[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632343":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":17,"responsibleParty":37,"collaborators":7,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":42,"sex":48,"minAge":49,"maxAge":7,"enrollmentInfo":50,"targetDuration":7,"studyType":53,"phases":7,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":59,"whyStopped":7,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},{"fullName":5,"class":6},"Azienda Ospedaliero, Universitaria Pisana","OTHER",null,[9,14],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Maurizio Mazzantini, MD","CONTACT","+39","mau.mazzantini@gmail.com",{"name":15,"role":11,"phone":12,"phoneExt":7,"email":16},"Giammarco De Mattia, MD","demattia.giammaco@hsr.it",[18],{"facility":19,"status":7,"city":20,"state":21,"zip":22,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"AOUP Stabilimento di Santa Chiara - UO Endocrinologia","Pisa","PI","56126","Italy","IT",{"type":26,"coordinates":27},"Point",[28,29],10.4036,43.70853,{"lat":29,"lon":28},[32,33,35],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},{"name":15,"role":11,"phone":12,"phoneExt":7,"email":34},"demattia.giammarco@hsr.it",{"name":10,"role":36,"phone":7,"phoneExt":7,"email":7},"PRINCIPAL_INVESTIGATOR",{"type":36,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Maurizio Mazzantini","MD","100632343","study-in-patients-with-osteoporosis-and-fragility-fractures-to-estimate-the-extent-and-impact-of-delayed-administration-of-anti-fracture-therapy-100632343",false,"NCT07512453","Study in Patients With Osteoporosis and Fragility Fractures to Estimate the Extent and Impact of Delayed Administration of Anti-fracture Therapy","Retrospective Multicenter Study in Patients With Osteoporosis and Fragility Fractures to Estimate the Extent and Impact of Delayed Administration of Anti-fracture Therapy","OPGAP01","Inclusion Criteria:\n\n* adult patients of both sexes;\n* patients with osteoporosis and\u002For previous fragility fractures (fragility fractures are defined as those that occur spontaneously, i.e., not resulting from trauma, even of low intensity, or those caused by a fall from standing height.\n* willingness to sign the consent form\n\nExclusion Criteria:\n\n* patients under the age of 18\n* no previous fragility fractures - failure to sign the consent form Exit criteria","ALL","18 Years",{"count":51,"type":52},8000,"ESTIMATED","OBSERVATIONAL","Osteoporosis (OP) and fragility fractures are a significant problem that leads to morbidity, mortality, and high costs for the National Health System. The treatment of fragility fractures includes numerous anti-resorptive and anabolic drugs, and its goal is the secondary prevention of new fractures. It is well known that the risk of a new fracture following a fracture event is highest in the months immediately following the first fracture. However, recent data clearly show a dramatic global delay in the administration of anti-osteoporotic therapy following a fragility fracture. It has been estimated that in Italy, 71% of patients with fragility fractures eligible for anti-fracture treatment did not receive timely treatment (a problem defined as a \"treatment gap\"), and that in 2034, the incidence of new fragility fractures will increase compared to 2019 \\[1\\]. However, there is a lack of real-life Italian data on the extent of the treatment gap in osteoporotic patients with fragility fractures and its impact in terms of the incidence of subsequent fragility fractures: this study therefore aims to fill this gap by collecting data from a large population of patients attending several centers throughout the country.",[56],"Osteoporosis",[58],"fractures and fragility","NOT_YET_RECRUITING","2026-04-01",{"date":62,"type":63},"2026-04-06","ACTUAL",{"date":60,"type":52},{"date":66,"type":52},"2029-03-31",{"name":5,"class":6},1]