[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100537259":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":24,"centralContacts":29,"locations":34,"responsibleParty":64,"collaborators":66,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":23,"eligibilityCriteria":75,"healthyVolunteers":72,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":23,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":23,"overallStatus":54,"whyStopped":23,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Danderyd Hospital","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Systematic screening group","Individuals aged 75\u002F76 randomized to systematic screening are invited through a centralized screening facility to participate in prolonged ECG screening.",[12],"Behavioral: Screening invitation mode",{"label":14,"type":6,"description":15,"interventionNames":16},"Opportunistic screening group","Individuals aged 75\u002F76 randomized to opportunistic screening are invited to participate when they visit their primary care facility to prolonged ECG screening.",[12],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"BEHAVIORAL","Screening invitation mode","Cluster randomized study to compare mode of invitation",[14,9],null,[25],{"name":26,"affiliation":27,"role":28},"Emma Svennberg, MD PhD","Karolinska Institutet","PRINCIPAL_INVESTIGATOR",[30],{"name":26,"role":31,"phone":32,"phoneExt":23,"email":33},"CONTACT","+46739584822","emma.svennberg@regionstockholm.se",[35,52],{"facility":36,"status":37,"city":38,"state":23,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Karolinska Institutet, Dept Med H","NOT_YET_RECRUITING","Stockholm","141 86","Sweden","SE",{"type":43,"coordinates":44},"Point",[45,46],18.06871,59.32938,{"lat":46,"lon":45},[49,50],{"name":26,"role":31,"phone":32,"phoneExt":23,"email":33},{"name":51,"role":31,"phone":23,"phoneExt":23,"email":23},"MD PhD",{"facility":53,"status":54,"city":55,"state":23,"zip":23,"country":40,"countryCode":41,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"Region Värmland","RECRUITING","Värmland",{"type":43,"coordinates":57},[58,59],16.5,60.83333,{"lat":59,"lon":58},[62],{"name":63,"role":31,"phone":23,"phoneExt":23,"email":23},"Fredrik Carlstedt",{"type":65,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR",[67,68],{"name":27,"class":6},{"name":69,"class":6},"Landstinget i Värmland","100537259","strokestop-iii---optimized-method-for-atrial-fibrillation-screening-100537259",false,"NCT06275503","STROKESTOP III - Optimized Method for Atrial Fibrillation Screening","Inclusion Criteria:\n\n* Individuals aged 75\u002F76 in 2024 (born 1948, 1949)\n* Must reside in the region of Värmland\n* Must be listed at a primary care facility\n\nExclusion Criteria:\n\n* Treatment with oral anti coagulation treatment (OAC)\n* Contraindications for OAC treatment\n* Prior atrial fibrillation\n* Unable to provide consent","ALL","75 Years","76 Years",{"count":80,"type":81},2200,"ESTIMATED","INTERVENTIONAL",[84],"NA","Atrial fibrillation is the most common sustained cardiac arrhythmia affecting more than 3% of the adult population. The symptoms of atrial fibrillation can range from asymptomatic to debilitating. It can be permanent in its nature, but also paroxysmal with only short bursts of atrial fibrillation randomly occurring and can therefore remain unnoticed. Atrial fibrillation increases the risk of stroke five fold if left untreated.\n\nScreening for atrial fibrillation in elderly populations above age 65 years can result in detection of new atrial fibrillation cases ranging from 0,5% new AF with a single time-point ECG, up to 30% AF if an implantable loop recorder is inserted for 3 years.\n\nCurrently opportunistic screening using pulse palpation, or a single time-point ECG is recommended by the European Society of Cardiology guidelines. Systematic screening in individuals aged 75 or above, or at a high stroke risk should be considered.\n\nOverall, participation in systematic atrial fibrillation screening trials has been shown to be relatively low with almost 50% non-participants. Participants are generally healthier, with higher socioeconomic status, hence the ones who would potentially benefit the most remain absent.\n\nOpportunistic screening has shown promising results with higher participation rates and the possibility of better outreach. There is a lack of data from randomized trials on the difference in participation rates in systematic and opportunistic screening approaches when screening with prolonged ECG monitoring.",[87,88],"Atrial Fibrillation","Atrial Fibrillation New Onset","2024-05-03",{"date":91,"type":92},"2024-05-06","ACTUAL",{"date":94,"type":92},"2024-05-02",{"date":96,"type":81},"2026-06-30",{"name":5,"class":6},2]