Strength training","2026-01-16",{"date":88,"type":89},"2026-01-21","ACTUAL",{"date":91,"type":89},"2025-10-08",{"date":93,"type":72},"2027-05",{"name":5,"class":6},1]