[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541994":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":58,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":25,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":25,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"M.D. Anderson Cancer Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Troponin Surveillance","EXPERIMENTAL","Participants in Group 1, will have blood tests performed prior to each immune checkpoint inhibitor infusion for 12 weeks.",[13],"Diagnostic Test: Troponin surveillance",{"label":15,"type":10,"description":16,"interventionNames":17},"Standard of Care","Participants in Group 2, will have standard of care testing for any heart-related side effects of immune checkpoint inhibitors.",[18],"Other: Standard of care",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIAGNOSTIC_TEST","Troponin surveillance","Troponin will be monitored prior to each immune checkpoint inhibitor infusion for the first 12 weeks of therapy.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standard of care","Standard of care if symptoms arise then evaluation with cardiac biomarkers and\u002For further cardiac testing.",[15],[31],{"name":32,"affiliation":5,"role":33},"Nicolas Palaskas, MD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","(713) 606-3957","nlpalaskas@mdanderson.org",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"MD Anderson Cancer Center","RECRUITING","Houston","Texas","77030","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-95.36327,29.76328,{"lat":52,"lon":51},[55,57],{"name":32,"role":36,"phone":56,"phoneExt":25,"email":38},"713-606-3957",{"name":32,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":59,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100541994","strict---surveillance-with-troponin-during-immune-checkpoint-therapy-100541994",false,"NCT06337097","STRICT - Surveillance With TRoponin During Immune Checkpoint Therapy","Inclusion Criteria:\n\n* Male or female patient ≥18 years old\n* Plan for treatment with an immune checkpoint inhibitor as standard of care even if patient is also on an additional investigational cancer therapeutic\n* Willingness to provide informed consent\n\nExclusion Criteria:\n\n* Troponin T not available at screening or prior to randomization\n* Inability to comply with planned study procedures\n* Major adverse cardiovascular event included in the primary outcome within the 30 days prior to enrollment\n* Any medical condition that could interfere with, or for which the treatment might interfere with the conduct of the study or interpretation of the study results, or that would, in the opinion of the investigator, increase the risk of the participant by participating in the study\n* Any factors that, in the Investigator's opinion, are likely to interfere with study procedures, such as history of noncompliance with scheduled appointments.","ALL","18 Years",{"count":69,"type":70},980,"ESTIMATED","INTERVENTIONAL",[73],"NA","To learn if monitoring blood levels of heart injury (troponin levels) in cancer participants treated with immune checkpoint inhibitors will lead to decreased heart-related side effects.",[76],"Immune Checkpoint Therapy","2026-01-16",{"date":79,"type":80},"2026-01-20","ACTUAL",{"date":82,"type":80},"2024-02-02",{"date":84,"type":70},"2028-12-31",{"name":5,"class":6},1]