[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100486394":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":34,"centralContacts":39,"locations":45,"responsibleParty":62,"collaborators":66,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":24,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":24,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":96,"overallStatus":100,"whyStopped":24,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Nanjing University of Traditional Chinese Medicine","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment group A","ACTIVE_COMPARATOR","Treatment group A was given endocrine and acupuncture treatment for 8 weeks (24 times in total, 3 times a week); followed up for 16 weeks, no acupuncture treatment.",[13],"Other: Acupuncture treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Treatment group B","SHAM_COMPARATOR","Treatment group B was given endocrine and sham acupuncture treatment for 8 weeks, followed up for 16 weeks, no acupuncture during the period, and after 16 weeks, received standardized acupuncture for 8 weeks (24 times in total, 3 times a week).",[19],"Other: Sham acupuncture treatment",{"label":21,"type":22,"description":23,"interventionNames":24},"control","NO_INTERVENTION","The control group was given conventional adjuvant endocrine therapy, premenopausal patients received tamoxifen therapy, and postmenopausal patients received aromatase inhibitor or tamoxifen therapy.",null,[26,30],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":24},"Acupuncture treatment","Acupoint selection: 4 general points + syndrome differentiation acupoints (select or replace 2-4 acupoints according to symptom 1, select 1-2 acupoints according to symptom 2 and symptom 3), and adjust acupoints according to symptoms every week.\n\nFrequency: 3 times a week (once every other day) for a total of 8 weeks of continuous treatment.\n\nOperation: Use a one-time sterile acupuncture needle (0.30×40mm, Huatuo brand), insert the needle 0.5 inch along the anatomical position, level up and relieve the qi, and keep the needle for 20 minutes.",[9],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":24},"Sham acupuncture treatment","Acupoint selection: According to the selected acupoints of the electroacupuncture group, 5-7 positions were selected at the non-meridian and non-acupoint points(points with less nerve distribution, sparseness, and rich muscles).\n\nFrequency: 3 times a week (once every other day) for a total of 8 weeks of continuous treatment.\n\nOperation: ① Shallow needling scheme: use a disposable sterile acupuncture needle, insert the needle 0.2 inch, without twisting, and keep the needle for 20 minutes. ②Non-invasive acupuncture plan: choose a special comfort needle with no needle tip at the top of the needle, paste a disposable sterile foam pad on the non-acupoint, and use a disposable sterile flat head The acupuncture needles were pierced into the foam pad, lightly touching but not piercing the skin, and not breathing; the needles were kept for 20 minutes.",[15],[35],{"name":36,"affiliation":37,"role":38},"Lijun Bai","Xi'an Jiaotong University","STUDY_DIRECTOR",[40],{"name":41,"role":42,"phone":43,"phoneExt":24,"email":44},"Lijun Bai, phd","CONTACT","0086-15129034948","bailijun@xjtu.edu.cn",[46],{"facility":47,"status":24,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Jiangsu Province Hospital of Traditional Chinese Medcine","Nanjing","Jiangsu","210029","China","CN",{"type":54,"coordinates":55},"Point",[56,57],118.77778,32.06167,{"lat":57,"lon":56},[60],{"name":61,"role":42,"phone":43,"phoneExt":24,"email":44},"Lijun Bai, PHD",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Qianyan Liu","Principal Investgator",[67,68,71,73],{"name":37,"class":6},{"name":69,"class":70},"Hanzhong Hospital of Traditional Chinese Medicine","UNKNOWN",{"name":72,"class":6},"Xiang'an Hospital of Xiamen University",{"name":74,"class":6},"Dongzhimen Hospital, Beijing","100486394","study-of-acupuncture-in-the-treatment-of-hot-flashes-in-patients-with-hormone-receptor-positive-breast-cancer-100486394",false,"NCT05613504","Study of Acupuncture in the Treatment of Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.","A Randomized Controlled Trial Study of Acupuncture in the Treatment of Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.","Inclusion Criteria:\n\n* Aged 30-75 years old;\n* Adjuvant hormone therapy (eg, tamoxifen and\u002For aromatase inhibitors) with or without ovarian function suppression has been administered for at least 4 weeks and is currently on treatment;\n* Patients with persistent hot flashes for at least 4 weeks and with a frequency of more than 14 hot flashes per week (2 times per day) in the week before inclusion in the study, the weekly average hot flash composite score is 3-4;\n* Patients after surgery and chemotherapy (if any);\n* Eastern Cooperative Oncology Group score of 0-1 points.\n* Sign the informed consent and participate in the clinical observation voluntarily.\n\nExclusion Criteria:\n\n* Tumor metastases, undergoing chemoradiotherapy or planning surgery;\n* Pharmacological intervention for hot flashes with hot flash treatment drugs such as selective serotonin reuptake inhibitors (SSRIs) and\u002For anticonvulsants for at least 4 weeks prior to study initiation;\n* Patients receiving phytoestrogens, tibolone or analogs, verapril, or specific homeopathic medicines;\n* Started or changed adjuvant hormone therapy within the past week, or who planned to start or change adjuvant hormone therapy in the past 14 weeks, pregnant or breastfeeding patients;\n* Bleeding or coagulation disorders with obvious uncontrolled infection\n* Psychiatric illness or family history; neurological disorder or family history; seizure possibility or history of seizures.","FEMALE","30 Years","75 Years",{"count":86,"type":87},90,"ESTIMATED","INTERVENTIONAL",[90],"NA","This study intends to further evaluate the efficacy of acupuncture by comparing the intervention effects of different acupuncture treatment regimens on hot flashes in breast cancer ; and to explore the central effect regulation mechanism of acupuncture intervention on hot flashes based on integrated PET\u002FMRI technology.",[93,94,95],"Hot Flashes","Breast Cancer","Acupuncture",[97,95,98,99],"breast cancer","Integrated PET\u002FMRI technology","Hot flashes","NOT_YET_RECRUITING","2022-11-11",{"date":103,"type":104},"2022-11-16","ACTUAL",{"date":106,"type":87},"2022-12-01",{"date":108,"type":87},"2027-12-01",{"name":5,"class":6},1]