[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100507672":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":10,"responsibleParty":30,"collaborators":10,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":38,"eligibilityCriteria":39,"healthyVolunteers":34,"sex":40,"minAge":41,"maxAge":10,"enrollmentInfo":42,"targetDuration":10,"studyType":45,"phases":10,"briefSummary":46,"conditions":47,"keywords":52,"overallStatus":57,"whyStopped":10,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":10},{"fullName":5,"class":6},"University Hospital, Strasbourg, France","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with microvascular inflammation",null,"Patients presenting with microvascular inflammation on kidney allograft biopsy",[13],"Biological: Blood draw, Urine draw",{"label":15,"type":10,"description":16,"interventionNames":17},"Patient without microvascular inflammation","Patients presenting without microvascular inflammation on kidney allograft biopsy",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"BIOLOGICAL","Blood draw, Urine draw","Collection of an additional volume of blood at each follow-up time in addition to the standard blood test performed during the patient's follow-up Collection of an additional volume of urine at each follow-up time",[15,9],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Sophie CAILLARD-OHLMANN, PU-PH","CONTACT","03 69 55 05 11","sophie.caillard@chru-strasbourg.fr",{"type":31,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100507672","study-of-alloimmune-response-in-humoral-rejection-after-kidney-transplantation-100507672",false,"NCT05890430","Study of Alloimmune Response in Humoral Rejection After Kidney Transplantation","Study of Alloimmune Response in Humoral Rejection After Kidney Transplantation \"REjet Cellules Immunitaires Transplantation rEnale\" (RECITE)","RECITE","Inclusion Criteria:\n\n* Kidney transplant recipient, male or female, 18 years of age or older\n* Patient undergoing a kidney allograft biopsy, according to the usual protocol of the service\n* Subject affiliated with a social health insurance scheme.\n* Subject capable of understanding the objectives and risks associated with the research and expressing non-opposition\n\nExclusion Criteria:\n\n* Inability to provide the subject with clear and proper information (difficulties in understanding the subject, ...)\n* Refusal of the patient to participate in the study\n* Subject under guardianship or curatorship\n* Subjects under legal protection","ALL","18 Years",{"count":43,"type":44},570,"ESTIMATED","OBSERVATIONAL","We will study a prospective cohort including all kidney transplant recipients undergoing kidney graft biopsy in one kidney transplantation center, for a duration of 5 years.\n\nOur primary outcome is to compare the number of circulating NK cells between patients and without humoral rejection.\n\nOur secondary outcomes are to describe the cellular, genetic, humoral, and histological characteristics of humoral rejection and their evolution.",[48,49,50,51],"Kidney Transplantation","Kidney Allograft Biopsy","Humoral Rejection","Microvascular Inflammation",[48,53,54,55,56],"Humoral rejection","Kidney allograft biopsy","Alloimmunization","Genetic incompatibilities","NOT_YET_RECRUITING","2023-06-06",{"date":60,"type":61},"2023-06-08","ACTUAL",{"date":63,"type":44},"2023-06",{"date":65,"type":44},"2033-07",{"name":5,"class":6}]