[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100404837":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":17,"centralContacts":21,"locations":31,"responsibleParty":69,"collaborators":71,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":16,"eligibilityCriteria":80,"healthyVolunteers":77,"sex":81,"minAge":82,"maxAge":16,"enrollmentInfo":83,"targetDuration":16,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":16,"overallStatus":34,"whyStopped":16,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Yale University","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Mental Stress","Patients will undergo a lab mental stress protocol, and a field protocol using ecological momentary assessment (EMA) to test the effects of psychological stress and negative emotion on PAP in HF patients.",[12],"Other: Mental Stress",[14],{"type":6,"name":9,"description":10,"armGroupLabels":15,"otherNames":16},[9],null,[18],{"name":19,"affiliation":5,"role":20},"Rachel Lampert, MD","PRINCIPAL_INVESTIGATOR",[22,26],{"name":19,"role":23,"phone":24,"phoneExt":16,"email":25},"CONTACT","(203) 737-4068","rachel.lampert@yale.edu",{"name":27,"role":23,"phone":28,"phoneExt":29,"email":30},"Matthew Burg","203-932-5711","3268","matthew.burg@yale.edu",[32,57],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"St. Francis Hospital","RECRUITING","Hartford","Connecticut","06105","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-72.68509,41.76371,{"lat":44,"lon":43},[47,51,55],{"name":48,"role":23,"phone":49,"phoneExt":16,"email":50},"Colleen Watters, APRN","860-714-6178","colleen.watters@trinityhealthofne.org",{"name":52,"role":23,"phone":53,"phoneExt":16,"email":54},"Megan Evjen, RN","860-714-4860","MEvjen@TrinityHealthOfNE.org",{"name":56,"role":20,"phone":16,"phoneExt":16,"email":16},"Saima Husain, MD",{"facility":5,"status":34,"city":58,"state":36,"zip":59,"country":38,"countryCode":39,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"New Haven","06511",{"type":41,"coordinates":61},[62,63],-72.92816,41.30815,{"lat":63,"lon":62},[66],{"name":67,"role":23,"phone":68,"phoneExt":16,"email":25},"Rachel Lampert","203-737-4068",{"type":70,"investigatorFullName":16,"investigatorTitle":16,"investigatorAffiliation":16,"oldNameTitle":16,"oldOrganization":16},"SPONSOR",[72],{"name":73,"class":74},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100404837","stress-and-congestive-heart-failure-100404837",false,"NCT04551560","Stress and Congestive Heart Failure","Inclusion Criteria:\n\n-Heart failure patients over 18 who have or will be receiving a Cardiomems implanted PAP monitor.\n\nExclusion Criteria:\n\n* Patients who are unable to perform EMA or laboratory assessments due to cognitive, visual, language, or other disabilities will be excluded.\n* Patients with Class IV heart failure will also be excluded, as they are already maximally decompensated, and a ceiling\u002Ffloor effect would preclude effects of stress.\n* Patients with conditions other than heart failure that affect PA pressures (e.g. dialysis).\n* Patients with physical conditions that interfere with study participation.\n* Patients non-compliant with their PAP monitoring.\n* Patients with chronic opioid use will be excluded.","ALL","18 Years",{"count":84,"type":85},112,"ESTIMATED","INTERVENTIONAL",[88],"NA","The purpose of this study is to investigate whether acute stress can precipitate congestive heart failure (CHF) exacerbation in patients with CHF.",[91],"Congestive Heart Failure","2026-01-26",{"date":94,"type":95},"2026-01-27","ACTUAL",{"date":97,"type":95},"2020-12-02",{"date":99,"type":85},"2026-04-30",{"name":5,"class":6},2]