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Adult patients with shortness of breath and hyperinflation associated with severe emphysema and evidence of low collateral ventilation.\n2. Subjects must understand and voluntarily sign an informed consent form.\n\nExclusion Criteria:\n\n1. Subjects who are not appropriate for SVS therapy based upon the US FDA-approved IFU requirements.\n2. Subjects who were withdrawn from this study for any reason will not be allowed to re-enroll.\n3. Subjects who have incomplete screening or baseline data.","ALL","18 Years",{"count":283,"type":284},150,"ESTIMATED","3 Years","OBSERVATIONAL","This is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe emphysema in a post-market setting.",[289],"Emphysema",[289,291,292],"Chronic obstructive pulmonary disease (COPD)","Spiration valve system","2026-04-23",{"date":295,"type":296},"2026-04-24","ACTUAL",{"date":298,"type":296},"2021-10-09",{"date":300,"type":284},"2029-10",{"name":5,"class":6},14]